Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Yen Sung Huang"'
Autor:
Heng Lin, Yen-Sung Huang, Jean-Michel Fustin, Masao Doi, Huatao Chen, Hui-Huang Lai, Shu-Hui Lin, Yen-Lurk Lee, Pei-Chih King, Hsien-San Hou, Hao-Wen Chen, Pei-Yun Young, Hsu-Wen Chao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Polyploidy is a common feature in normal hepatocytes, however, the pathophysiological function of hepatic hyperpolyploidy is unclear. Here, the authors show that genotoxic stress induces accumulation of hyperpolyploid hepatocytes around the centrilob
Externí odkaz:
https://doaj.org/article/2a6b0a8610cd4b32b27ac9dde0bc48ce
Autor:
Yen Sung Huang, 黃彥淞
89
Replication-competent, E1b-deleted adenoviruses, which can selectively kill tumor cells lacking functional p53, have shown promise for cancer gene therapy. However, some reports indicate that the cytopathic effect of the virus is not absolute
Replication-competent, E1b-deleted adenoviruses, which can selectively kill tumor cells lacking functional p53, have shown promise for cancer gene therapy. However, some reports indicate that the cytopathic effect of the virus is not absolute
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/00842767566596385508
Autor:
Yen-Sung Huang, Chang-Chieh Wu, Che-Chang Chang, Shiu-Feng Huang, Hong-Yi Kuo, Hsiu-Ming Shih
Publikováno v:
Cellular and Molecular Life Sciences. 79
Upregulation of death-domain-associated protein (Daxx) is strongly associated with diverse cancer types. Among these, the clinicopathological significance and molecular mechanisms of Daxx overexpression in colorectal cancer (CRC) remain unknown. Here
Autor:
Jean-Michel Fustin, Hao Wen Chen, Masao Doi, Hsu Wen Chao, Pei Yun Young, Hsien San Hou, Shu Hui Lin, Huatao Chen, Pei Chih King, Yen Lurk Lee, Yen Sung Huang, Hui Huang Lai, Heng Lin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, pp. 645 . https://doi.org/10.1038/s41467-020-20572-8
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, Lee, Y-L, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, 645 . https://doi.org/10.1038/s41467-020-20572-8
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, pp. 645 . https://doi.org/10.1038/s41467-020-20572-8
Lin, H, Huang, Y-S, Fustin, J-M, Doi, M, Chen, H, Lai, H-H, Lin, S-H, Lee, Y-L, King, P-C, Hou, H-S, Chen, H-W, Young, P-Y & Chao, H-W 2021, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', Nature Communications, vol. 12, no. 1, 645 . https://doi.org/10.1038/s41467-020-20572-8
Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for tumor foci emergence is and how this tra
Autor:
Kuo Cheng Lu, Hsiu Ming Shih, Ann Chen, Yen Sung Huang, Cheng Yi Guo, Huey-Kang Sytwu, Hsu Wen Chao, Hsin-Yi Hsieh, Tai Kuang Chao, Chia-Chao Wu
Publikováno v:
Journal of Cellular Physiology. 236:2023-2035
The downregulation of melatonin receptor 1A (MTNR1A) is associated with a range of pathological conditions, including membranous nephropathy. Knowledge of the mechanism underlying MTNR1A expression has been limited to the transcriptional regulation l
Autor:
Ping-Huang Tsai, Yu-Tien Chang, Chang-Han Lo, Hsiu-Ming Shih, Kuo-Cheng Lu, Cheng-Yi Guo, Yen Sung Huang, Yi-Chou Hou, Chia-Chao Wu, Hsin-Yi Hsieh
Publikováno v:
Biochemical and biophysical research communications. 584
Melatonin is a hormone majorly secreted by the pineal gland and contributes to a various type of physiological functions in mammals. The melatonin production is tightly limited to the AANAT level, yet the most known molecular mechanisms underlying AA
Autor:
Chia-Chao Wu, Yen-Sung Huang, Jin-Shuen Chen, Ching-Feng Huang, Sui-Lung Su, Kuo-Cheng Lu, Yuh-Feng Lin, Pauling Chu, Shih-Hua Lin, Huey-Kang Sytwu
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125726 (2015)
Idiopathic membranous nephropathy (MN) is an autoimmune-mediated glomerulonephritis and a common cause of nephrotic syndrome in adults. There are limited available treatments for MN. We assessed the efficacy of resveratrol (RSV) therapy for treatment
Externí odkaz:
https://doaj.org/article/fb9dd7b3eb7643d2a8359602cefa95c3
Autor:
Hao-Wen Chen, Pei-Chih King, Huatao Chen, Yen-Lurk Lee, Pei-Yun Young, Yen Sung Huang, Hsu Wen Chao, Hui-Huang Lai, Heng Lin, Hsien-San Hou, Shu Hui Lin, Masao Doi, Jean-Michel Fustin
Publikováno v:
Fustin, J-M & Chao, H-W 2020, ' Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver ', bioRxiv . https://doi.org/10.1101/2020.08.23.258699
Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for tumor foci emergence is and how this tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954ccd8e4a6f19dab60dc3b0b9367502
https://doi.org/10.1101/2020.08.23.258699
https://doi.org/10.1101/2020.08.23.258699
Autor:
Chia Ju Lin, Tsai Ling Ho, Yen Sung Huang, Ruei Ting Chang, Hsiu-Ming Shih, Jen Chong Jeng, Ying Mei Lin, Shin Mei Liu, Chun Chen Ho, Chun A. Changou, Che Chang Chang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Smad4, a common-mediator of Smads, plays a central role in forming complexes with receptor-phosphorylated Smads, and then transduces transforming growth factor (TGF)-β signals into the nuclei. Although many cellular factors are involved in TGF-β in
Autor:
Jen Chong Jeng, Tsai Ling Ho, Yen Sung Huang, Ruei Ting Chang, Ying Mei Lin, Chia Ju Lin, Hsiu-Ming Shih, Che Chang Chang, Shin Mei Liu, Chun A. Changou, Chun Chen Ho
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.