Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yelena Pyatski"'
Autor:
Oscar Conroy, Hequn Wang, Guangru Mao, Gabriela Oana Cula, Carol R. Flach, Qihong Zhang, Michael J. Fevola, Yelena Pyatski, Prithwiraj Maitra, Richard Mendelsohn
Publikováno v:
Skin Research and Technology. 25:653-661
BACKGROUND Skin hydration is essential for maintaining stratum corneum (SC) flexibility and facilitating maturation events. Moisturizers contain multiple ingredients to maintain and improve skin hydration although a complete understanding of hydratio
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1862:183335
Terbinafine (Tbf) is a well-established anti-fungal agent used for management of a variety of dermal conditions including ringworm and athlete's foot. Both the biochemical mechanism of Tbf fungicidal action (based on squalene epoxidase inhibition) an
Publikováno v:
International journal of pharmaceutics. 505(1-2)
For effective topical delivery, a drug must cross the stratum corneum (SC) barrier into viable tissue. The use of permeation enhancers is a widespread approach for barrier modification. In the current study, flufenamic acid (FluA), a non-steroidal an
Publikováno v:
Biophysical Journal. 112:454a-455a
Recent technological advances have led to an increase in the use of confocal Raman microscopy to tackle biophysical and pharmacological issues in topical delivery and dermatology. Advantages of the technique include the ability to optically section i
Autor:
Gregory Ciszewski, John W. Ellingboe, Yelena Pyatski, Ariamala Gopalsamy, Tarek S. Mansour, Kaapjoo Park, Girija Krishnamurthy, Anita Y. M. Howe, Murthy Damarla, Janis Upeslacis, Douglas M. Ho, Boris Feld, Bloom Jonathan David, Kitae Lim, John O'Connell, Mark Orlowski, Shabana Insaf
Publikováno v:
Journal of Medicinal Chemistry. 47:6603-6608
A novel series of HCV NS5B RNA-dependent RNA polymerase inhibitors containing a pyrano[3,4-b]indole scaffold is described leading to the discovery of compound 16, a highly potent and selective inhibitor that is active in the replicon system.