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Autor:
Simon J. Charnock, Yuyin Qi, Wolf-Dieter Fessner, Gary W. Black, Anna Szekrenyi, Yen-Chi Thai
Publikováno v:
Bioorganic & Medicinal Chemistry
Enantiomerically pure 1-(6-methoxynaphth-2-yl) and 1-(6-(dimethylamino)naphth-2-yl) carbinols are fluorogenic substrates for aldo/keto reductase (KRED) enzymes, which allow the highly sensitive and reliable determination of activity and kinetic const