Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yelena Z. Ginzburg"'
Autor:
Maria Feola, Andrea Zamperone, Daniel Moskop, Huiyong Chen, Carla Casu, Dechen Lama, Julie Di Martino, Mansour Djedaini, Luena Papa, Marc Ruiz Martinez, Tenzin Choesang, Jose Javier Bravo-Cordero, Matthew MacKay, Paul Zumbo, Nathan Brinkman, Charles S. Abrams, Stefano Rivella, Shilpa Hattangadi, Christopher E. Mason, Ronald Hoffman, Peng Ji, Antonia Follenzi, Yelena Z. Ginzburg
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Maria Feola et al., elucidate the compensatory role of pleckstrin-2 in ineffective erythropoiesis in β-thalassemic mice by reducing cofilin-mediated apoptosis and enhancing enucleation by activating RacGTPases. These findings could support future th
Externí odkaz:
https://doaj.org/article/e6bba204b45a41b58086958c1edd4975
Autor:
Carla Casu, Alison Liu, Gianluca De Rosa, Audrey Low, Aae Suzuki, Sayantani Sinha, Yelena Z. Ginzburg, Charles Abrams, Mariam Aghajan, Shuling Guo, Stefano Rivella
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Polycythemia Vera (PV) is a chronic myeloproliferative neoplasm resulting from an acquired driver mutation in the JAK2 gene of hematopoietic stem and progenitor cells resulting in the overproduction of mature erythrocytes and abnormally high hematocr
Externí odkaz:
https://doaj.org/article/9ba25bee8a6941e696e2191e45a8d141
Autor:
Carla Casu, Roberta Chessa, Alison Liu, Ritama Gupta, Hal Drakesmith, Robert Fleming, Yelena Z. Ginzburg, Brian MacDonald, Stefano Rivella
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
Minihepcidins are hepcidin agonists that have been previously shown to reverse iron overload and improve erythropoiesis in mice affected by non-transfusion-dependent thalassemia. Given the extreme anemia that occurred with the previous model of trans
Externí odkaz:
https://doaj.org/article/f8470b5e406f49f59242abd13d3c64d0
Autor:
Etienne Paubelle, Florence Zylbersztejn, Thiago Trovati Maciel, Caroline Carvalho, Annalisa Mupo, Meyling Cheok, Liesbet Lieben, Pierre Sujobert, Justine Decroocq, Akihiko Yokoyama, Vahid Asnafi, Elizabeth Macintyre, Jérôme Tamburini, Valérie Bardet, Sylvie Castaigne, Claude Preudhomme, Hervé Dombret, Geert Carmeliet, Didier Bouscary, Yelena Z. Ginzburg, Hughes de Thé, Marc Benhamou, Renato C. Monteiro, George S. Vassiliou, Olivier Hermine, Ivan C. Moura
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 739-754.e4 (2020)
Summary: Vitamin D (VD) is a known differentiating agent, but the role of VD receptor (VDR) is still incompletely described in acute myeloid leukemia (AML), whose treatment is based mostly on antimitotic chemotherapy. Here, we present an unexpected r
Externí odkaz:
https://doaj.org/article/53df66dd75014af1bb8489c5bd9cd832
Autor:
Huiyong Chen, Tenzin Choesang, Huihui Li, Shuming Sun, Petra Pham, Weili Bao, Maria Feola, Mark Westerman, Guiyuan Li, Antonia Follenzi, Lionel Blanc, Stefano Rivella, Robert E. Fleming, Yelena Z. Ginzburg
Publikováno v:
Haematologica, Vol 101, Iss 3 (2016)
Iron overload results in significant morbidity and mortality in β-thalassemic patients. Insufficient hepcidin is implicated in parenchymal iron overload in β-thalassemia and approaches to increase hepcidin have therapeutic potential. We have previo
Externí odkaz:
https://doaj.org/article/17baf8f3fd334df0aa5848370955ccf7
Autor:
Huihui Li, Yelena Z. Ginzburg
Publikováno v:
Advances in Hematology, Vol 2010 (2010)
Iron metabolism and erythropoiesis are inextricably linked. The majority of iron extracted from circulation daily is used for hemoglobin synthesis. In the last 15 years, major advances have been made in understanding the pathways regulating iron meta
Externí odkaz:
https://doaj.org/article/f2cad5b8b2d44ee2944d7b047ff34436
Autor:
Yuanliang Peng, Long Liang, Haihang Zhang, Hong Liu, Guanxiong Zhang, Shuming Sun, Xianfeng Guo, Yanpeng Wang, Bin Hu, Rui Liu, Yanan Li, Ling Nie, Ji Zhang, Mao Ye, Yelena Z. Ginzburg, Zhong Lin, Biao Yin, Huiyong Chen, Jing Liu
Publikováno v:
British Journal of Haematology. 201:982-994
Autor:
Huihui Li, Jacob S. Kazmi, Sungkyun Lee, Dachuan Zhang, Xin Gao, Maria Maryanovich, Lidiane Torres, Divij Verma, Libusha Kelly, Yelena Z. Ginzburg, Paul S. Frenette, Deepa Manwani
Publikováno v:
Blood.
Sickle cell disease (SCD) is an inherited disorder resulting from a β-globin gene mutation, and SCD patients experience erythrocyte sickling, vaso-occlusive episodes (VOE), and progressive organ damage. Chronic hemolysis, inflammation, and repeated
Autor:
Wenbin An, Maria Feola, Srinivas Aluri, Marc Ruiz-Martinez, Ashwin Shridharan, Maayan Levy, Eitan Fibach, Xiaofan Zhu, Amit Verma, Yelena Z. Ginzburg
Myelodysplastic syndrome (MDS) is a heterogeneous group of bone marrow stem cell disorders characterized by ineffective hematopoiesis and cytopenias, most commonly anemia. Red cell transfusion therapy for anemia in MDS results in iron overload, corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4536c9547e5701df06440f42315146b2
https://doi.org/10.1101/2022.10.05.510967
https://doi.org/10.1101/2022.10.05.510967