Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yelena Guttman"'
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Can mutations in Cytochrome P450 3A4 (CYP3A4), the major food- and drug-metabolizing enzyme, serve as biomarkers for personalized precise medicine? Classical genetic studies provide only limited data regarding the frequencies of CYP3A4 mutations and
Externí odkaz:
https://doaj.org/article/5d802a1a3f70441fa784195ac7292636
Autor:
Yelena Guttman, Zohar Kerem
Publikováno v:
International journal of molecular sciences. 23(15)
Modifications of the activity of Cytochrome 450 (CYP) enzymes by compounds in food might impair medical treatments. These CYP-mediated food–drug interactions (FDI) play a major role in drug clearance in the intestine and liver. Inter-individual var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf9a63314b05258a4755361cef782b4
https://pubmed.ncbi.nlm.nih.gov/35955630
https://pubmed.ncbi.nlm.nih.gov/35955630
Autor:
Yelena Guttman, Zohar Kerem
Publikováno v:
Journal of agricultural and food chemistry. 70(8)
CYP3A4 is the main human enzyme responsible for phase I metabolism of dietary compounds, prescribed drugs and xenobiotics, steroid hormones, and bile acids. The inhibition of CYP3A4 activity might impair physiological mechanisms, including the endocr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b747c12bbfb4ba554cf30c22514798
https://pubmed.ncbi.nlm.nih.gov/35104412
https://pubmed.ncbi.nlm.nih.gov/35104412
Autor:
Janak Raj Joshi, Iris Yedidia, Maya Kleiman, Nofar Chriker, Zunzheng Wei, Zohar Kerem, Noam Reznik, Nirmal Khadka, Yelena Guttman
Publikováno v:
Horticulture Research
Soft rot disease caused by Pectobacterium spp. is responsible for severe agricultural losses in potato, vegetables, and ornamentals. The genus Zantedeschia includes two botanical groups of tuberous ornamental flowers that are highly susceptible to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697b8af37ddb3252a594fbb757b158d4
http://europepmc.org/articles/PMC7775464
http://europepmc.org/articles/PMC7775464
Autor:
Zohar Kerem, Ken Declerck, Antje R. Weseler, Dragan Milenkovic, Aalt Bast, Christine Morand, Wim Vanden Berghe, Hagen Schroeter, Sylvain Claude, Yelena Guttman
Publikováno v:
Biochemical Pharmacology, 173:113699. Elsevier Science
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2019, ⟨10.1016/j.bcp.2019.113699⟩
Biochemical Pharmacology, 2020, 173, ⟨10.1016/j.bcp.2019.113699⟩
Biochemical Pharmacology, Elsevier, 2020, 173, ⟨10.1016/j.bcp.2019.113699⟩
Biochemical pharmacology
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2019, ⟨10.1016/j.bcp.2019.113699⟩
Biochemical Pharmacology, 2020, 173, ⟨10.1016/j.bcp.2019.113699⟩
Biochemical Pharmacology, Elsevier, 2020, 173, ⟨10.1016/j.bcp.2019.113699⟩
Biochemical pharmacology
Ingestion of (−)-epicatechin flavanols reverses endothelial dysfunction by increasing flow mediated dilation and by reducing vascular inflammation and oxidative stress, monocyte-endothelial cell adhesion and transendothelial monocyte migration in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8b65e04391bb1f549bad4bf6ba8cbf
https://doi.org/10.1016/j.bcp.2019.113699
https://doi.org/10.1016/j.bcp.2019.113699
Publikováno v:
Food and Chemical Toxicology. 137:111135
Furanocoumarins are the main compounds responsible for the food-drug interactions known as the grapefruit effect, which is caused by the inhibition of CYP3A4-mediated drug metabolism. We evaluated the effects of two new, low-furanocoumarin grapefruit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2f9e8d6240fa9e0c28449d4516d35d
https://doi.org/10.1016/j.fct.2020.111135
https://doi.org/10.1016/j.fct.2020.111135