Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yeong-Gwan Park"'
Autor:
Yeong-Gwan Park, Yoshiharu Tanaka, Tsuneo Megumi, Ichiro Uchida, Chang-Woo Song, Masaaki Okumoto
Publikováno v:
Journal of Anesthesia. 18:267-276
We attempted to identify the locations of major mouse genes responsible for sensitivity to diethylether (ether) anesthesia, using microsatellite linkage analyses including Quantitative Trait Locus (QTL) analysis.To determine the locations of ether an
Autor:
Yeong-Gwan Park, Michael T. Debies, Danny R. Welch, Howard H. Yang, Kent W. Hunter, Maxwell P. Lee, Luanne Lukes, Rajeev S. Samant
Publikováno v:
Mammalian Genome. 13:289-292
Comparative genomics has recently become a significant tool in the study of mammalian genomes. The completion of the human genome sequence and the increasing amounts of publicly available mouse and rat high throughput sequence have enabled identifica
Autor:
Shizu Hayasaka, Yoshiko Takagishi, Sen-ichi Oda, Masaaki Okumoto, Minoru Inouye, Yeong-Gwan Park
Publikováno v:
Experimental Animals. 50:179-182
Pelage skin of C3H/HeJ mice homozygous at an autosomal recessive mutant locus, rough fur (ruf) which is located on chromosome 9, was histologically analyzed. Sebaceous glands synthesizing lipids were larger in the mutant mice than in controls in an e
Publikováno v:
Cancer Letters. 148:95-103
Recent genetic studies of tumorigenesis have strongly suggested an existence of tumor suppressor gene(s) on murine chromosome 12 and human chromosome 14q32. We previously described that putative tumor suppressor gene(s) might reside between D12Mit53
Autor:
Haiyan Yang, Yeong-Gwan Park, Ying Shi, Kent W. Hunter, Luanne Lukes, Jessica Rouse, Mindy Lancaster, Timothy D. Veenstra, Ming Zhou
Publikováno v:
Clinicalexperimental metastasis. 21(8)
A significant fraction of cancer patients have occult disseminated tumors at the time of primary diagnosis, which usually progress to become clinically relevant lesions. Since the majority of cancer mortality is associated with metastatic disease, th
Autor:
Mindy Lancaster, Kent W. Hunter, Douglas R. Lowy, Xiaohong Zhao, Paul D.P. Pharoah, Xiaolan Qian, Yeong-Gwan Park, Fabienne Lesueur
Publikováno v:
Nature genetics. 37(10)
Previously, using an inbred strain screen and QTL mapping strategies, we demonstrated the presence of loci in the mouse genome that significantly influenced the ability of a transgene-induced mammary tumor to metastasize to the lung. Here we present
Autor:
Masaaki Okumoto, Chang-Woo Song, Yeong-Gwan Park, Seiichi Umesako, Doo-Pyo Hong, Shiro Aizawa, Nobuko Mori
Publikováno v:
Journal of radiation research. 43(2)
Lymphoma / Loss of heterozygosity (LOH), Tumor suppressor gene / p53 / Mouse Regions of allelic loss on chromosomes in many tumors of human and some experimental animals are generally considered to harbor tumor-suppressor genes involved in tumorigene
Autor:
Makiko Ishibashi, Chang-Woo Song, Yasuo Matsumoto, Kenjiro Tabata, Masaaki Okumoto, Ryo Kominami, Kozaburo Esaki, Yasuhiko Takamori, Yeong-Gwan Park, Nobuko Mori
Publikováno v:
Molecular carcinogenesis. 22(3)
Analyses of genetic alterations in tumors from F1 hybrid mice produced by inter-subspecific crosses between genetically well-characterized inbred strains provide precise and comprehensive evidence for genetic abnormalities such as allelic loss. We pe