Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Yekaterina A Miroshnikova"'
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Fig. S2. Interstitial fluid pressure (IFP) pressure sensors do not increase reactive gliosis or microglia activation during tumor progression. (A, B) GFAP+ reactive astrocytes (DAB; brown) and (C, D) Iba1+ tumor-associated macrophages (DAB; brown) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469f715d35ef062041e132ffa4999561
https://doi.org/10.1158/1541-7786.22513050.v1
https://doi.org/10.1158/1541-7786.22513050.v1
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Fig. S4. AF treatment results in no changes in body weight for mice xenografted with GBM43 cells and resulted in complete tumor regression in an EGFRvIII-expressing GBM allograft model. (A, B) SPC or Salovum treatment had no effect on body weight in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14e26ea7e488c1186e14a57e20e8f1b
https://doi.org/10.1158/1541-7786.22513041
https://doi.org/10.1158/1541-7786.22513041
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Interstitial fluid pressure (IFP) presents a barrier to drug uptake in solid tumors, including the aggressive primary brain tumor glioblastoma (GBM). It remains unclear how fluid dynamics impacts tumor progression and can be targeted therapeutically.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0abd1a8d41cfcedb773f67cfcb00588
https://doi.org/10.1158/1541-7786.c.6540420.v1
https://doi.org/10.1158/1541-7786.c.6540420.v1
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Fig. S3. AF treatment increases drug uptake resulting in increased survival of GBM43 xenografted mice. (A, B) SPC diet increased uptake and reduced clearance of tail-vein injected gadolinium in mice xenografted with GBM43 cells. (C) Treatment regimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7197aeb0aee8f0a62000383bc16889a9
https://doi.org/10.1158/1541-7786.22513047.v1
https://doi.org/10.1158/1541-7786.22513047.v1
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Compression-induced changes in the transcriptional GBM phenotype. Differentially expressed genes in tumorspheres derived from human GBMs (GBM5, GBM14, GBM34, and GBM43) when comparing compression to other conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1789986a60b5f0ae643d577602928d1c
https://doi.org/10.1158/1541-7786.22513029.v1
https://doi.org/10.1158/1541-7786.22513029.v1
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Fig. S5. AF prevents restoration of cell volume of GC22 cells under hyperosmolar conditions. (A) AF peptide (5 μg/ml) and bumetanide (BMT, 10 μM) reduced fluorescence of excited calcein-AM dye when GC22 cells were transferred to hypertonic conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e900ab047776fabc9af108ae3dd3b58
https://doi.org/10.1158/1541-7786.22513038.v1
https://doi.org/10.1158/1541-7786.22513038.v1
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Fig. S7. AF reversed compression-induced transcriptional phenotype of GBM tumorspheres. Both (A-B) smaller and (C-D) larger GBM43 tumorspheres expanded in response to 48h compression. (***P < 0.05, Student's t-test). (E) Principle components analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726858f09f5736dbf9e03611672de5cf
https://doi.org/10.1158/1541-7786.22513032
https://doi.org/10.1158/1541-7786.22513032
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Dandan Sun, Daniele Arosio, Joanna J. Phillips, Mitchel S. Berger, Sergey Magnitsky, Jason A. Burdick, Janna K. Mouw, Olle R. Lindberg, Supna Saxena, Jacqueline R. Trzeciak, Edith Yuan, Trenten Fenster, David A. Quigley, Christin Schmidt, Jon N. Lakins, Aurora Idilli, Wen Zhu, Aaron Frantz, Yekaterina A. Miroshnikova, Hanna Sabelström, Shirin Ilkhanizadeh
Fig. S1. AF treatment increases ADC in tumor tissues. MR imaging showing an increase of (A) ADC in xenografted mice treated with nasal AF or SPC-diet with corresponding (B) T2w images.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afff7ce23cffc049ae828ccbb412a89b
https://doi.org/10.1158/1541-7786.22513053
https://doi.org/10.1158/1541-7786.22513053
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Christin Schmidt, Robyn A. Wong, Nicolas A. Salvatierra, Yekaterina A. Miroshnikova, Susan Wang, Shirin Ilkhanizadeh, Jasmine Lau
Figure S3: IR induces a sustained cell-intrinsic mesenchymal transition in HGG cell cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0aa8d5da993147333132cf24b5ffbd
https://doi.org/10.1158/0008-5472.22405167.v1
https://doi.org/10.1158/0008-5472.22405167.v1
Autor:
Anders I. Persson, William A. Weiss, Valerie M. Weaver, Christin Schmidt, Robyn A. Wong, Nicolas A. Salvatierra, Yekaterina A. Miroshnikova, Susan Wang, Shirin Ilkhanizadeh, Jasmine Lau
Figure S5: JAK1/2 inhibitors block a transient STAT3 activation following IR in cultured murine proneural HGG cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e2ec6adae3a16aa646c273f46bf0af
https://doi.org/10.1158/0008-5472.22405158.v1
https://doi.org/10.1158/0008-5472.22405158.v1