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Akademický článek

LncRNA OIP5-AS1/miR-410-3p/Wnt7b axis promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via regulating the Wnt/β-catenin pathway

Autor: Yuan Sun, Hui Jiang, LingYu Pan, YanQuan Han, Yan Chen, Yeke Jiang, Yongzhong Wang

Publikováno v: Autoimmunity, Vol 56, Iss 1 (2023)

LncRNA OIP5-AS1 has a common gene imbalance in various cancers and tumours, which plays an important role in regulating its biological function. However, there are few studies on lncRNA OIP5-AS1 in rheumatoid arthritis (RA). The purpose of the presen

Externí odkaz: https://doaj.org/article/e38151e231814beaa283997e18d9c2be

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Akademický článek

Investigating the mechanism of action of Yanghe Pingchuan Granule in the treatment of bronchial asthma based on bioinformatics and experimental validation

Autor: Chunxia Gong, Lingyu Pan, Yeke Jiang, Yehong Sun, Yanquan Han, Dianlei Wang, Yongzhong Wang

Publikováno v: Heliyon, Vol 9, Iss 11, Pp e21936- (2023)

Background: Yanghe Pingchuan Granule (YPG) is a patented Chinese medicine developed independently by the Anhui Provincial Hospital of Traditional Chinese Medicine. For many years, it has been used for the treatment of asthma with remarkable clinical

Externí odkaz: https://doaj.org/article/936a1609baad40bd888f1b5ea9380cd1

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Akademický článek

Induction mechanism of ferroptosis: A novel therapeutic target in lung disease

Autor: Lingyu Pan, Chunxia Gong, Yehong Sun, Yeke Jiang, Xianchun Duan, Yanquan Han, Yongzhong Wang

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Ferroptosis is a newly discovered form of non-apoptotic regulatory cell death driven by iron-dependent lipid peroxidation. Ferroptosis significantly differs from other forms of cell death in terms of biochemistry, genetics, and morphology. Ferroptosi

Externí odkaz: https://doaj.org/article/f3a78b5d59f44a8380f5f75efcbabd30

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Akademický článek

Yanghe Pingchuan Granules Alleviate Airway Inflammation in Bronchial Asthma and Inhibit Pyroptosis by Blocking the TLR4/NF-κB/NRLP3 Signaling Pathway

Autor: Lingyu Pan, Yan Chen, Yeke Jiang, Yehong Sun, Yanquan Han, Yongzhong Wang

Publikováno v: Mediators of Inflammation, Vol 2022 (2022)

Bronchial asthma (BA) is a chronic inflammatory disease of the airway. Previous research has shown that Yanghe Pingchuan granules (YPGs) exert a precise therapeutic effect on BA. In our previous work, we showed that YPGs improved inflammation of the

Externí odkaz: https://doaj.org/article/158c072f8ebb49ed9bffe29d657ba302

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Total Saponins of Radix Clematis Regulate Fibroblast-Like Synoviocyte Proliferation in Rheumatoid Arthritis via the LncRNA OIP5-AS1/MiR-410-3p/Wnt7b Signaling Pathway

Autor: Lingyu Pan, Yuan Sun, Hui Jiang, Yan Chen, Yeke Jiang, Yanquan Han, Yongzhong Wang

Publikováno v: Evidence-Based Complementary and Alternative Medicine. 2022:1-12

Background. Rheumatoid arthritis (RA) is the most common autoimmune disease and affects multiple joints. Previous studies have shown that total saponins of Radix clematidis (TSC) have a clear therapeutic effect on RA, but the specific mechanism has n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8948fc2b3d03b9e776e5ab461365ce9d
https://doi.org/10.1155/2022/8393949

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