Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yelena Chepurko"'
Autor:
Asher Shainberg, Yelena Chepurko, Edith Hochhauser, Michael Arad, Eyal E Porat, Jonathan G. Seidman, Michael Eldar, Efrat Kurtzwald-Josefson, Guy Katz, Christine E. Seidman
Publikováno v:
Journal of Applied Physiology. 113:1677-1683
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal ventricular arrhythmia evoked by physical or emotional stress. Recessively inherited CPVT is caused by either missense or null-allele mutations in the cardiac calsequestrin (CAS
Autor:
Edith Hochhauser, Dilip K. Tosh, Alexandra Litinsky, Asher Shainberg, Kenneth A. Jacobson, Bella Chanyshev, Ahuva Isak, Khai Phan, Yelena Chepurko, Zhan-Guo Gao
Publikováno v:
Pharmacological Research. 65:338-346
Adenosine released during myocardial ischemia mediates cardioprotective preconditioning. Multivalent drugs covalently bound to nanocarriers may differ greatly in chemical and biological properties from the corresponding monomeric agents. Here, we con
Autor:
Edith Hochhauser, Oma Avlas, Hemda Schmilovitz-Weiss, Yelena Chepurko, Reut Fallach, Orit Pappo, Ziv Ben-Ari
Publikováno v:
Cellular Physiology and Biochemistry. 30:489-498
Background/Aims: Toll-like receptor 4 (TLR4) is expressed on hepatic non-parenchymal cells and hepatocytes. Hepatic signaling through TLR4 is critical in the pathogenesis of ischemia reperfusion injury (IRI) and leads to the release of cytokines. The
Publikováno v:
Molecular and Cellular Biochemistry. 363:167-178
The hypothesis of the present study is that cardiomyocytes subjected to prolonged ischemia, may release survival factors that will protect new cardiac cells from ischemic stress. We exposed neonatal rat cardiomyocyte primary cultures to hypoxia, coll
Autor:
Orna Avlas, Edith Hochhauser, Reut Fallach, Eyal E Porat, Asher Shainberg, Yelena Chepurko, Michael Fainblut
Publikováno v:
Journal of Molecular and Cellular Cardiology. 48:1236-1244
Toll-like receptors are expressed in immune cells and cardiac muscle. We examined whether the cardiac Toll-like receptor 4 (TLR4) is involved in the acute myocardial dysfunction caused by septic shock and myocardial ischemia (MI). We used wild type m
Autor:
Asher Shainberg, Alex Sagie, Edith Hochhauser, Yelena Chepurko, Eyal E Porat, Avishag K. Emanuelov, Doron Kaplan, Michael Arad
Publikováno v:
Biochemical Pharmacology. 79:180-187
Cardiotoxicity associated with doxorubicin (DOX) treatment limits the therapeutic efficiency of this drug against cancer. 2-Chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide (Cl-IB-MECA), a selective agonist of A(3) adenosine receptor (A(3)R),
Autor:
Lina Kapustin, Georgios P. Georghiou, Ehud Raanani, Marius Berman, Yelena Chepurko, Bernardo A. Vidne, Edith Hochhauser, David Hasdai
Publikováno v:
Interactive CardioVascular and Thoracic Surgery. 4:232-237
BACKGROUND Prior studies have suggested that inflammation and possibly bacterial infections play a role in atherogenesis and in the clinical pathogenesis of cardiovascular diseases. Treatment with the macrolide antibiotics has been associated with im
Autor:
Edith Hochhauser, Jonathan G. Seidman, Bernardo A. Vidne, Michal Ofir, Michael Arad, Christine E. Seidman, Eyal E Porat, Dov Freimark, Yelena Chepurko, Bruce E. Kemp
Publikováno v:
Biochemical pharmacology. 75(7)
During ischemia, endogenous glycogen becomes the principal substrate for energy through glycolysis. Cardiac-specific manipulation of AMP-activated protein kinase (AMPK) by over-expression of its regulatory gamma-subunit induces glycogen storage. The
Autor:
Bernardo A. Vidne, Asher Shainberg, Edith Hochhauser, Yelena Chepurko, Eyal E Porat, Dorit Leshem
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:S196
Autor:
Bernardo A. Vidne, Edith Hochhauser, Eyal E Porat, Yelena Chepurko, Alex Sagie, Smadar Yitzhaki, Asher Shainberg
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:S217