Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yelena Abramyants"'
Autor:
Lucy Ghoda, Megan Gilchrist, Marianne Z. Metz, Simon F. Lacey, Margarita Gutova, Karen S. Aboody, Timothy W. Synold, Philip M. Potter, Yelena Abramyants, Michael E. Barish, Revathiswari Tirughana, Christine E. Brown, Joseph Najbauer, Jana Portnow, Tien Vo
Publikováno v:
Stem Cells Translational Medicine. 2:983-992
CPT-11 (irinotecan) has been investigated as a treatment for malignant brain tumors. However, limitations of CPT-11 therapy include low levels of the drug entering brain tumor sites and systemic toxicities associated with higher doses. Neural stem ce
Autor:
K Mittelholtz, Alexander J. Annala, Rex Moats, Joseph Najbauer, Yelena Abramyants, Seung U. Kim, Kelsey A. Herrmann, Karen S. Aboody, X-H Shi, Michael E. Barish, Melvin Blanchard, Timothy W. Synold, Vazgen Khankaldyyan, Margarita Gutova, Massimo D'Apuzzo, Gregory M. Shackleford
Publikováno v:
Gene therapy
Medulloblastoma is a heterogeneous diffuse neoplasm that can be highly disseminated, and is the most common malignant childhood brain tumor. Although multimodal treatments have improved survival rates for patients with medulloblastoma, these tumors a
Autor:
Michael E. Barish, Rex Moats, Diana Oganesyan, Margarita Gutova, Maciej S. Lesniak, Irina V. Balyasnikova, Frey Ii William H, Yelena Abramyants, Lusine Danielyan, Joseph Najbauer, Karen S. Aboody, Davit Shahmanyan, Vazgen Khankaldyyan
Despite aggressive multimodal therapy and advances in imaging, surgical and radiation techniques, high-grade gliomas remain incurable, with patient survival often measured in months. Treatment failure is largely attributable to the invasive nature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11b7f5236b49df5bef07dfaefb70444
https://europepmc.org/articles/PMC4638452/
https://europepmc.org/articles/PMC4638452/
Autor:
Christine E. Brown, Joseph Najbauer, Seung U. Kim, Alexander J. Annala, Yelena Abramyants, Maciej S. Lesniak, Massimo D'Apuzzo, Lucy Ghoda, Megan Gilchrist, Karen S. Aboody, Kelsey A. Herrmann, Marianne Z. Metz, Vazgen Khankaldyyan, Joseph A. Frank, Michael E. Barish, M. Suzette Blanchard, Margarita Gutova, Rex Moats
Publikováno v:
Stem cells translational medicine. 2(10)
Numerous stem cell-based therapies are currently under clinical investigation, including the use of neural stem cells (NSCs) as delivery vehicles to target therapeutic agents to invasive brain tumors. The ability to monitor the time course, migration