The genome organization of Thermotoga maritima reflects its lifestyle.

Autor: Haythem Latif, Joshua A Lerman, Vasiliy A Portnoy, Yekaterina Tarasova, Harish Nagarajan, Alexandra C Schrimpe-Rutledge, Richard D Smith, Joshua N Adkins, Dae-Hee Lee, Yu Qiu, Karsten Zengler

Publikováno v: PLoS Genetics, Vol 9, Iss 4, p e1003485 (2013)

The generation of genome-scale data is becoming more routine, yet the subsequent analysis of omics data remains a significant challenge. Here, an approach that integrates multiple omics datasets with bioinformatics tools was developed that produces a

Externí odkaz: https://doaj.org/article/e24e7e0d1dda454ea4079c80962aad27

The Validation of the Sample6 DETECTTM HT/L for AOAC Research Institute

Autor: Patrick Bird, Lauren Malsick, Yekaterina Tarasova, Nicole Klass, Elijah Carrier, M Joseph Benzinger, David Goins, Chuxuan Hu, Sophie Daudenarde, Daniel Robert Brownell, James Agin, Brittney Peirson, Kakolie Banerjee, Michael Sandor Koeris

Publikováno v: Journal of AOAC INTERNATIONAL. 101:1584-1592

Background: Listeria spp. are an important foodborne human pathogen because of their ability to cause disease and high mortality in individuals, particularly pregnant women, neonates, the elderly, immunocompromised individuals, and children. The Samp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ecf73bcf3d4262929f7f9d4a5cc7b398
https://doi.org/10.5740/jaoacint.17-0484

Rational design of thiolase substrate specificity for metabolic engineering applications

Autor: Yekaterina Tarasova, Kristala L. J. Prather, Bruce Tidor, Brian M. Bonk, Michael A. Hicks

Publikováno v: Prof. Prather

© 2018 Wiley Periodicals, Inc. Metabolic engineering efforts require enzymes that are both highly active and specific toward the synthesis of a desired output product to be commercially feasible. The 3-hydroxyacid (3HA) pathway, also known as the re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5e80614599354e8775044e95020f25
https://hdl.handle.net/1721.1/134936

Engineering E. coli for the biosynthesis of 3-hydroxy-γ-butyrolactone (3HBL) and 3,4-dihydroxybutyric acid (3,4-DHBA) as value-added chemicals from glucose as a sole carbon source

Autor: Yekaterina Tarasova, Collin H. Martin, Himanshu Hemant Dhamankar, Kristala L. J. Prather

Publikováno v: Prof. Prather via Erja Kajosalo

3-hydroxy-γ-butyrolactone (3HBL) is a versatile chiral synthon, deemed a top value-added chemical from biomass by the DOE. We recently reported the first biosynthetic pathway towards 3HBL and its hydrolyzed form, 3,4-dihydroxybutyric acid (3,4-DHBA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9a34582ba3c7594f0bdea1acaf8b31
https://doi.org/10.1016/j.ymben.2014.06.004

Transcriptional regulation of the carbohydrate utilization network in Thermotoga maritima

Autor: Yekaterina Tarasova, Dmitry A. Rodionov, Dmitry A. Ravcheev, Xiaoqing Li, Andrei L. Osterman, Karsten Zengler, Irina A. Rodionova, Vasiliy A. Portnoy

Publikováno v: Frontiers in Microbiology, Vol 4 (2013)
Frontiers in Microbiology, 4(244), 1-14. Lausanne, Switzerland: Frontiers Research Foundation (2013).
Frontiers in Microbiology

Hyperthermophilic bacteria from the Thermotogales lineage can produce hydrogen by fermenting a wide range of carbohydrates. Previous experimental studies identified a large fraction of genes committed to carbohydrate degradation and utilization in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab03ef881899c9fdf1bc4e7ff5f0b8d8
http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00244/full