Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yeri Lee"'
Autor:
Yeri Lee, Donggeon Kim, Philip E. D. Chung, Minkyeong Lee, Nahmju Kim, Jihoon Chang, Byoung Chul Lee
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 8, Pp 2227-2242 (2024)
Abstract Introduction KNP-301 is a bi-specific fragment crystallizable region (Fc) fusion protein, which inhibits both C3b and vascular endothelial growth factor (VEGF) simultaneously for patients with late-stage age-related macular degeneration (AMD
Externí odkaz:
https://doaj.org/article/96ffc668d5bb4881a96f90552c64a4d6
Autor:
Hye-Min Jeon, Yong Jae Shin, Jaehyun Lee, Nakho Chang, Dong-Hun Woo, Won Jun Lee, Dayna Nguyen, Wonyoung Kang, Hee Jin Cho, Heekyoung Yang, Jin-Ku Lee, Jason K. Sa, Yeri Lee, Dong Geon Kim, Benjamin W. Purow, Yeup Yoon, Do-Hyun Nam, Jeongwu Lee
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
Glioblastoma (GBM) is the most lethal brain cancer with a dismal prognosis. Stem-like GBM cells (GSCs) are a major driver of GBM propagation and recurrence; thus, understanding the molecular mechanisms that promote GSCs may lead to effective therapeu
Externí odkaz:
https://doaj.org/article/8ea1cbbe2cb049948a953837f0efb51e
Autor:
Seung Won Choi, Yeri Lee, Kayoung Shin, Harim Koo, Donggeon Kim, Jason K. Sa, Hee Jin Cho, Hye-mi Shin, Se Jeong Lee, Hyunho Kim, Seok Chung, Jihye Shin, Cheolju Lee, Do-Hyun Nam
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Abstract PTEN is one of the most frequently altered tumor suppressor genes in malignant tumors. The dominant-negative effect of PTEN alteration suggests that the aberrant function of PTEN mutation might be more disastrous than deletion, the most freq
Externí odkaz:
https://doaj.org/article/5efec489251247878b469f04eabfdbe7
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy
Autor:
Soniya Bastola, Marat S. Pavlyukov, Daisuke Yamashita, Sadashib Ghosh, Heejin Cho, Noritaka Kagaya, Zhuo Zhang, Mutsuko Minata, Yeri Lee, Hirokazu Sadahiro, Shinobu Yamaguchi, Svetlana Komarova, Eddy Yang, James Markert, Louis B. Nabors, Krishna Bhat, James Lee, Qin Chen, David K. Crossman, Kazuo Shin-Ya, Do-Hyun Nam, Ichiro Nakano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Intratumoural spatial heterogeneity is crucial to enhance therapeutic resistance in glioblastoma. Here, the authors show a paracrine signaling mechanism where glioblastoma-initiating cells located in the tumour edge elevate their malignancy by intera
Externí odkaz:
https://doaj.org/article/07b5f2bb5b4a4838a58f12fd8d7ba3c5
Autor:
Jason K. Sa, Nakho Chang, Hye Won Lee, Hee Jin Cho, Michele Ceccarelli, Luigi Cerulo, Jinlong Yin, Sung Soo Kim, Francesca P. Caruso, Mijeong Lee, Donggeon Kim, Young Taek Oh, Yeri Lee, Nam-Gu Her, Byeongkwi Min, Hye-Jin Kim, Da Eun Jeong, Hye-Mi Kim, Hyunho Kim, Seok Chung, Hyun Goo Woo, Jeongwu Lee, Doo-Sik Kong, Ho Jun Seol, Jung-Il Lee, Jinho Kim, Woong-Yang Park, Qianghu Wang, Erik P. Sulman, Amy B. Heimberger, Michael Lim, Jong Bae Park, Antonio Iavarone, Roel G. W. Verhaak, Do-Hyun Nam
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional heterogeneity. GBM can be subcategorized into four distinct subtypes; tumors that shift towards the mesenchymal phenotype upon recurrence are gen
Externí odkaz:
https://doaj.org/article/e8da640943fc48ff98c50176324f09fa
Autor:
Jason K. Sa, Jung Yong Hong, In-Kyoung Lee, Ju-sun Kim, Moon-Hee Sim, Ha Jung Kim, Ji Yeong An, Tae Sung Sohn, Joon Ho Lee, Jae Moon Bae, Sung Kim, Kyoung-Mee Kim, Seung Tae Kim, Se Hoon Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Nam-Gu Her, Yeri Lee, Hee Jin Cho, Yong Jae Shin, Misuk Kim, Harim Koo, Mirinae Kim, Yun Jee Seo, Ja Yeon Kim, Min-Gew Choi, Do-Hyun Nam, Jeeyun Lee
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Background Gastric cancer is among the most lethal human malignancies. Previous studies have identified molecular aberrations that constitute dynamic biological networks and genomic complexities of gastric tumors. However, the clinical trans
Externí odkaz:
https://doaj.org/article/e3c6324d78024d96b48dab76583ff8c6
Publikováno v:
BMJ Open, Vol 11, Iss 8 (2021)
Objectives To detect the signals for drospirenone-containing oral contraceptives (DCOCs) and describe the reporting pattern of adverse events (AEs) caused by DCOCs compared with levonorgestrel/desogestrel/gestodene-containing (second/third generation
Externí odkaz:
https://doaj.org/article/0cf3a901b9ee45daa1af2fa68c54a01a
Autor:
Jason K. Sa, Jae Ryoung Hwang, Young-Jae Cho, Ji-Yoon Ryu, Jung-Joo Choi, Soo Young Jeong, Jihye Kim, Myeong Seon Kim, E. Sun Paik, Yoo-Young Lee, Chel Hun Choi, Tae-Joong Kim, Byoung-Gie Kim, Duk-Soo Bae, Yeri Lee, Nam-Gu Her, Yong Jae Shin, Hee Jin Cho, Ja Yeon Kim, Yun Jee Seo, Harim Koo, Jeong-Woo Oh, Taebum Lee, Hyun-Soo Kim, Sang Yong Song, Joon Seol Bae, Woong-Yang Park, Hee Dong Han, Hyung Jun Ahn, Anil K. Sood, Raul Rabadan, Jin-Ku Lee, Do-Hyun Nam, Jeong-Won Lee
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Gynecologic malignancy is one of the leading causes of mortality in female adults worldwide. Comprehensive genomic analysis has revealed a list of molecular aberrations that are essential to tumorigenesis, progression, and metasta
Externí odkaz:
https://doaj.org/article/0c0c58115d8540249a37b73352d76232
Autor:
Mutsuko Minata, Alessandra Audia, Junfeng Shi, Songjian Lu, Joshua Bernstock, Marat S. Pavlyukov, Arvid Das, Sung-Hak Kim, Yong Jae Shin, Yeri Lee, Harim Koo, Kirti Snigdha, Indrayani Waghmare, Xing Guo, Ahmed Mohyeldin, Daniel Gallego-Perez, Jia Wang, Dongquan Chen, Peng Cheng, Farah Mukheef, Minerva Contreras, Joel F. Reyes, Brian Vaillant, Erik P. Sulman, Shi-Yuan Cheng, James M. Markert, Bakhos A. Tannous, Xinghua Lu, Madhuri Kango-Singh, L. James Lee, Do-Hyun Nam, Ichiro Nakano, Krishna P. Bhat
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1893-1905.e7 (2019)
Summary: Unresectable glioblastoma (GBM) cells in the invading tumor edge can act as seeds for recurrence. The molecular and phenotypic properties of these cells remain elusive. Here, we report that the invading edge and tumor core have two distinct
Externí odkaz:
https://doaj.org/article/10c885e108604068b2ac13b7bda6733f
Autor:
Yeri Lee, Kang Ho Kim, Dong Geon Kim, Hee Jin Cho, Yeonghwan Kim, Jinguen Rheey, Kayoung Shin, Yun Jee Seo, Yeon-Sook Choi, Jung-Il Lee, Jeongwu Lee, Kyeung Min Joo, Do-Hyun Nam
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0137703 (2015)
Glioblastoma (GBM) is the most aggressive and most lethal brain tumor. As current standard therapy consisting of surgery and chemo-irradiation provides limited benefit for GBM patients, novel therapeutic options are urgently required. Forkhead box M1
Externí odkaz:
https://doaj.org/article/bf32ec9cfbbb4ceab8cf481937a7900f