Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yelena Guz"'
Publikováno v:
Endocrinology. 153:3076-3088
Glucagon like peptide-1 (GLP-1) and GLP-2 are hormones secreted by intestinal L cells that stimulate glucose-dependent insulin secretion and regulate intestinal growth, respectively. Mice with deletion of the glucagon receptor (Gcgr) have high levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32567e386535a2a8f243eb8e4106787
https://doi.org/10.1210/en.2012-1120
https://doi.org/10.1210/en.2012-1120
Publikováno v:
Endocrinology. 151:520-528
Whereas it is believed that the pancreatic duct contains endocrine precursors, the presence insulin progenitor cells residing in islets remain controversial. We tested whether pancreatic islets of adult mice contain precursor β-cells that initiate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c5a8381a5349a981b5265c6b4df430
https://doi.org/10.1210/en.2009-0992
https://doi.org/10.1210/en.2009-0992
Autor:
L. C. King, Christopher V.E. Wright, Gladys Teitelman, Roland Stein, A. Fernandes, Yelena Guz
Publikováno v:
Endocrinology. 138:1750-1762
The ability of the adult pancreas to generate new insulin (β) cells has been controversial because of difficulties in unequivocally identifying the precursor population. We recently determined that β cells were generated during development from pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::effe656bdcd3f1b167a0c2b04bd7e88d
https://doi.org/10.1210/endo.138.4.5049
https://doi.org/10.1210/endo.138.4.5049
Publikováno v:
Peptides. 48
To determine whether the glucagon-like peptide-1 receptor (GLP-1r) plays a role in the regulation of intestinal functional activity, we analyzed the distribution of the GLP-1r in mouse tissues and tested if tissues expressing the receptor respond to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fcde158a8939813860e0001a4bb01c
https://pubmed.ncbi.nlm.nih.gov/23927844
https://pubmed.ncbi.nlm.nih.gov/23927844
Publikováno v:
Molecular and cellular endocrinology. 311(1-2)
Glucose homeostasis is determined by a balance between insulin and glucagon, produced by beta and alpha cells of the pancreas respectively. The levels of circulating hormones is partly determined by the mass of these two endocrine cell types. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185fc5e0eca98482d81695c37d0fe225
https://pubmed.ncbi.nlm.nih.gov/19647035
https://pubmed.ncbi.nlm.nih.gov/19647035
Autor:
Patricia Vuguin, Yelena Guz, Lingguang Cui, Mamdouh H. Kedees, Maureen J. Charron, Gladys Teitelman, Carlos Vargas, Donald F. Steiner
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 236(4)
Nestin, a marker of neural stem cells, is also expressed by cells located in the epithelium of the pancreatic primordium and by a subpopulation of exocrine cells but not by endocrine cells. These findings raised the possibility that the pancreatic ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f12f92baa5af864675a0fc16e4ccbd7
https://pubmed.ncbi.nlm.nih.gov/17366624
https://pubmed.ncbi.nlm.nih.gov/17366624
Autor:
Maureen J. Charron, Richard W. Gelling, Patricia Vuguin, Yelena Guz, Lingguang Cui, Mamdouh H. Kedees, Gladys Teitelman, Morris Nejathaim
Although glucagon (GLU) plays a pivotal role in glucose homeostasis, its role in the regulation of fetal growth and maturation is poorly understood. These issues were examined in a line of mice with a global deletion of the GLU receptor (Gcgr-/-), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79267d796ec1611a234e2e8773de46c0
https://europepmc.org/articles/PMC4287247/
https://europepmc.org/articles/PMC4287247/
Publikováno v:
Endocrinology. 142(11)
We previously reported that new beta cells differentiated in pancreatic islets of mice in which diabetes was produced by injection of a high dose of the beta cell toxin streptozotocin (SZ), which produces hyperglycemia due to rapid and massive beta c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d801bac1768d099b2fa85e2b77b41789
https://pubmed.ncbi.nlm.nih.gov/11606464
https://pubmed.ncbi.nlm.nih.gov/11606464
Autor:
M. T. Vincent, Gladys Teitelman, Raymond J. Carroll, Yelena Guz, Donald F. Steiner, Robert E. Hammer, S. J. Chan
We have investigated the mitogenic effect of three mutant forms of human insulin on insulin-producing beta cells of the developing pancreas. We examined transgenic embryonic and adult mice expressing (i) human [AspB10]-proinsulin/insulin ([AspB10]Pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85cdc486790b6dab14ccc1e6ba0c4de
https://europepmc.org/articles/PMC41493/
https://europepmc.org/articles/PMC41493/
Autor:
Mamdouh H. Kedees, Yelena Guz, Patricia M. Vuguin, Carlos Vargas, Lingguang Cui, Donald F. Steiner, Maureen J. Charron, Gladys Teitelman
Publikováno v:
Developmental Dynamics; Apr2007, Vol. 236 Issue 4, p1126-1133, 8p