Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yeliz Yuva Aydemir"'
Autor:
Gokul Ramaswami, Yeliz Yuva-Aydemir, Brynn Akerberg, Bryan Matthews, Jenna Williams, Gabriel Golczer, Jiaqi Huang, Ali Al Abdullatif, Dann Huh, Linda C. Burkly, Sandra J. Engle, Iris Grossman, Alfica Sehgal, Alla A. Sigova, Robert T. Fremeau, Yuting Liu, David Bumcrot
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Microglia are the resident immune cells in the brain that play a key role in driving neuroinflammation, a hallmark of neurodegenerative disorders. Inducible microglia-like cells have been developed as an in vitro platform for molecular and t
Externí odkaz:
https://doaj.org/article/4c4615fe09d94a8f8fde0749950ac0b4
Autor:
Gokul Ramaswami, Yeliz Yuva-Aydemir, Brynn Akerberg, Bryan Matthews, Jenna Williams, Gabriel Golczer, Jiaqi Huang, Ali Al Abdullatif, Dann Huh, Linda C. Burkly, Sandra J. Engle, Iris Grossman, Alfica Sehgal, Alla A. Sigova, Robert T. Fremeau, Yuting Liu, David Bumcrot
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/bc57d863a5f34f39b8a0f32bb4481c75
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Mechanisms of transcription of expanded G4C2 repeats in C9ORF72, associated with ALS/FTD, are not fully understood. Here authors use both Drosophila and C9ORF72 iPSC-derived neurons and identify AFF2/FMR2 as a regulator of poly(GR) toxicity by regula
Externí odkaz:
https://doaj.org/article/785bcaac78ea4e30bb76e6c0c40d7221
Autor:
Gokul Ramaswami, Yeliz Yuva-Aydemir, Brynn Akerberg, Bryan Matthews, Jenna Williams, Gabriel Golczer, Jiaqi Huang, Dann Huh, Linda C. Burkly, Sandra J. Engle, Alfica Sehgal, Alla A. Sigova, Robert T. Fremeau, Yuting Liu, David Bumcrot
BackgroundMicroglia are the resident immune cells in the brain that play a key role in driving neuroinflammation, a hallmark of neurodegenerative disorders. Inducible microglia-like cells have been developed as an in vitro platform for molecular and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33af0e882b24283dde8e97ae6bd51f69
https://doi.org/10.1101/2023.03.09.531934
https://doi.org/10.1101/2023.03.09.531934
Autor:
Yeliz Yuva Aydemir, Ali Al Abdullatif, Gokul Ramaswami, Gabriel Golczer, Brynn Akerberg, Jenna Weinstein, Yuichi Nishi, Rutuja Pai, Evan Cohick, Bryan Matthews, Yuting Liu, Nikolaos Giagtzoglou, David Bumcrot, Alfica Sehgal
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d65268471275303c511b3cea65449c8e
https://doi.org/10.1002/alz.067563
https://doi.org/10.1002/alz.067563
Autor:
Yeliz Yuva-Aydemir, Xia-Lian Xu, Ozkan Aydemir, Eduardo Gascon, Serkan Sayin, Wenke Zhou, Yang Hong, Fen-Biao Gao
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005264 (2015)
Intragenic microRNAs (miRNAs), located mostly in the introns of protein-coding genes, are often co-expressed with their host mRNAs. However, their functional interaction in development is largely unknown. Here we show that in Drosophila, miR-92a and
Externí odkaz:
https://doaj.org/article/e9ec18847de64f82b8e79d61b1a28402
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Expanded GGGGCC (G4C2) repeats in C9ORF72 cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). How RNAs containing expanded G4C2 repeats are transcribed in human neurons is largely unknown. Here we describe a Drosophila model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710f307695b5ce7ad5b7e60ef3c4eb4f
https://doaj.org/article/785bcaac78ea4e30bb76e6c0c40d7221
https://doaj.org/article/785bcaac78ea4e30bb76e6c0c40d7221
Publikováno v:
Trends in Neurosciences. 41:457-469
GGGGCC (G(4)C(2)) repeat expansion in C9ORF72 is the most common genetic cause of ALS and FTD. An important issue is how repeat RNAs and their translation products—various dipeptide repeat (DPR) proteins—cause neurodegeneration. Drosophila has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f212b05f8cb689566555f61a3dffbbe
https://doi.org/10.1016/j.tins.2018.04.002
https://doi.org/10.1016/j.tins.2018.04.002
Publikováno v:
Development (Cambridge, England). 144(24)
The development of the nervous system requires tight control of cell division, fate specification and migration. The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that affects different steps of cell cycle progression, as wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::096765a658447b8f46da07984c9beb9c
https://pubmed.ncbi.nlm.nih.gov/29084807
https://pubmed.ncbi.nlm.nih.gov/29084807
Publikováno v:
Development.
The development of the nervous system requires tight control of cell division, fate specification and migration. The anaphase promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that affects different steps of cell cycle progression, as wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::159f3cb11ea5f0c47c320998533a301b
https://doi.org/10.1242/dev.152694
https://doi.org/10.1242/dev.152694