Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yen-Der Li"'
Autor:
Wei-Yu Chi, Yen-Der Li, Hsin-Che Huang, Timothy En Haw Chan, Sih-Yao Chow, Jun-Han Su, Louise Ferrall, Chien-Fu Hung, T.-C. Wu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-27 (2022)
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health challenge in this century. Two years after its emergence, the rapid development and deployment of effective COVID-19 vaccines have successfully controlled this pandem
Externí odkaz:
https://doaj.org/article/e431f00b142448dab4bfa9f2542e0339
Autor:
Charles Zou, Hojong Yoon, Paul M.C. Park, J.J. Patten, Jesse Pellman, Jeannie Carreiro, Jonathan M. Tsai, Yen-Der Li, Shourya S. Roy Burman, Katherine A. Donovan, Jessica Gasser, Adam S. Sperling, Radosław P. Nowak, Eric S. Fischer, Robert A. Davey, Benjamin L. Ebert, Mikołaj Słabicki
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106601- (2023)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hijacks multiple human proteins during infection and viral replication. To examine whether any viral proteins employ human E3 ubiquitin ligases, we evaluated the stability of SARS-
Externí odkaz:
https://doaj.org/article/cb16503b59c14a149316faaa454be17e
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-23 (2020)
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the most challenging pandemic in this century. Considering its high mortality and r
Externí odkaz:
https://doaj.org/article/2ea568c3915240c4a5b88c40e2a63d97
Autor:
Yen-Der Li, 李彥德
102
The characteristics of free-surface profile and air-concentration distribution along a chute flow around an aerator model, both in the sliding jet over air cavity and in the aerated flow right downstream of the wedged tip of air cavity, were
The characteristics of free-surface profile and air-concentration distribution along a chute flow around an aerator model, both in the sliding jet over air cavity and in the aerated flow right downstream of the wedged tip of air cavity, were
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/57314533151306156135
Autor:
Harrison K. Tsai, Tasos Gogakos, Va Lip, Jonathan Tsai, Yen-Der Li, Adam Fisch, Jonathan Weiss, Leslie Grimmett, Thai Hoa Tran, Maxime Caron, Sylvie Langlois, Daniel Sinnett, Yana Pikman, Annette S. Kim, Valentina Nardi, Lewis B. Silverman, Marian H. Harris
Recognition of aberrant gene isoforms indicative of underlying DNA events can impact molecular classification and risk stratification of B lymphoblastic leukemia (B-ALL). Aberrant ERG isoforms have been proposed as markers of the favorable-risk DUX4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c439b5afa1144b5504c187d6dcbc4382
https://doi.org/10.1101/2022.07.29.22278149
https://doi.org/10.1101/2022.07.29.22278149
Autor:
Yen-Der Li, Michelle W. Ma, Muhammad Murtaza Hassan, Kedar Puvar, Mingxing Teng, Brittany Sandoval, Ryan Lumpkin, Scott B. Ficarro, Michelle Y. Wang, Shawn Xu, Brian J. Groendyke, Logan H. Sigua, Isidoro Tavares, Charles Zou, Jonathan M. Tsai, Paul M. Park, Hojong Yoon, Radosław P. Nowak, Jarrod A. Marto, Jun Qi, Katherine A. Donovan, Mikołaj Słabicki, Nathanael S. Gray, Eric S. Fischer, Benjamin L. Ebert
Publikováno v:
Cancer Research. 83:3424-3424
Molecular glue degraders have emerged as a powerful class of small-molecule therapeutics, as demonstrated by the clinical successes of thalidomide analogs in the treatment of hematological malignancies. These small molecules act by recruiting ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3a5b6eba7ac746545c7a80669b65a86
https://doi.org/10.1158/1538-7445.am2023-3424
https://doi.org/10.1158/1538-7445.am2023-3424
UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability
Autor:
Jonathan M Tsai, Jacob D Aguirre, Jared Brown, Vivian Focht, Yen-Der Li, Georg Kempf, Lukas Kater, Pius Galli, Simone Cavadini, Brittany E Sandoval, Charles Zou, Justine Rutter, Katherine Donovan, Quinlan Sievers, Paul Park, Jevon A. Cutler, Charlie Hatton, Elizabeth Ener, Micah T Sperling, Mikolaj Slabicki, Peter G. Miller, Roger Belizaire, Adam S. Sperling, Scott A. Armstrong, Eric S. Fischer, Nicolas Thomä, Benjamin L. Ebert
Publikováno v:
Blood. 140:2968-2969
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0fc35d7e1f23e53397d7dc75e887e2c
https://doi.org/10.1182/blood-2022-167615
https://doi.org/10.1182/blood-2022-167615
Autor:
Dennis Gillingham, Jessica A. Gasser, Rob S. Sellar, Eric S. Fischer, Max Jan, Todd R. Golub, Manisha Manojkumar, Nicolas H. Thomä, Quinlan L. Sievers, Claudia Scholl, Stefan Fröhling, Li R. Wang, Zuzanna Kozicka, Katherine A. Donovan, Emma C. Fink, Adam S. Sperling, Yen-Der Li, Steven M. Corsello, Mikolaj Slabicki, Richard D. Bunker, Georg Petzold, Benjamin L. Ebert, Dakota Suchyta, Jonas Koeppel
Publikováno v:
Nature
Molecular glue compounds induce protein–protein interactions that, in the context of a ubiquitin ligase, lead to protein degradation. Unlike traditional enzyme inhibitors, these molecular glue degraders act substoichiometrically to catalyse the rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f945e27008c0da8a9d7dd121f5cde3
https://doi.org/10.1038/s41586-020-2374-x
https://doi.org/10.1038/s41586-020-2374-x
Autor:
Jonathan M. Tsai, Neal I. Lindeman, Athena K. Petrides, Stacy E.F. Melanson, Nicole V. Tolan, Manfred Brigl, Milenko J. Tanasijevic, Yen-Der Li, Sanjat Kanjilal, Sankha S. Basu
Publikováno v:
The Journal of Applied Laboratory Medicine
The COVID-19 pandemic has made a devastating impact on global health and continues to challenge healthcare infrastructure and delivery. The clinical laboratories were no exception as they are responsible for diagnostic testing that dictates many clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146ca37675d512d9145ec1b5d047df28
https://pubmed.ncbi.nlm.nih.gov/33822967
https://pubmed.ncbi.nlm.nih.gov/33822967
Autor:
Mingxing Teng, Wenchao Lu, Donovan, Katherine A., Jialin Sun, Krupnick, Noah M., Nowak, Radosław P., Yen-Der Li, Sperling, Adam S., Tinghu Zhang, Ebert, Benjamin L., Fischer, Eric S., Gray, Nathanael S.
Publikováno v:
Journal of Medicinal Chemistry; 1/13/2022, Vol. 65 Issue 1, p747-756, 10p