Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yeqing Angela, Yang"'
Autor:
Alessandra Castiglioni, Yagai Yang, Katherine Williams, Alvin Gogineni, Ryan S. Lane, Amber W. Wang, Justin A. Shyer, Zhe Zhang, Stephanie Mittman, Alan Gutierrez, Jillian L. Astarita, Minh Thai, Jeffrey Hung, Yeqing Angela Yang, Tony Pourmohamad, Patricia Himmels, Marco De Simone, Justin Elstrott, Aude-Hélène Capietto, Rafael Cubas, Zora Modrusan, Wendy Sandoval, James Ziai, Stephen E. Gould, Wenxian Fu, Yulei Wang, James T. Koerber, Shomyseh Sanjabi, Ira Mellman, Shannon J. Turley, Sören Müller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract TGFβ signaling is associated with non-response to immune checkpoint blockade in patients with advanced cancers, particularly in the immune-excluded phenotype. While previous work demonstrates that converting tumors from excluded to inflamed
Externí odkaz:
https://doaj.org/article/fa5b40b8c1aa4ad3abed292446b9c3af
Autor:
Akshay T. Krishnamurty, Justin A. Shyer, Minh Thai, Vineela Gandham, Matthew B. Buechler, Yeqing Angela Yang, Rachana N. Pradhan, Amber W. Wang, Patricia L. Sanchez, Yan Qu, Beatrice Breart, Cécile Chalouni, Debra Dunlap, James Ziai, Justin Elstrott, Neelie Zacharias, Weiguang Mao, Rebecca K. Rowntree, Jack Sadowsky, Gail D. Lewis, Thomas H. Pillow, Barzin Y. Nabet, Romain Banchereau, Lucinda Tam, Roger Caothien, Natasha Bacarro, Merone Roose-Girma, Zora Modrusan, Sanjeev Mariathasan, Sören Müller, Shannon J. Turley
Publikováno v:
Nature. 611:148-154
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15)1–3. However, the molecular sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1180240064ddca96a7dbfb51299c508a
https://doi.org/10.1038/s41586-022-05272-1
https://doi.org/10.1038/s41586-022-05272-1
Autor:
Ali Zhang, Jonathan C. Zhao, Jung Kim, Ka-wing Fong, Yeqing Angela Yang, Debabrata Chakravarti, Yin-Yuan Mo, Jindan Yu
Publikováno v:
Cell Reports, Vol 13, Iss 1, Pp 209-221 (2015)
Understanding the mechanisms of androgen receptor (AR) activation in the milieu of low androgen is critical to effective treatment of castration-resistant prostate cancer (CRPC). Here, we report HOTAIR as an androgen-repressed lncRNA, and, as such, i
Externí odkaz:
https://doaj.org/article/665f5d4981a44ca8949e0fc92853824b
Autor:
Sandra Rost, Zora Modrusan, Ciara Martin, Yeqing Angela Yang, Sangeeta Jayakar, Veronica Ibarra-Lopez
Publikováno v:
Journal of Visualized Experiments.
Multiplexing enables the assessment of several markers on the same tissue while providing spatial context. Spatial Omics technologies allow both protein and RNA multiplexing by leveraging photo-cleavable oligo-tagged antibodies and probes, respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f818f7447d66e2e59b516cefa77692
https://doi.org/10.3791/62651-v
https://doi.org/10.3791/62651-v
Autor:
Yeqing Angela Yang, Christian Cox, Matthew B. Buechler, Zora Modrusan, Merone Roose-Girma, Rachana N. Pradhan, Roger Caothien, Richard Bourgon, Sören Müller, Amber W. Wang, Akshay T. Krishnamurty, Shannon J. Turley, Aslihan Karabacak Calviello, Joseph R. Arron, Lucinda Tam
Publikováno v:
Nature. 593:575-579
Fibroblasts are non-haematopoietic structural cells that define the architecture of organs, support the homeostasis of tissue-resident cells and have key roles in fibrosis, cancer, autoimmunity and wound healing1. Recent studies have described fibrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cd94afe9f708264d32b72292b58008
https://doi.org/10.1038/s41586-021-03549-5
https://doi.org/10.1038/s41586-021-03549-5
Autor:
Alessandra Castiglioni, Markus Brown, Jillian L. Astarita, Mark Z. Chen, Lucinda Tam, Richard Bourgon, Claudia X. Dominguez, Shilpa Keerthivasan, Cecile Chalouni, Wendy Sandoval, Viviana Cremasco, Xiumin Wu, Yeqing Angela Yang, Andrey S. Shaw, Frederic J. de Sauvage, Ira Mellman, Elaine E. Storm, Catherine B Carbone, Merone Roose-Girma, Zora Modrusan, Amber W. Wang, Akshay T. Krishnamurty, Yasin Senbabaoglu, Wyne P. Lee, Jonas Doerr, Maximilian Nitschké, Shannon J. Turley, Varun N. Kapoor, Ryan Lane, Sören Müller, Christine Moussion
Publikováno v:
Nature Immunology. 22:571-585
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2383e3a737dd8c2478d0ddc2038bf224
https://doi.org/10.1038/s41590-021-00920-6
https://doi.org/10.1038/s41590-021-00920-6
Autor:
Akshay T, Krishnamurty, Justin A, Shyer, Minh, Thai, Vineela, Gandham, Matthew B, Buechler, Yeqing Angela, Yang, Rachana N, Pradhan, Amber W, Wang, Patricia L, Sanchez, Yan, Qu, Beatrice, Breart, Cécile, Chalouni, Debra, Dunlap, James, Ziai, Justin, Elstrott, Neelie, Zacharias, Weiguang, Mao, Rebecca K, Rowntree, Jack, Sadowsky, Gail D, Lewis, Thomas H, Pillow, Barzin Y, Nabet, Romain, Banchereau, Lucinda, Tam, Roger, Caothien, Natasha, Bacarro, Merone, Roose-Girma, Zora, Modrusan, Sanjeev, Mariathasan, Sören, Müller, Shannon J, Turley
Publikováno v:
Nature. 611(7934)
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59eeda4a38c0af3f0f6cad81ea9ce623
https://pubmed.ncbi.nlm.nih.gov/36171287
https://pubmed.ncbi.nlm.nih.gov/36171287
Autor:
Thi Thu Thao Nguyen, Zora Modrusan, Benjamin Haley, Xin Ye, Marie Evangelista, Yeqing Angela Yang, Matthew T. Chang, Sayumi Yamazoe, Shiva Malek, Lewis J. Gazzard, Ingrid E. Wertz, Robert Piskol, Frances Shanahan, Steven T. Staben, Scott A. Foster
Publikováno v:
Nature biotechnology. 40(1)
Genetic and non-genetic heterogeneity within cancer cell populations represent major challenges to anticancer therapies. We currently lack robust methods to determine how preexisting and adaptive features affect cellular responses to therapies. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49837d933856fb312b2bbc9339db6d1f
https://pubmed.ncbi.nlm.nih.gov/34531539
https://pubmed.ncbi.nlm.nih.gov/34531539
Autor:
Zora Modrusan, Yeqing Angela Yang, Yoko Oei, Lucinda Tam, Bushra Husain, Merone Roose-Girma, Yasin Senbabaoglu, James T. Koerber, Racquel Corpuz, Trent Hinkle, Shravan Madireddi, Samantha Carlisle, Shannon J. Turley, Nadia Martinez-Martin, Anne Wong, Victoria Pham, Zhengmao Ye, Shilpa Keerthivasan, Yonglian Sun, Erik Verschueren
Publikováno v:
Immunity. 54(7)
Myeloid cells encounter stromal cells and their matrix determinants on a continual basis during their residence in any given organ. Here, we examined the impact of the collagen receptor LAIR1 on myeloid cell homeostasis and function. LAIR1 was highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d250c4a0d6e640c1597481906772fb59
https://pubmed.ncbi.nlm.nih.gov/34260884
https://pubmed.ncbi.nlm.nih.gov/34260884
Autor:
Jonathan C. Zhao, Jung Kim, Xuesen Dong, Yeqing Angela Yang, Jindan Yu, Hongjian Jin, Yinan Li, Ximing J. Yang
Publikováno v:
Oncogene
Neuroendocrine prostate cancer (NEPC) has increasingly become a clinical challenge. The mechanisms by which neuroendocrine (NE) cells arises from prostate adenocarcinoma cells are poorly understood. FOXA1 is a transcription factor of the forkhead fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16ac1b638853488732ee01ce727eb9a
https://doi.org/10.1038/onc.2017.50
https://doi.org/10.1038/onc.2017.50