Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Yen-Hsien Li"'
Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Autor:
Ju-Yi Hsieh, Kun-Chi Chen, Chun-Hsiung Wang, Guang-Yaw Liu, Jie-An Ye, Yu-Tung Chou, Yi-Chun Lin, Cheng-Jhe Lyu, Rui-Ying Chang, Yi-Liang Liu, Yen-Hsien Li, Mau-Rong Lee, Meng-Chiao Ho, Hui-Chih Hung
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Abstract Human mitochondrial NAD(P)+-dependent malic enzyme (ME2) is well-known for its role in cell metabolism, which may be involved in cancer or epilepsy. We present potent ME2 inhibitors based on cyro-EM structures that target ME2 enzyme activity
Externí odkaz:
https://doaj.org/article/8c54706653c84fc5ab3e4d4963ea7c0e
Autor:
Chorpaka Thepthanee, Chan-Chiung Liu, Hsu-Sheng Yu, Ho-Shin Huang, Chia-Hung Yen, Yen-Hsien Li, Maw-Rong Lee, Ean-Tun Liaw
Publikováno v:
Foods, Vol 10, Iss 12, p 2987 (2021)
Black rice leaves (Oryza sativa L.) are a major part of rice straw left in open fields after rice harvest as agricultural waste. In this study, crude ethanolic extract (CEE) and various solvent fractions (hexane (Hex), ethyl acetate (EtOAc), n-butano
Externí odkaz:
https://doaj.org/article/b2866d21abe94216aec6cc875ff3a7fc
Publikováno v:
Mass Spectrometry Reviews.
Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications around the world. The characterization of the phytochemical components in TCMs is very important for studying the therapeutic mechanism of TCMs. In the
Autor:
Chorpaka Thepthanee, Chan-Chiung Liu, Hsu-Sheng Yu, Ho-Shin Huang, Chia-Hung Yen, Yen-Hsien Li, Maw-Rong Lee, Ean-Tun Liaw
Publikováno v:
BioMed research international. 2022
The leaves of black rice, well-known as postharvest agricultural waste, contain a rich source of antioxidants with multiple benefits for human health. In the present study, the ethyl acetate fraction obtained from black rice leaf was separated into f
Autor:
Yu-Nan Huang, Chung-Hsing Wang, Hui-Chih Hung, Shang-Lun Chiang, Yu-Chen Liao, Fuu Jen Tsai, Yen-Hsien Li, Su-Ching Liu, Maw-Rong Lee, Yu-Jung Lin, Pen-Hua Su
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1720, p 1720 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1720, p 1720 (2021)
Volume 22
Issue 4
Long non-coding RNA steroid receptor RNA activators (LncRNA SRAs) are implicated in the β-cell destruction of Type 1 diabetes mellitus (T1D), but functional association remains poorly understood. Here, we aimed to verify the role of LncRNA SRA regul
Autor:
Wen-Yen Chiu, Chih-Yu Kuo, Trong-Ming Don, Chia-Fen Lee, Yen-Hsien Li, I-Ann Lei, Yen-Ting Lin
Publikováno v:
Materials Chemistry and Physics. 206:136-143
This study focused on the importance of the interfacial adhesion in the zirconia (ZrO2)/silicone hybrids as the encapsulating material on the reliability of the LEDs. Surface-modified ZrO2 nanoparticles (m-ZrO2) with functional groups were prepared b
Publikováno v:
Analytica Chimica Acta. 938:98-105
During the electrospray ionization (ESI) process, ions move through a heated capillary aperture to be detected on arrival at a mass analyzer. However, the ESI process creates an ion plume, which expands into an ion cloud with an area larger than that
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1600
Algal toxin is a unique type of toxin generated with harmful algal blooms in water bodies. This phenomenon is worsened by eutrophication caused by excessive discharge of nutrients into surface water bodies. Since algal toxins are hard to remove after
Autor:
Yen-Hsien Li, 李妍嫻
105
In this study, a universal home-made golf ball-assisted electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) for liquid chromatography tandem mass spectrometry (LC-MS/MS) was developed to determine 20 trace amino
In this study, a universal home-made golf ball-assisted electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) for liquid chromatography tandem mass spectrometry (LC-MS/MS) was developed to determine 20 trace amino
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/80353066338896452564
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969562
Algal toxin is a unique type of toxin generated with harmful algal blooms in water bodies. This phenomenon is worsened by eutrophication caused by excessive discharge of nutrients into surface water bodies. Since algal toxins are hard to remove after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2189357678167b1c5c07c94300fef84
https://doi.org/10.1007/978-1-4939-6958-6_8
https://doi.org/10.1007/978-1-4939-6958-6_8