Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yelena Galperin"'
Publikováno v:
Blood. 110:3391-3397
Butyrate is a prototype of histone deacetylase inhibitors that is believed to reactivate silent genes by inducing epigenetic modifications. Although butyrate was shown to induce fetal hemoglobin (HbF) production in patients with hemoglobin disorders,
Autor:
Rona Singer Weinberg, Julie Asch, Douglas Jolly, Luis Isola, Yelena Galperin, Lisa Mueller, Lily Kiang
Publikováno v:
American Journal of Hematology. 57:16-23
Cord blood (CB) progenitor/stem cells (P/SC) are ideal targets for early gene therapy in individuals prenatally diagnosed with genetic disorders. Most retroviral transduction protocols were developed using adult peripheral blood stem cells (PBSC) and
Autor:
Yelena Galperin, Andromachi Scaradavou, Luis Isola, David A. Berlin, Jon W. Gordon, Rona Singer Weinberg, Vesna Najfeld, P. Rubinstein
Publikováno v:
Blood. 89:1089-1099
The purposes of the research reported here were first to explore a murine model for human placental and umbilical cord blood transplantation and second to evaluate the engraftment ability of ex vivo cultured hematopoietic cells. Murine near-term feta
Autor:
Susan P. Perrine, Stephen A. Liebhaber, Millicent Sutton, Xinjun Ji, George Stamatoyannopoulos, Yelena Galperin, George F. Atweh, Rona Singer Weinberg, Qiliang Li
Publikováno v:
Blood. 105:1807-1809
Fetal hemoglobin (Hb F) levels increase in most patients with sickle cell disease following intermittent butyrate therapy. Although the full effects of butyrate on Hb F levels usually require multiple treatment cycles, in some patients a peak level i
Autor:
Adrianna Vlachos, Yelena Galperin, Rona Singer Weinberg, Steven M. Fruchtman, Angela Scalise, Vesna Najfeld, Jeffrey M. Lipton
Publikováno v:
British Journal of Haematology. 99:61-63
A 4-year-old girl with transfusion-dependent beta(0)-thalassaemia received an HLA-identical bone marrow transplant (BMT) from her beta(0)-thalassaemia trait sister. Prior to BMT, chromosomal analysis revealed the recipient to have 46,XX,9qh+, a polym
Publikováno v:
Blood. 104:4949-4949
Cord blood is being used at an increasing frequency as a source of stem and progenitor cells in human hematopoietic transplantation. However, very little is known about the kinetics of engraftment of cord blood relative to bone marrow derived stem ce