Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yeonho Son"'
Autor:
Yoon Keun Cho, Young Cheol Yoon, Hyeonyeong Im, Yeonho Son, Minsu Kim, Abhirup Saha, Cheoljun Choi, Jaewon Lee, Sumin Lee, Jae Hyun Kim, Yun Pyo Kang, Young-Suk Jung, Hong Koo Ha, Je Kyung Seong, James G. Granneman, Sung Won Kwon, Yun-Hee Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Dysregulation of plasmalogen metabolism in adipose tissue is associated with metabolic diseases. Here the authors characterize the role of adipocyte TMEM86A as a lysoplasmalogenase and show its deletion is protective against high fat diet induced met
Externí odkaz:
https://doaj.org/article/2c56b34324264a9f91f13814bde9ec28
Publikováno v:
Nutrition & Metabolism, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Adipose tissue thermogenesis is a potential therapeutic target to increase energy expenditure and thereby combat obesity. The aim of the present study was to investigate the thermogenic and anti-obesity effects of heat-transformed
Externí odkaz:
https://doaj.org/article/63b17b96cd6d48a8aed0df0808fa785f
Autor:
Yeonho Son, Cheoljun Choi, Cheol Song, Hyeonyeong Im, Yoon Keun Cho, Ju Seung Son, Sungug Joo, Yoonjoe Joh, Young Jae Lee, Je Kyung Seong, Yun-Hee Lee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Cell death-inducing DNA fragmentation factor-like effector A (CIDEA) is a lipid droplet-associated protein and is a known marker of the thermogenic capacity of brown/beige adipocytes. To monitor the expression of CIDEA in live mice in a non-
Externí odkaz:
https://doaj.org/article/b8ad4613a74f4a8b8b944e3624538d61
MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling
Autor:
Yoon Keun Cho, Yeonho Son, Sang-Nam Kim, Hyun-Doo Song, Minsu Kim, Ji-Hyun Park, Young-Suk Jung, Sang-Yeop Ahn, Abhirup Saha, James G. Granneman, Yun-Hee Lee
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 86-98 (2019)
Objective: This study investigated the role of microRNAs generated from adipose tissue macrophages (ATMs) during adipose tissue remodeling induced by pharmacological and nutritional stimuli. Methods: Macrophage-specific Dicer knockout (KO) mice were
Externí odkaz:
https://doaj.org/article/9ca3c8ec8d104219b3a36053a453e9d7
Autor:
Yeonho Son, Yoon Keun Cho, Abhirup Saha, Hyun-Jung Kwon, Ji-Hyun Park, Minsu Kim, Young-Suk Jung, Sang-Nam Kim, Cheoljun Choi, Je-Kyung Seong, Rayanne B. Burl, James G. Granneman, Yun-Hee Lee
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp - (2020)
Objective: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present
Externí odkaz:
https://doaj.org/article/82166b24af1f4c1a8349cf9455e1c9c9
Autor:
Cheoljun Choi, Hyun-Doo Song, Yeonho Son, Yoon Keun Cho, Sang-Yeop Ahn, Young-Suk Jung, Young Cheol Yoon, Sung Won Kwon, Yun-Hee Lee
Publikováno v:
Nutrients, Vol 12, Iss 10, p 3072 (2020)
Epigallocatechin-3-gallate (EGCG) is a primary bioactive phytochemical in green tea. Its therapeutic potential in metabolic diseases has been reported; however, the molecular mechanisms of the anti-obesity effect of EGCG have not been fully elucidate
Externí odkaz:
https://doaj.org/article/497afa1c18a34ae18910a9be101c49f6
Autor:
Minsu Kim, Seowoo Im, Yoon keun Cho, Cheoljun Choi, Yeonho Son, Doyoung Kwon, Young-Suk Jung, Yun-Hee Lee
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1394 (2020)
Soy isoflavones are bioactive phytoestrogens with known health benefits. Soybean embryo extract (SEE) has been consumed as a source of isoflavones, mainly daidzein, glycitein, and genistein. While previous studies have reported the anti-obesity effec
Externí odkaz:
https://doaj.org/article/145e4dc5831e4d28ba7734b8d26ad73a
Autor:
Kyungmin Kim, Hyeonyeong Im, Yeonho Son, Minjae Kim, Sushil Kumar Tripathi, Lak Shin Jeong, Yun-Hee Lee
Publikováno v:
International Journal of Obesity. 46:2128-2136
Background and objectives A2A adenosine receptor (A2AAR)-mediated signaling in adipose tissues has been investigated as a potential target for obesity-related metabolic diseases. LJ-4378 has been developed as a dual-acting ligand with A2AAR agonist a
Publikováno v:
Thermogenic Fat ISBN: 9781071631669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1cb7462f5f00e4d68aba85ab401a3bf
https://doi.org/10.1007/978-1-0716-3167-6_14
https://doi.org/10.1007/978-1-0716-3167-6_14
Autor:
Juhyeong Han, Young Suk Jung, Ji Hyun Park, Abhirup Saha, James G. Granneman, Minsu Kim, Jeanho Yun, Sangkyu Lee, Cheoljun Choi, Kyung-Min Kim, Yeonho Son, Eun Ju Bae, Yoon Keun Cho, Yun Hee Lee, Doeun Kim, Hyeonyeong Im, Mi-Ock Lee, Je Kyung Seong
Publikováno v:
Nature Metabolism. 3:428-441
Obesity reduces adipocyte mitochondrial function, and expanding adipocyte oxidative capacity is an emerging strategy to improve systemic metabolism. Here, we report that serine/threonine-protein kinase 3 (STK3) and STK4 are key physiological suppress