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Akademický článek

Variations in DNA methylation and the role of regulatory factors in rice (Oryza sativa) response to lunar orbit stressors

Autor: Xiaohui Du, Yan Zhang, Meng Zhang, Yeqing Sun

Publikováno v: Frontiers in Plant Science, Vol 15 (2024)

Deep space flight imposes higher levels of damage on biological organisms; however, its specific effects on rice remain unclear. To investigate the variations in DNA methylation under deep space flight conditions, this study examined rice seeds carri

Externí odkaz: https://doaj.org/article/3790df759bcb42c083a91035b53506e3

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Akademický článek

Using single-sample networks and genetic algorithms to identify radiation-responsive genes in rice affected by heavy ions of the galactic cosmic radiation with different LET values

Autor: Yan Zhang, Wei Wang, Meng Zhang, Binquan Zhang, Shuai Gao, Meng Hao, Dazhuang Zhou, Lei Zhao, Guenther Reitz, Yeqing Sun

Publikováno v: Frontiers in Plant Science, Vol 15 (2024)

IntroductionHeavy ions of the galactic cosmic radiation dominate the radiation risks and biological effects for plants under spaceflight conditions. However, the biological effects and sensitive genes caused by heavy ions with different linear energy

Externí odkaz: https://doaj.org/article/115d7f77d3b44ccd995948b0dd772db5

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Akademický článek

Using single-sample networks to identify the contrasting patterns of gene interactions and reveal the radiation dose-dependent effects in multiple tissues of spaceflight mice

Autor: Yan Zhang, Lei Zhao, Yeqing Sun

Publikováno v: npj Microgravity, Vol 10, Iss 1, Pp 1-14 (2024)

Abstract Transcriptome profiles are sensitive to space stressors and serve as valuable indicators of the biological effects during spaceflight. Herein, we transformed the expression profiles into gene interaction patterns by single-sample networks (S

Externí odkaz: https://doaj.org/article/d493cab8f9ac4650ae5f9e59f9792d92

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Akademický článek

SARS-CoV-2 Neutralization Assays Used in Clinical Trials: A Narrative Review

Autor: Yeqing Sun, Weijin Huang, Hongyu Xiang, Jianhui Nie

Publikováno v: Vaccines, Vol 12, Iss 5, p 554 (2024)

Since the emergence of COVID-19, extensive research efforts have been undertaken to accelerate the development of multiple types of vaccines to combat the pandemic. These include inactivated, recombinant subunit, viral vector, and nucleic acid vaccin

Externí odkaz: https://doaj.org/article/09b15c3852a0449aaeb32aeb36b91560

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Akademický článek

A functional gene module identification algorithm in gene expression data based on genetic algorithm and gene ontology

Autor: Yan Zhang, Weiyu Shi, Yeqing Sun

Publikováno v: BMC Genomics, Vol 24, Iss 1, Pp 1-18 (2023)

Abstract Since genes do not function individually, the gene module is considered an important tool for interpreting gene expression profiles. In order to consider both functional similarity and expression similarity in module identification, GMIGAGO,

Externí odkaz: https://doaj.org/article/3115a1648e2348c880f6b79d0042f10b

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Akademický článek

Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination

Autor: Meiyu Wang, Li Zhang, Qianqian Li, Bo Wang, Ziteng Liang, Yeqing Sun, Jianhui Nie, Jiajing Wu, Xiaodong Su, Xiaowang Qu, Yuhua Li, Youchun Wang, Weijin Huang

Publikováno v: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 18-29 (2022)

Severe acute respiratory syndrome coronavirus 2 variants have continued to emerge in diverse geographic locations with a temporal distribution. The Lambda variant containing multiple mutations in the spike protein, has thus far appeared mainly in Sou

Externí odkaz: https://doaj.org/article/dca44f6e3d4a4713ba1d3f31852b67fe

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Akademický článek

Analysis of the evolution, infectivity and antigenicity of circulating rabies virus strains

Autor: Meina Cai, Haizhou Liu, Fei Jiang, Yeqing Sun, Wenbo Wang, Yimeng An, Mengyi Zhang, Xueli Li, Di Liu, Yuhua Li, Yongxin Yu, Weijin Huang, Youchun Wang

Publikováno v: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1474-1487 (2022)

Rabies virus has existed for thousands of years and is circulating in many species. In the present study, a total of 2896 rabies viruses isolated worldwide were phylogenetically classified into ten clusters based on the G gene sequence, and these clu

Externí odkaz: https://doaj.org/article/a9fc29d955df483b964041974ca5b227

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Akademický článek

Modeling of ionizing radiation-induced chromosome aberration and tumor prevalence based on two classes of DNA double-strand breaks clustering in chromatin domains

Autor: Lei Zhao, Aiping Tang, Fei Long, Dong Mi, Yeqing Sun

Publikováno v: Ecotoxicology and Environmental Safety, Vol 259, Iss , Pp 115038- (2023)

There has been some controversy over the use of radiobiological models when modeling the dose-response curves of ionizing radiation (IR)-induced chromosome aberration and tumor prevalence, as those curves usually show obvious non-targeted effects (NT

Externí odkaz: https://doaj.org/article/014d609a2e904d998b4eae7dbd5fd97a

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