Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Yejin Yun"'
Autor:
Hwalin Yi, Yejin Yun, Won Hoon Choi, Hye-Yeon Hwang, Ju Hyuen Cha, Heeyoung Seok, Jae-Jin Song, Jun Ho Lee, Sang-Yeon Lee, Daesik Kim
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102199- (2024)
Pathogenic structure variations (SVs) are associated with various types of cancer and rare genetic diseases. Recent studies have used Cas9 nuclease with paired guide RNAs (gRNAs) to generate targeted chromosomal rearrangements, focusing on producing
Externí odkaz:
https://doaj.org/article/8c333f9f30f44066829147680fbc0ce9
Autor:
Sung Ho Cho, Yejin Yun, Dae Hee Lee, Joo Hyun Cha, So Min Lee, Jehyun Lee, Myung Hwan Suh, Jun Ho Lee, Seung-Ha Oh, Moo Kyun Park, Sang-Yeon Lee
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background TMC1, which encodes transmembrane channel-like protein 1, forms the mechanoelectrical transduction (MET) channel in auditory hair cells, necessary for auditory function. TMC1 variants are known to cause autosomal dominant (DFNA36)
Externí odkaz:
https://doaj.org/article/ffbdb719dd054815898e37924ce7cf86
Autor:
Sang-Yeon Lee, Min Young Kim, Jin Hee Han, Sang Soo Park, Yejin Yun, Seung-Cheol Jee, Jae Joon Han, Jun Ho Lee, Heeyoung Seok, Byung Yoon Choi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract POU4F3, a member of the POU family of transcription factors, commonly causes autosomal dominant deafness. Exome sequencing was used to identify four novel variants in POU4F3 (NM_002700.2), including c.564dupA: p.Ala189SerfsTer26, c.743T > C:
Externí odkaz:
https://doaj.org/article/9c67b1fd58ab4b5b843076a19b199600
Autor:
Somin Lee, Yejin Yun, Ju Hyuen Cha, Jin Hee Han, Dae Hee Lee, Jae-Jin Song, Moo Kyun Park, Jun Ho Lee, Seung Ha Oh, Byung Yoon Choi, Sang-Yeon Lee
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Branchio-oto-renal (BOR)/branchio-otic (BO) syndrome is a rare disorder and exhibits clinically heterogenous phenotypes, marked by abnormalities in the ear, branchial arch, and renal system. Sporadic cases of atypical BOR/BO syndrome have be
Externí odkaz:
https://doaj.org/article/7877d998df4b40d28ae47aec50d32678
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17077 (2023)
The ClC-K channels CLCNKA and CLCNKB are crucial for the transepithelial transport processes required for sufficient urinary concentrations and sensory mechanoelectrical transduction in the cochlea. Loss-of-function alleles in these channels are asso
Externí odkaz:
https://doaj.org/article/fdb62fbcc9c94f5f8d748d7397c5562a
Publikováno v:
Physiological Reports, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Shift work disorders have become an emerging concern worldwide. Shift disorders encompass a wide range of illnesses that have yet to be identified. The study focused on the relationship between shift work disorders and insulin resistance. Pr
Externí odkaz:
https://doaj.org/article/848f65dfd1cd4d6399234de0aa853dd6
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract While chronic restraint stress (CRS) results in depression-like behaviors possibly through oxidative stress in the brain, its molecular etiology and the development of therapeutic strategies remain elusive. Since oxidized proteins can be tar
Externí odkaz:
https://doaj.org/article/2497ca1e287e4a02b53bfc53487afee6
Autor:
Eunkyoung Kim, Seoyoung Park, Jung Hoon Lee, Ji Young Mun, Won Hoon Choi, Yejin Yun, Jeeyoung Lee, Ji Hyeon Kim, Min-Ji Kang, Min Jae Lee
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 732-743 (2018)
Summary: The ubiquitin-proteasome system and the autophagy-lysosome system are two major intracellular proteolytic pathways in eukaryotes. Although several biochemical mechanisms underlying the crosstalk between them have been suggested, little is kn
Externí odkaz:
https://doaj.org/article/8d65e02e1e744c458528dbd6b34b2102
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 1, Pp 67-82 (2018)
Background/Aims: The 26S proteasome is the key proteolytic complex for recognition and degradation of polyubiquitinated target substrates in eukaryotes. Among numerous proteasome-associated proteins, a deubiquitinating enzyme (DUB) USP14 has been ide
Externí odkaz:
https://doaj.org/article/246ba8e6c8d9444cba4e854e2993d0ef
Autor:
Yejin Yun1, Sang-Yeon Lee1,2,3 maru4843@hanmail.net
Publikováno v:
Journal of Audiology & Otology. Apr2024, Vol. 28 Issue 2, p88-92. 5p.