Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yeon Hee Kook"'
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Calcium ions (Ca2+) play pivotal roles in regulating diverse brain functions, including cognition, emotion, locomotion, and learning and memory. These functions are intricately regulated by a variety of Ca2+-dependent cellular processes, enc
Externí odkaz:
https://doaj.org/article/d6a1b78b16564f3da613eeb823b102d2
Autor:
Palsamy Periyasamy, Shannon Callen, Fang Niu, Ke Liao, Yeon Hee Kook, Shilpa Buch, Minglei Guo
Publikováno v:
Molecular Neurobiology. 55:3196-3210
Cocaine is known to activate microglia both in vitro and in vivo. High expression of microglial Toll-like receptors (TLRs) and their downstream signal transducers play critical roles in determining microglial activation status. Emerging reports have
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 4, Iss 1, Pp 1-13 (2018)
Cell Death Discovery, Vol 4, Iss 1, Pp 1-13 (2018)
The incidence of pulmonary arterial hypertension (PAH) is a significant co-morbidity observed in HIV (+) individuals. Pulmonary artery smooth muscle cells (PASMCs)—key components of the arterial vessel wall that regulate vessel diameter, demonstrat
Autor:
Yeon Hee Kook, Minglei Guo, Fang Niu, Shilpa Buch, Ke Liao, Palsamy Periyasamy, Shannon Callen
Neuroinflammation plays a critical role in the development of reward-related behavior in cocaine self-administration rodents. Cocaine, one of most commonly abused drugs, has been shown to activate microglia both in vitro and in vivo. Detailed molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a1a64637ea30a09f209e72b7e08536
https://europepmc.org/articles/PMC5221603/
https://europepmc.org/articles/PMC5221603/
Publikováno v:
Cell Death & Disease
Cocaine is a highly addictive narcotic associated with dendritic spine plasticity in the striatum. However, it remains elusive whether cocaine modifies spines in a cell type-specific or region-specific manner or whether it alters different types of s
Publikováno v:
Biochemical and Biophysical Research Communications. 411:370-374
The hematopoietic cytokines erythropoietin (Epo) and granulocyte-colony stimulating factor (G-CSF) provide neuroprotection in several in vitro and in vivo models of Parkinson's disease (PD). The molecular mechanism by which Epo and G-CSF signals redu
Autor:
Yeon Hee Kook, Hyewon Youn, Eun Kyung Choi, Eun-Taex Oh, Chulhee Kim, Byung Uk Lim, Heon Joo Park, Seong-Yun Jeong
Publikováno v:
International Journal of Radiation Biology. 85:167-174
To determine the efficacy of a caffeine derivative 1-methylxanthine (1-MTX) in increasing radiosensitivity of cancer cells and elucidate the underlying mechanisms in vitro.RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53) were
Block copolymer micelles conjugated with anti-EGFR antibody for targeted delivery of anticancer drug
Autor:
Taiho Noh, Eun Kyung Choi, Chiyoung Park, Heon Joo Park, Hana Kim, Eun Tax Oh, Chulhee Kim, Yeon Hee Kook, Hyewon Youn
Publikováno v:
Journal of Polymer Science Part A: Polymer Chemistry. 46:7321-7331
Antiepidermal growth factor receptor antibody (anti-EGFR antibody) was conjugated with the block copolymer micelle based on poly(ethylene glycol) (PEG) and poly(e-caprolactone) (PCL) for active targeting to EGFR overexpressing cancer cells. Doxorubic
Autor:
Kaoru Terai, Heon Joo Park, Yeon Hee Kook, Doo Sung Lee, David A. Boothman, Jin-Seok Kim, Kyung Hwa Park, In-Mi Ji, Robert J. Griffin, Byung U. Lim, Chang W. Song, Eun Tax Oh, Eun Kyung Choi, Melissa L. Loren
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 8, Pp 634-642 (2007)
We found that (β-Lapachone ((β-Lap), a novel bioreductive drug, caused rapid apoptosis, clonogenic cell death in A549 human lung epithelial cancer cells in vitro in a dose-dependent manner. The clonogenic cell death caused by (β-Lap could be signi
Autor:
So Ryung Lee, Eun Kyung Choi, In Mi Ji, Robert J. Griffin, C. W. Song, Jin-Seok Kim, Byung Uk Lim, Yeon Hee Kook, Heon Joo Park, Doo Sung Lee
Publikováno v:
International Journal of Radiation Biology. 82:277-283
To elucidate the relationship between the radiation-induced activation of ataxia telangiectasia mutated (ATM) kinase, G2 arrest and the caffeine-induced radiosensitization.RKO cells (human colorectal cancer cells) and ATM kinase over-expressing RKO/A