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Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells

Autor: Kacimi, R, Yenari, MA

Publikováno v: Glia, vol 63, iss 7
Kacimi, R; & Yenari, MA. (2015). Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells. GLIA, 63(7), 1200-1212. doi: 10.1002/glia.22811. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/89d223fk

© 2015 Wiley Periodicals, Inc. The inhibition of the 90-kDa heat shock protein (HSP90) leads to upregulation of the 70-kDa-inducible HSP70. HSP70 has been previously shown to be neuroprotective and anti-inflammatory. Geldanamycin (GA) and other HSP9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::072e7e2c1567b009f0d0b70fd3773a01
https://escholarship.org/uc/item/89d223fk

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Microglial P2Y12 Deficiency/Inhibition Protects against Brain Ischemia

Autor: Webster, CM, Hokari, M, McManus, A, Tang, XN, Ma, H, Kacimi, R, Yenari, MA

Publikováno v: Webster, CM; Hokari, M; McManus, A; Tang, XN; Ma, H; Kacimi, R; et al.(2013). Microglial P2Y12 Deficiency/Inhibition Protects against Brain Ischemia. PLoS ONE, 8(8). doi: 10.1371/journal.pone.0070927. UCSF: Retrieved from: http://www.escholarship.org/uc/item/98p4b2q3

Objective:Microglia are among the first immune cells to respond to ischemic insults. Triggering of this inflammatory response may involve the microglial purinergic GPCR, P2Y12, activation via extracellular release of nucleotides from injured cells. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::03f6e92991f87bac3f4c128576c87530
http://www.escholarship.org/uc/item/98p4b2q3

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Influence of therapeutic hypothermia on regeneration after cerebral ischemia

Autor: Yenari, MA, Han, HS

Publikováno v: Yenari, MA; & Han, HS. (2013). Influence of therapeutic hypothermia on regeneration after cerebral ischemia. Frontiers of Neurology and Neuroscience, 32, 122-128. doi: 10.1159/000346428. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/39z3v10w
Frontiers of neurology and neuroscience, vol 32

Copyright © 2013 S. Karger AG, Basel. The protective effect of therapeutic hypothermia in cerebral ischemia is well accepted in experimental models, and some clinical studies show that there is benefit in humans as well. Long-term observations in an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8e075a3617dfed92eb2f82643e694d7e
http://www.escholarship.org/uc/item/39z3v10w

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Temperature affects thrombolytic efficacy using rt-Pa and eptifibatide, an in vitro study: editorial commentary on Meunier et al., 2012

Autor: Yenari, MA

Publikováno v: Therapeutic hypothermia and temperature management, vol 2, iss 4
Yenari, MA. (2012). Temperature affects thrombolytic efficacy using rt-Pa and eptifibatide, an in vitro study: editorial commentary on Meunier et al., 2012.. Therapeutic hypothermia and temperature management, 2(4), 166. doi: 10.1089/ther.2012.0020. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1996m6n8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::25cabcb4fbce498e8351a29139b5990f
https://escholarship.org/uc/item/1996m6n8

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