Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yejing Jeong"'
Autor:
Jinuk Kim, Wonhee Han, Taeyong Park, Eun Jin Kim, Injin Bang, Hyun Sik Lee, Yejing Jeong, Kyeonghwan Roh, Jeesoo Kim, Jong-Seo Kim, Chanhee Kang, Chaok Seok, Jin-Kwan Han, Hee-Jung Choi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The low-density lipoprotein receptor-related protein 6 (LRP6) is a co-receptor of the β-catenin-dependent Wnt signaling pathway and interacts with the Wnt inhibitor sclerostin (SOST). Here the authors present the crystal structure of SOST in complex
Externí odkaz:
https://doaj.org/article/ce4b2712b2dc4868b8f366fb0464dc32
Publikováno v:
Biomolecules & Therapeutics
Sclerostin (SOST), a regulator of bone formation in osteocytes, inhibits the canonical Wnt signaling by interacting with low-density lipoprotein receptor-related protein 5/6 (LRP5/6) to prevent Wnt binding. Loss-of-function mutations of the SOST gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382826535faf8bcf08026d5eed15da26
http://europepmc.org/articles/PMC8411024
http://europepmc.org/articles/PMC8411024