Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yen-Lurk Lee"'
Autor:
Heng Lin, Yen-Sung Huang, Jean-Michel Fustin, Masao Doi, Huatao Chen, Hui-Huang Lai, Shu-Hui Lin, Yen-Lurk Lee, Pei-Chih King, Hsien-San Hou, Hao-Wen Chen, Pei-Yun Young, Hsu-Wen Chao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Polyploidy is a common feature in normal hepatocytes, however, the pathophysiological function of hepatic hyperpolyploidy is unclear. Here, the authors show that genotoxic stress induces accumulation of hyperpolyploid hepatocytes around the centrilob
Externí odkaz:
https://doaj.org/article/2a6b0a8610cd4b32b27ac9dde0bc48ce
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108269- (2020)
Summary: Eukaryotic mRNAs are 5′ end capped with a 7-methylguanosine, which is important for processing and translation of mRNAs. Cap methyltransferase 1 (CMTR1) catalyzes 2′-O-ribose methylation of the first transcribed nucleotide (N1 2′-O-Me)
Externí odkaz:
https://doaj.org/article/62072538263a4dac914fb3917585f521
Autor:
Bo-Jeng Wang, Hsinyu Lee, Wen-Ming Hsu, Yi-Shuian Huang, Yun Wen Chen, Yung-Feng Liao, Ding I. Yang, Yen-Lurk Lee, Po-Fan Wu, Noopur Bhore
Publikováno v:
Molecular Neurobiology. 58:2204-2214
Dual-specificity phosphatases (DUSPs) comprise a unique group of enzymes that dephosphorylate signaling proteins at both phospho-serine/threonine and phospho-tyrosine residues. Since Notch signaling is an essential pathway for neuronal cell fate dete
Autor:
Jean-Michel Fustin, Hao Wen Chen, Masao Doi, Hsu Wen Chao, Pei Yun Young, Hsien San Hou, Shu Hui Lin, Huatao Chen, Pei Chih King, Yen Lurk Lee, Yen Sung Huang, Hui Huang Lai, Heng Lin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, pp. 645 . https://doi.org/10.1038/s41467-020-20572-8
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, Lee, Y-L, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, 645 . https://doi.org/10.1038/s41467-020-20572-8
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, pp. 645 . https://doi.org/10.1038/s41467-020-20572-8
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, Lee, Y-L, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, 645 . https://doi.org/10.1038/s41467-020-20572-8
Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for tumor foci emergence is and how this tra
Autor:
Hao-Wen Chen, Pei-Chih King, Huatao Chen, Yen-Lurk Lee, Pei-Yun Young, Yen Sung Huang, Hsu Wen Chao, Hui-Huang Lai, Heng Lin, Hsien-San Hou, Shu Hui Lin, Masao Doi, Jean-Michel Fustin
Publikováno v:
Fustin, J-M & Chao, H-W 2020, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', bioRxiv . https://doi.org/10.1101/2020.08.23.258699
Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for tumor foci emergence is and how this tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954ccd8e4a6f19dab60dc3b0b9367502
https://doi.org/10.1101/2020.08.23.258699
https://doi.org/10.1101/2020.08.23.258699
Autor:
Noopur, Bhore, Bo-Jeng, Wang, Po-Fan, Wu, Yen-Lurk, Lee, Yun-Wen, Chen, Wen-Ming, Hsu, Hsinyu, Lee, Yi-Shuian, Huang, Ding-I, Yang, Yung-Feng, Liao
Publikováno v:
Molecular neurobiology. 58(5)
Dual-specificity phosphatases (DUSPs) comprise a unique group of enzymes that dephosphorylate signaling proteins at both phospho-serine/threonine and phospho-tyrosine residues. Since Notch signaling is an essential pathway for neuronal cell fate dete
Autor:
Wen-Ming Hsu, Yi-Shuian Huang, Ju Yun Chou, Po Fan Wu, Hsinyu Lee, Noopur Bhore, Pei Yi Wu, Yen Lurk Lee, Pei Jung Lu, Yun Wen Chen, Yung-Feng Liao
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(9)
Alzheimer's disease (AD) is characterized by a chronic decline in cognitive function and is pathologically typified by cerebral deposition of amyloid-β peptide (Aβ). The production of Aβ is mediated by sequential proteolysis of amyloid precursor p
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108269-(2020)
Cell Reports
Cell Reports
Eukaryotic mRNAs are 5′ end capped with a 7-methylguanosine, which is important for processing and translation of mRNAs. Cap methyltransferase 1 (CMTR1) catalyzes 2′-O-ribose methylation of the first transcribed nucleotide (N1 2′-O-Me) to mask
Autor:
Po-Fan Wu, Bhore, Noopur, Yen-Lurk Lee, Ju-Yun Chou, Yun-Wen Chen, Pei-Yi Wu, Wen-Ming Hsu, Hsinyu Lee, Yi-Shuian Huang, Pei-Jung Lu, Yung-Feng Liao
Publikováno v:
FASEB Journal; Sep2020, Vol. 34 Issue 9, p12127-12146, 20p