Sensitivity of Leishmania spp. to Glibenclamide and 4-Aminopiridine: A Tool for the Study of Drug Resistance Development

Autor: Alicia Ponte-Sucre, Yelitza Campos, Jorge Vázquez, Heidrun Moll, Alexis Mendoza-León

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 92, Iss 5, p 601 (1997)

We have demonstrated that Leishmania spp. grown as promastigotes, are sensitive to the K+ channel inhibitors 4-aminopyridine and glibenclamide. Their host cells, the macrophages, are not affected by similar concentrations of the drugs. We have also i

Externí odkaz: https://doaj.org/article/cf141c9796604989a63ec4b78d61d467

Serological diagnosis of Chagas disease: evaluation and characterisation of a low cost antigen with high sensitivity and specificity

Autor: Katherine Figarella, José Luis Pérez, Walter Mosca, Kate Reina, Luis Briceño, Yelitza Campos

Publikováno v: Memórias do Instituto Oswaldo Cruz, Volume: 104, Issue: 6, Pages: 914-917, Published: SEP 2009
Memórias do Instituto Oswaldo Cruz., Vol 104, Iss 6, Pp 914-917 (2009)

In spite of evident progress in the serology of Chagas disease, the requirement for new diagnostic antigens persists. We have evaluated different antigens obtained from Trypanosoma cruzi grown in medium rich in nutrients or under nutrient stress, aut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d5fde9cee273c7f244ddc7b78f973c
https://doi.org/10.1590/s0074-02762009000600016

Sensitivity of Leishmania spp. to Glibenclamide and 4-Aminopiridine: A Tool for the Study of Drug Resistance Development

Autor: Jorge Vázquez, Heidrun Moll, Yelitza Campos, Alicia Ponte-Sucre, Alexis Mendoza-León

Publikováno v: Memórias do Instituto Oswaldo Cruz., Vol 92, Iss 5, Pp 601-606 (1997)
Memórias do Instituto Oswaldo Cruz., Vol 92, Iss 5, p 601 (1997)
Europe PubMed Central

We have demonstrated that Leishmania spp. grown as promastigotes, are sensitive to the K+ channel inhibitors 4-aminopyridine and glibenclamide. Their host cells, the macrophages, are not affected by similar concentrations of the drugs. We have also i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03a197fc7c6935ed9b2c26d97cabc5b
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761997000500007

Proliferation and bystander suppression induced by antigens of Trypanosoma cruzi. Evaluation with a modification of the T cell blot technique

Autor: Walter, Mosca, Niurka, Navarro, Yelitza, Campos, Luis, Briceño

Publikováno v: Investigacion clinica. 47(3)

We have studied in vitro proliferation induced by soluble antigenic fractions of T. cruzi epimastigotes and trypomastigotes, as well as their regulatory effect on the proliferative response to PPD. Both crude extracts of the parasite as well as bands

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45ebfb0cba6f30758d9122a108ce4b0a
https://pubmed.ncbi.nlm.nih.gov/17672286