Plastiques et AntibioRésistance de Bactéries en Eaux Littorales

Autor: Patricia Licznar, Yen Vo Hoang, Pascaline Dieudé, Fabien Aujoulat, Patrick Monfort, Vanina Pascalini, Chrystelle Montigny, Mylène Toubiana, Agnès Masnou, Stefaniya Hantova, Estelle Jumas-Bilak

Publikováno v: International Symposium of LabEx DRIIHM 2022
International Symposium of LabEx DRIIHM 2022, Jun 2022, Nantes, France., 2022, ⟨10.34972/driihm-040f80⟩

One of the consequences of the richness (high diversity of use and economic activities) of the Mediterranean coastal socio-ecosystem is the intensification of anthropogenic pressures exerted on the environment. As part of them, demographic pressure g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8692daffb84ce24e88cf6a10cf0c40b0
https://hal.science/hal-03716551/document

1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors

Autor: Laurent, Gavara, Federica, Verdirosa, Laurent, Sevaille, Alice, Legru, Giuseppina, Corsica, Lionel, Nauton, Paola, Sandra Mercuri, Filomena, Sannio, Filomena, De Luca, Margot, Hadjadj, Giulia, Cerboni, Yen, Vo Hoang, Patricia, Licznar-Fajardo, Moreno, Galleni, Jean-Denis, Docquier, Jean-François, Hernandez

Publikováno v: Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, 2022, 72, pp.116964. ⟨10.1016/j.bmc.2022.116964⟩

International audience; Metallo-β-lactamases (MBLs) represent an increasingly serious threat to public health because of their increased prevalence worldwide in relevant opportunistic Gram-negative pathogens. MBLs efficiently inactivate widely used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ccc5a7fb5d5ee9e7946fc5eee59ccb
https://hal.science/hal-03767295/file/GavaraL_Manuscript.pdf

Abstract 1229: Novel Arf1-targeting ã-dipeptides counteract triple negative breast cancer by inducing autophagic death

Autor: Yen Vo-Hoang, Yong Teng, Alain Chavanieu, Leilei He

Publikováno v: Cancer Research. 81:1229-1229

ADP-ribosylation factor 1 (Arf1) is a crucial regulator in vesicle-mediated membrane trafficking and involved in the activation of signaling molecules. However, the molecular mechanisms underlying Arf1-dependent cancer development and progression are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdf468f72e215f6bc9e89311ff68a6e0
https://doi.org/10.1158/1538-7445.am2021-1229

Design and Synthesis of Arf1-Targeting γ-Dipeptides as Potential Agents against Head and Neck Squamous Cell Carcinoma

Autor: Yong Teng, Leilei He, Sébastien Estaran, Yen Vo-Hoang, Sergio Paiva

Publikováno v: Cells, Vol 9, Iss 2, p 286 (2020)
Cells
Volume 9
Issue 2

Background: Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer-related deaths and calls for new druggable targets. We have previously highlighted the critical role of ADP-ribosylation factor-1 (Arf1) activation in HN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93939ff4eded78cb0391d01958b484c0
https://doi.org/10.3390/cells9020286

Development of the First Oral Bioprecursors of Bis-alkylguanidine Antimalarial Drugs

Autor: Henri Vial, Yen Vo-Hoang, Marjorie Maynadier, Sharon Wein, Mélissa Degardin, Thierry Durand, Jean-Frédéric Duckert, Alexandre Guy, Roger Escale

Publikováno v: ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2014, 9 (2), pp.300-304. ⟨10.1002/cmdc.201300419⟩

International audience; Plasmodium falciparum is responsible of the most severe form of malaria, and new targets and novel chemotherapeutic scaffolds are needed to fight emerging multidrug-resistant strains of this parasite. Bis-alkylguanidines have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432ebd6c4511c50fe4f964494cf79896
https://doi.org/10.1002/cmdc.201300419