Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yelena Chernyavskaya"'
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Nanopore sequencing technology has revolutionized the field of genome biology with its ability to generate extra-long reads that can resolve regions of the genome that were previously inaccessible to short-read sequencing platform
Externí odkaz:
https://doaj.org/article/551150241f154d6b98c17d01d1c40b9b
Autor:
Shilpa Sampathi, Yelena Chernyavskaya, Meghan G. Haney, L. Henry Moore, Isabel A. Snyder, Anna H. Cox, Brittany L. Fuller, Tamara J. Taylor, Donglin Yan, Tom C. Badgett, Jessica S. Blackburn
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundAcute Lymphoblastic Leukemia (ALL) is the most common pediatric cancer, and patients with relapsed ALL have a poor prognosis. Detection of ALL blasts remaining at the end of treatment, or minimal residual disease (MRD), and spread of ALL in
Externí odkaz:
https://doaj.org/article/88b631c58e034e68bd52d1b457e89b2d
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-13 (2022)
Background Nanopore sequencing technology has revolutionized the field of genome biology with its ability to generate extra-long reads that can resolve regions of the genome that were previously inaccessible to short-read sequencing platforms. Over 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dae81230a7ae4f6081915d881b9e12
https://doaj.org/article/551150241f154d6b98c17d01d1c40b9b
https://doaj.org/article/551150241f154d6b98c17d01d1c40b9b
Autor:
Isabel A. Snyder, Tom C. Badgett, L. Henry Moore, Shilpa Sampathi, Tamara J. Taylor, Anna H. Cox, Meghan G. Haney, Brittany L. Fuller, Yelena Chernyavskaya, Jessica S. Blackburn
Acute Lymphoblastic Leukemia (ALL) patients that are positive for minimal residual disease (MRD) after therapy or have leukemic infiltration into the central nervous system (CNS) are considered high risk and receive intensive chemotherapy regimens. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a80b19f5abf8a467df29754c44ae18d
https://doi.org/10.1101/2021.09.27.462067
https://doi.org/10.1101/2021.09.27.462067
Autor:
Ye Yang, Ronald C. Bruntz, Teresa W.-M. Fan, Levi J. Beverly, Yan Zhang, Chi V. Dang, Pan Deng, Zhen Qi, Parag P. Shah, Angela Mahan, Richard M. Higashi, Andrew N. Lane, Yelena Chernyavskaya, Huan Song
Publikováno v:
J Biol Chem
Nucleotide synthesis is essential to proliferating cells, but the preferred precursors for de novo biosynthesis are not defined in human cancer tissues. We have employed multiplexed stable isotope-resolved metabolomics to track the metabolism of [(13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66beb6ed6ee4c7d9120f49b34345a18
https://doi.org/10.1074/jbc.ra119.008743
https://doi.org/10.1074/jbc.ra119.008743
Autor:
Min Wei, Jessica S. Blackburn, Yelena Chernyavskaya, K. Martin Chow, Zachary A. Williamson, Konstantin V. Korotkov, Caroline N. Smith, Louis B. Hersh
Phosphatase of Regenerating Liver-3 (PRL-3) is associated with cancer progression and metastasis in various solid tumors and leukemias. The mechanisms that drive PRL-3’s oncogenic functions are not well understood, in part due to a lack of research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d01490d4b288ff9ef7fa3237f5ca6dbb
https://doi.org/10.1101/2020.10.02.311787
https://doi.org/10.1101/2020.10.02.311787
Autor:
Meghan G. Haney, Henry Moore, Tom C. Badgett, Jessica S. Blackburn, Shilpa Sampathi, Yelena Chernyavskaya
Publikováno v:
Blood. 136:7-8
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a relapse rate of 15%. The presence of lymphoblasts in the central nervous system (CNS) is a negative prognostic indicator and a frequent site of disease relapse. CNS diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef400852becff51eb421d9e2a3132d4a
https://doi.org/10.1182/blood-2020-143227
https://doi.org/10.1182/blood-2020-143227
Autor:
Meghan G. Haney, Tom C. Badgett, Shilpa Sampathi, Jessica S. Blackburn, Yelena Chernyavskaya, Henry Moore
Publikováno v:
Journal of Clinical Oncology. 39:10034-10034
10034 Background: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with a relatively high relapse rate, which is associated with poor prognosis. Currently, minimal residual disease (MRD) at the end of induction and consolidatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abfb01c7a4356c6f61849bad3f7b0933
https://doi.org/10.1200/jco.2021.39.15_suppl.10034
https://doi.org/10.1200/jco.2021.39.15_suppl.10034
Autor:
Thaddeus D. Allen, Nourdine Bah, Teresa W.-M. Fan, Richard M. Higashi, Andrew N. Lane, Yelena Chernyavskaya, Mariia Yuneva, Michael Bousamra, Katherine Sellers, Wei Lin, James I. MacRae, Jinlian Tan, Andrés Méndez-Lucas
Publikováno v:
British Journal of Cancer
Background Previous studies suggested that the metabolism is differently reprogrammed in the major subtypes of non-small cell lung cancer (NSCLC), squamous cell carcinomas (SCC) and adenocarcinomas (AdC). However, a comprehensive analysis of this dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17eefe117dd8d39ce5fa2a1dfec68df7
https://pubmed.ncbi.nlm.nih.gov/31114016
https://pubmed.ncbi.nlm.nih.gov/31114016
Autor:
Raksha Mudbhary, Kirsten C. Sadler, Jeffrey A. Yoder, Xiaochen Sun, Bhavani P. Madakashira, Vinitha Jacob, Shuang Wang, Elena Magnani, Chi Zhang, Debra A. Tokarz, Yelena Chernyavskaya, Smita Gopinath, Yujin Hoshida
Complex cytoplasmic nucleotide-sensing mechanisms can recognize foreign DNA based on a lack of methylation and initiate an immune response to clear the infection. Zebrafish embryos with global DNA hypomethylation caused by mutations in the ubiquitin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bdae2311819fb1abb05ef51ee8e868
https://europepmc.org/articles/PMC5592811/
https://europepmc.org/articles/PMC5592811/