Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Yeongjin Hong"'
Autor:
Dinh-Huy Nguyen, Sung-Hwan You, Hien Thi-Thu Ngo, Khuynh Van Nguyen, Khang Vuong Tran, Tan-Huy Chu, So-young Kim, Sang-Jun Ha, Yeongjin Hong, Jung-Joon Min
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Synergistic combinations of immunotherapeutic agents can improve the performance of anti-cancer therapies but may lead to immune-mediated adverse effects. These side-effects can be overcome by using a tumor-specific delivery system. Here, we
Externí odkaz:
https://doaj.org/article/b576ac3584e64476b87361f24f3c58bb
Autor:
Seunghyun Kim, Yu-Ri Lee, Haneol Yang, Chan-Hyeok Park, Chan-Seok Yun, Byung-Chun Jang, Yeongjin Hong, Doo-Sang Park
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Probiotics are live microorganisms that provide health benefits when administered in appropriate amounts by improving or restoring the balance of intestinal microbiota. Various functional probiotic products have been developed due to the growing inte
Externí odkaz:
https://doaj.org/article/cbe3cf93e84a4f6fbfa26160ce26e594
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-5 (2023)
Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic biology, which aims to regulate bacterial growth and gene expr
Externí odkaz:
https://doaj.org/article/19f71580da5b471e996dbe3214b7d244
Publikováno v:
Biosensors, Vol 13, Iss 2, p 266 (2023)
Recent progress in synthetic biology has enabled bacteria to respond to specific disease signals to perform diagnostic and/or therapeutic tasks. Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) colonization of tumors results i
Externí odkaz:
https://doaj.org/article/f5c0e51c48a34c3683a7a8a9581b907e
Autor:
Duck Woong Park, Sun-Hee Kim, Jung Wook Park, Min-Ji Kim, Sun Ju Cho, Hye Jung Park, So Hyang Jung, Mi Hee Seo, Yong Seok Lee, Byung Hee Kim, Hyeran Min, Su Ya Lee, Dong Ryong Ha, Eun Sun Kim, Yeongjin Hong, Jae Keun Chung
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 4, Pp 658-661 (2017)
The incidence rate for scarlet fever in South Korea is rising. During 2008–2015, we collected group A Streptococcus isolates and performed emm and exotoxin genotyping and disk-diffusion antimicrobial tests. Scarlet fever in South Korea was most clo
Externí odkaz:
https://doaj.org/article/80df0bc59ed9488cbffc12c61ee9a7df
Autor:
Min-A Kim, Hee Seung Yoon, Seung-Hwan Park, Dong-Yeon Kim, Ayoung Pyo, Hyeon Sik Kim, Jung-Joon Min, Yeongjin Hong
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180786 (2017)
In a previous study, we developed an E1 monobody specific for the tumor biomarker hEphA2 [PLoS ONE (2015) 10(7): e0132976]. E1 showed potential as a molecular probe for in vitro and in vivo targeting of cancers overexpressing hEphA2. In the present s
Externí odkaz:
https://doaj.org/article/9c886572a2a646aab1c1d0246a8dd5af
Autor:
Kwangsoo Kim, Jae Ho Jeong, Daejin Lim, Yeongjin Hong, Hyung-Ju Lim, Geun-Joong Kim, So-ra Shin, Je-Jung Lee, Misun Yun, Robert A Harris, Jung-Joon Min, Hyon E Choy
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
Bacteria can be engineered to deliver anticancer proteins to tumors via a controlled expression system that maximizes the concentration of the therapeutic agent in the tumor. L-asparaginase (L-ASNase), which primarily converts asparagine to aspartate
Externí odkaz:
https://doaj.org/article/3c08b86bee9840319cb46a8d07a448b4
Autor:
Seung-Hwan Park, Sukho Park, Dong-Yeon Kim, Ayoung Pyo, Richard H Kimura, Ataya Sathirachinda, Hyon E Choy, Jung-Joon Min, Sanjiv Sam Gambhir, Yeongjin Hong
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132976 (2015)
Monobodies are binding scaffold proteins originating from a human fibronectin domain III (Fn3) scaffold that can be easily engineered with specificity and affinity. Human EphA2 (hEphA2) is an early detection marker protein for various tumors includin
Externí odkaz:
https://doaj.org/article/24cf4a55cd474f5ea17afe87e2077416
Autor:
Jae-Ho Jeong, Kwangsoo Kim, Daejin Lim, Kwangjoon Jeong, Yeongjin Hong, Vu H Nguyen, Tae-Hyoung Kim, Sangryeol Ryu, Jeong-A Lim, Jae Il Kim, Geun-Joong Kim, Sun Chang Kim, Jung-Joon Min, Hyon E Choy
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e80050 (2014)
Bacterial cancer therapy relies on the fact that several bacterial species are capable of targeting tumor tissue and that bacteria can be genetically engineered to selectively deliver therapeutic proteins of interest to the targeted tumors. However,
Externí odkaz:
https://doaj.org/article/023e15b7802e47c0a85d3e13e17cc3a9
Autor:
Kwangsoo Kim, Jae Ho Jeong, Daejin Lim, Yeongjin Hong, Misun Yun, Jung-Joon Min, Sahng-June Kwak, Hyon E Choy
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60511 (2013)
During the last decade, an increasing number of papers have described the use of various genera of bacteria, including E. coli and S. typhimurium, in the treatment of cancer. This is primarily due to the facts that not only are these bacteria capable
Externí odkaz:
https://doaj.org/article/737876c5c73f44a792979f860102b883