Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yelena Glinka"'
Autor:
Gérald J Prud'homme, Yelena Glinka, Anna Toulina, Olga Ace, Venkateswaran Subramaniam, Serge Jothy
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13831 (2010)
Cancer stem cells (CSCs) have increased resistance to cancer chemotherapy. They can be enriched as drug-surviving CSCs (D-CSCs) by growth with chemotherapeutic drugs, and/or by sorting of cells expressing CSC markers such as aldehyde dehydrogenase-1
Externí odkaz:
https://doaj.org/article/11a920819b6d4f4cb0a97d094b93491e
Publikováno v:
Biochemistry (Moscow). 86:132-145
Klotho protein affects a number of metabolic pathways essential for pathogenesis of cardio-vascular diseases and their prevention. It inhibits lipid peroxidation and inflammation, as well as prevents endothelial injury and calcification of blood vess
Publikováno v:
Biochemical and biophysical research communications. 525(3)
The levels of the anti-aging protein α-Klotho, in its soluble form (s-Klotho), are depressed in the circulation of patients with type 1 diabetes (T1D) or type 2 diabetes (T2D). Gene transfer experiments have suggested a protective role for β-cell s
Autor:
Sze Wah Samuel Chan, Michael Adam Diamond, Neeru Gupta, Yeni H. Yücel, Eileen Girard, Yelena Glinka, Xun Zhou
Publikováno v:
The British Journal of Ophthalmology
BackgroundCorneal transplant failure with neovascularisation is a leading indication for full-thickness grafts in patients. Lymphangiogenesis is implicated in the pathology of graft failure, and here we systematically evaluate failed human corneal tr
Publikováno v:
Biochemical and biophysical research communications. 493(4)
Systemic gamma-aminobutyric acid (GABA) therapy prevents or ameliorates type 1 diabetes (T1D), by suppressing autoimmune responses and stimulating pancreatic beta cells. In beta cells, it increases insulin secretion, prevents apoptosis, and induces r
Publikováno v:
The Neuropilins: Role and Function in Health and Disease ISBN: 9783319488226
The neuropilins (Nrps) interact with a number of growth factors (GFs) and/or their receptors. This includes vascular endothelial growth factor (VEGF), transforming growth factor β1 (TGF-β1), hepatocyte growth factor (HGF), platelet-derived growth f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2e9e8783251ab7d260e6e81e20d779a
https://doi.org/10.1007/978-3-319-48824-0_11
https://doi.org/10.1007/978-3-319-48824-0_11
Autor:
Craig Hasilo, Yelena Glinka, Steven Paraskevas, Gerald J. Prud'homme, Qinghua Wang, Oleksandr Udovyk
Publikováno v:
Biochemical and Biophysical Research Communications. 452:649-654
We have previously shown that GABA protects pancreatic islet cells against apoptosis and exerts anti-inflammatory effects. Notably, GABA inhibited the activation of NF-κB in both islet cells and lymphocytes. NF-κB activation is detrimental to beta
Publikováno v:
Oncotarget
Extracellular miRNAs are increasingly studied as markers for specific diseases. They are released in biological fluids in a remarkably stable form, and may play a role in intercellular communication. They are thought to be protected against degradati
Autor:
Yelena Glinka, Gerald J. Prud'homme
Publikováno v:
Oncotarget
The neuropilins (Nrps) are multifunctional proteins involved in development, immunity and cancer. Neuropilin-1 (Nrp1), or its homologue neuropilin-2 (Nrp2), are coreceptors that enhance responses to several growth factors (GFs) and other mediators. N
Publikováno v:
Biochemical and Biophysical Research Communications. 425:775-780
Cancer stem cells (CSCs) initiate tumors and have a high resistance to conventional cancer therapy. Tranilast is an orally active drug of low toxicity that exerts inhibitory effects on breast CSCs. This appears to depend on its aryl hydrocarbon recep