Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yenyun Wang"'
Autor:
James W. Crawford, Beverly A. Teicher, Terence S. Herman, Yenyun Wang, M. Raphael Pfeffer, Sylvia A. Holden, Emil Frei
Publikováno v:
Science. 247:1457-1461
EMT-6 murine mammary tumors were made resistant to cis-diamminedichloroplatinum (II) (CDDP), carboplatin, cyclophosphamide (CTX), or thiotepa in vivo by treatment of tumor-bearing animals with the drug during a 6-month period. In spite of high levels
Autor:
Ch. Van Den Eynde, Stuart Bloor, Gary Tarpley, William W. Freimuth, Wanda Decian, Brendan Larder, Kurt Hertogs, Yenyun Wang
Publikováno v:
AIDS (London, England). 14(13)
Objective: Although the use of HIV-1 protease inhibitors (PI) has substantially benefited HIV-1-infected individuals, new PI are urgently needed, as broad PI resistance and therapy failure is common. Methods: The antiviral activity of tipranavir (TPV
Autor:
J. Zhu, Anantbhushan Ranade, P. M. Parikh, Ashok K. Vaid, Suresh H. Advani, Ajay Bapna, Rajesh K. Malik, Yenyun Wang, P. M. Ismail
Publikováno v:
Journal of Clinical Oncology. 29:7569-7569
7569 Background: Talactoferrin alfa (TLF), a novel immunomodulatory agent, has demonstrated anti-tumor activity in two randomized, placebo-controlled phase II studies in NSCLC, including a 100-pati...
Autor:
Yenyun Wang, Rajesh K. Malik, Atul Varadhachary, J. Engelmeyer, Raghunadharao Digumarti, M. Fodor, K. Petrak, Teresa G. Hayes
Publikováno v:
Journal of Clinical Oncology. 26:3080-3080
3080 Background: TLF is a novel dendritic cell (DC) activating drug with clinical activity in NSCLC and other cancers. Orally administered TLF binds gut epithelium, is transported into the Gut Associated Lymphoid Tissue, recruits circulating immature
Autor:
Jayaprakash Madhavan, D. Raghunadharao, Suresh H. Advani, Anantbhushan Ranade, Shona Nag, P. K. Parikh, Ashok K. Vaid, Yenyun Wang, Atul Varadhachary
Publikováno v:
Journal of Clinical Oncology. 25:7540-7540
7540 Background: Talactoferrin alfa (TLF), an immunomodulatory protein with a novel anti-cancer mechanism of action, was active preclinically and in non-small cell lung cancer (NSCLC) patients in Phase 1b studies. Randomized Phase 2 studies in NSCLC
Autor:
Suresh H. Advani, Yenyun Wang, P. M. Parikh, S. Patil, Jayaprakash Madhavan, Atul Varadhachary, D. Raghunadharao, Shona Nag, Pramod Kumar Julka, Dinesh Chandra Doval, G. Raman
Publikováno v:
Journal of Clinical Oncology. 24:7095-7095
7095 Background: Talactoferrin alfa (TLF) is an oral immunomodulatory protein with a novel mechanism. TLF showed preclinical anti-cancer activity alone and in combination with chemotherapy. In Phase I/II trials, TLF was safe with apparent single-agen
Autor:
Patton Jd, Jia-Ling Yang, J. Justin McCormick, Ann E. Aust, Yenyun Wang, Nitai P. Bhattacharyya, Veronica M. Maher, Li L. Yang
Publikováno v:
Environmental Health Perspectives
Metabolites of two structurally related chemical carcinogens, benzo[a]pyrene and 1-nitropyrene, were compared for their ability to cause cytotoxicity and induce mutations in normally repairing or nucleotide excision repair-deficient diploid human fib
Publikováno v:
Mutation Research Letters. 175:107-114
Retinoblastoma (RB) is a cancer of the retina which characteristically occurs in early childhood. Bilateral RB is an inherited form of this disease. Such patients are at greatly increased risk of subsequently developing second tumors in mesenchymal t
Autor:
Jayaprakash Madhavan, Ajay Bapna, Purvish M. Parikh, Pramod Kumar Julka, Shona Nag, Ganapathi Raman, Shekhar Patil, Suresh H. Advani, Annantbhushan A. Ranade, Raghunadharao Digumarti, Rajesh K. Malik, Dinesh C. Doval, Yenyun Wang, Atul Varadhachary
Publikováno v:
Journal of Thoracic Oncology. (6):1098-1103
Introduction: The aim of the study is to investigate the activity and safety of oral talactoferrin (TLF) plus carboplatin and paclitaxel (C/P) in patients with previously untreated stage IIIB/IV non-small cell lung cancer. Methods: Patients ( n = 110
Publikováno v:
Carcinogenesis. 7:1927-1929
Retinoblastoma (RB), cancer of the retina, occurs in an inherited form which not only predisposes the patient to bilateral RB, but also to the risk of developing secondary tumors of mesenchymal origin (osteosarcomas and fibrosarcomas). These tumors o