Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Yen-Hui C"'
Autor:
Ya-Hui Lin, Li-Wen Wang, Yen-Hui Chen, Yi-Chieh Chan, Shang-Hsiu Hu, Sheng-Yan Wu, Chi-Shiun Chiang, Guan-Jie Huang, Shang-Da Yang, Shi-Wei Chu, Kuo-Chuan Wang, Chin-Hsien Lin, Pei-Hsin Huang, Hwai-Jong Cheng, Bi-Chang Chen, Li-An Chu
Publikováno v:
eLife, Vol 13 (2024)
Tissue-clearing and labeling techniques have revolutionized brain-wide imaging and analysis, yet their application to clinical formalin-fixed paraffin-embedded (FFPE) blocks remains challenging. We introduce HIF-Clear, a novel method for efficiently
Externí odkaz:
https://doaj.org/article/b239d423825a47b49f63a520e73a8d68
Autor:
I-Jung Lee, Yu-Hua Lan, Ping-Yi Wu, Yan-Wei Wu, Yu-Hung Chen, Sheng-Che Tseng, Tzu-Jiun Kuo, Cheng-Pu Sun, Jia-Tsrong Jan, Hsiu-Hua Ma, Chun-Che Liao, Jian-Jong Liang, Hui-Ying Ko, Chih-Shin Chang, Wen-Chun Liu, Yi-An Ko, Yen-Hui Chen, Zong-Lin Sie, Szu-I Tsung, Yi-Ling Lin, I-Hsuan Wang, Mi-Hua Tao
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTNumerous vaccines have been developed to address the current COVID-19 pandemic, but safety, cross-neutralizing efficacy, and long-term protectivity of currently approved vaccines are still important issues. In this study, we developed a subun
Externí odkaz:
https://doaj.org/article/b226ffaca06841fa8ad7defca441cd0e
Autor:
Cheng-Yu Tsai, Ying-Chang Lu, Yen-Hui Chan, Navaneethan Radhakrishnan, Yuan-Yu Chang, Shu-Wha Lin, Tien-Chen Liu, Chuan-Jen Hsu, Pei-Lung Chen, Lee-Wei Yang, Chen-Chi Wu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5698-5711 (2023)
Variants in the gap junction beta-2 (GJB2) gene are the most common cause of hereditary hearing impairment. However, how GJB2 variants lead to local physicochemical and structural changes in the hexameric ion channels of connexin 26 (Cx26), resulting
Externí odkaz:
https://doaj.org/article/4cc6f64e81f44b9c8a1e0e677fb5c287
Autor:
Yen-Hui Chan, Cheng-Yu Tsai, Chang-Han Ho, Ying-Chang Lu, Pei-Hsuan Lin, Ta-Ching Chen, You-Tzung Chen, Cheng-Yen Huang, Tien-Chen Liu, Chuan-Jen Hsu, Chen-Chi Wu
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103068- (2023)
Pathogenic variants of the WFS1 gene can cause recessive-inherited Wolfram syndrome or dominant-inherited Wolfram-like syndrome with optic atrophy and hearing impairment. Using the Sendai virus delivery system, we generated induced pluripotent stem c
Externí odkaz:
https://doaj.org/article/49e3de1a76214919a0162b874dcd28f8
Autor:
Wei Shin Chou, Yu Ming Shiao, Jia Shing Chen, Ju Chin Tsauer, Yi Fen Chang, Yen-Hui Chiu, Ching Hua Hsiao
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 61, Iss 3, Pp 510-513 (2022)
Objective: To precision survey a fetal congenital primary aphakia molecular etiology. Case report: A case of 42 years old pregnancy woman prenatal diagnostic examination by amniocentesis conducted at 17 weeks' gestation and demonstrated a normal fema
Externí odkaz:
https://doaj.org/article/125cdae32f3b4a60b9613fb3660733aa
Autor:
Chin-Ju Hu, Ying-Chang Lu, Cheng-Yu Tsai, Yen-Hui Chan, Pei-Hsuan Lin, Yi-Shan Lee, I.-Shing Yu, Shu-Wha Lin, Tien-Chen Liu, Chuan-Jen Hsu, Ting-Hua Yang, Yen-Fu Cheng, Chen-Chi Wu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Recessive variants of the SLC26A4 gene are an important cause of hereditary hearing impairment. Several transgenic mice with different Slc26a4 variants have been generated. However, none have recapitulated the auditory phenotypes in humans.
Externí odkaz:
https://doaj.org/article/39c68a982910479db6b294bf68ba68ea
Autor:
Yen-Hui Chan, Chang-Han Ho, Cheng-Yu Tsai, Ying-Chang Lu, Pei-Hsuan Lin, Ta-Ching Chen, You-Tzung Chen, Cheng-Yen Huang, Tien-Chen Liu, Chuan-Jen Hsu, Chen-Chi Wu
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102903- (2022)
Pathogenic variants of OPA1 have been associated with autosomal dominant optic atrophy (DOA), leading to optic, auditory, and other sensorineural neuropathies and myopathies. Using the Sendai virus delivery system, we generated induced pluripotent st
Externí odkaz:
https://doaj.org/article/44d5b4e1264b482692fd96e5abebf0b1
Autor:
Chia-En Lien, Yi-Jiun Lin, Charles Chen, Wei-Cheng Lian, Tsun-Yung Kuo, John D. Campbell, Paula Traquina, Meei-Yun Lin, Luke Tzu-Chi Liu, Ya-Shan Chuang, Hui-Ying Ko, Chun-Che Liao, Yen-Hui Chen, Jia-Tsrong Jan, Hsiu-Hua Ma, Cheng-Pu Sun, Yin-Shiou Lin, Ping-Yi Wu, Yu-Chiuan Wang, Mi-Hua Tao, Yi-Ling Lin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract The COVID-19 pandemic presents an unprecedented challenge to global public health. Rapid development and deployment of safe and effective vaccines are imperative to control the pandemic. In the current study, we applied our adjuvanted stable
Externí odkaz:
https://doaj.org/article/97e4b89a509c4a8585861a8a1abe0884
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 5, Pp 916-922 (2020)
Drug lag—delayed approval or reimbursement—is a major barrier to accessing cutting‐edge drugs. Unlike approval lag, reimbursement lag is under‐researched. We investigated the key determinants of reimbursement lag under Taiwan National Health
Externí odkaz:
https://doaj.org/article/e1ddebf6d9ee4a57aee0b003ea8b4737
Autor:
Cheng-Pu Sun, Jia-Tsrong Jan, I-Hsuan Wang, Hsiu-Hua Ma, Hui-Ying Ko, Ping-Yi Wu, Tzu-Jiun Kuo, Hsin-Ni Liao, Yu-Hua Lan, Zong-Lin Sie, Yen-Hui Chen, Yi-An Ko, Chun-Che Liao, Liang-Yu Chen, I-Jung Lee, Szu-I Tsung, Yun-Ju Lai, Ming-Tsai Chiang, Jian-Jong Liang, Wen-Chun Liu, Jing-Rong Wang, Joyce Pei-Yi Yuan, Yin-Shiou Lin, Yi-Ching Tsai, Shie-Liang Hsieh, Chia-Wei Li, Han-Chung Wu, Tai-Ming Ko, Yi-Ling Lin, Mi-Hua Tao
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009758 (2021)
Since the pandemic of COVID-19 has intensely struck human society, small animal model for this infectious disease is in urgent need for basic and pharmaceutical research. Although several COVID-19 animal models have been identified, many of them show
Externí odkaz:
https://doaj.org/article/4c7d04f4f9e34a85ac0d0588129271b2