Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Yejia Zhang"'
Autor:
Zuozhen Tian, Frances S. Shofer, Mingyue Fan, Alec Z. Sandroni, Lutian Yao, Lin Han, Ling Qin, Motomi Enomoto-Iwamoto, Yejia Zhang
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101059- (2024)
Externí odkaz:
https://doaj.org/article/8e54348c408f41e080b362813cc2c8dc
Autor:
Ke Lu, Qingyun Wang, Hua Jiang, Jun Li, Zhou Yao, Yongcan Huang, Jianquan Chen, Yejia Zhang, Guozhi Xiao, Xueyu Hu, Zhuojing Luo, Liu Yang, Liping Tong, Di Chen
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Spine degeneration is an aging-related disease, but its molecular mechanisms remain unknown, although elevated β-catenin signaling has been reported to be involved in intervertebral disc degeneration. Here, we determined the role of β-cate
Externí odkaz:
https://doaj.org/article/1aeee8debffd4c44a91a31f8c70b7b0d
Autor:
Naixin Song, Pengfei Xie, Wen Shen, Hanju Oh, Yejia Zhang, Flavia Vitale, Mehdi Javanmard, Mark G. Allen
Publikováno v:
Microsystems & Nanoengineering, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Impedance-based protein detection sensors for point-of-care diagnostics require quantitative specificity, as well as rapid or real-time operation. Furthermore, microfabrication of these sensors can lead to the formation of factors suitable f
Externí odkaz:
https://doaj.org/article/e77907fa947f4086aba9e1301378c41a
Publikováno v:
Genes and Diseases, Vol 8, Iss 1, Pp 38-47 (2021)
In the past 20 years, patients with rheumatoid arthritis (RA), Crohn's disease (CD), and other immune diseases have witnessed the impact of a great treatment advance with the availability of biological TNFα inhibitors. With 5 approved anti-TNFα bio
Externí odkaz:
https://doaj.org/article/7c2f336b5c0c47b3b5389a7f5fc72807
Autor:
Yejia Zhang, Zuozhen Tian, David Gerard, Lutian Yao, Frances S. Shofer, Gabriella Cs-Szabo, Ling Qin, Maurizio Pacifici, Motomi Enomoto-Iwamoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We found ADAM8 enzymatic activity elevated in degenerative human intervertebral disc (IVD). Here, we examined the discs in ADAM8-inactivation mice that carry a mutation preventing self-activation of the enzyme. Surprisingly, elevated gene ex
Externí odkaz:
https://doaj.org/article/29482a7dd36f42fc82304c841792897b
Autor:
Yejia Zhang, Tian Xu, Huizhen Tian, Jianfeng Wu, Xiaomin Yu, Lingbing Zeng, Fadi Liu, Qiong Liu, Xiaotian Huang
Publikováno v:
Cancers, Vol 14, Iss 24, p 6206 (2022)
Colon cancer is the second leading cause of cancer-related death, and there are few effective therapies for colon cancer. This study explored the use of coxsackievirus group B3 (CVB3) as an oncolytic virus for the treatment of colon cancer. In this s
Externí odkaz:
https://doaj.org/article/468d2cbf0e0147eca780f5fbfc64e43b
Autor:
Itzel Paola Melgoza, Srish S. Chenna, Steven Tessier, Yejia Zhang, Simon Y. Tang, Takashi Ohnishi, Emanuel José Novais, Geoffrey J. Kerr, Sarthak Mohanty, Vivian Tam, Wilson C. W. Chan, Chao‐Ming Zhou, Ying Zhang, Victor Y. Leung, Angela K. Brice, Cheryle A. Séguin, Danny Chan, Nam Vo, Makarand V. Risbud, Chitra L. Dahia
Publikováno v:
JOR Spine, Vol 4, Iss 2, Pp n/a-n/a (2021)
Abstract Mice have been increasingly used as preclinical model to elucidate mechanisms and test therapeutics for treating intervertebral disc degeneration (IDD). Several intervertebral disc (IVD) histological scoring systems have been proposed, but n
Externí odkaz:
https://doaj.org/article/6b4b6baacd6d456a89851c9743ba56eb
Autor:
Sarah E. Gullbrand, Beth G. Ashinsky, Alon Lai, Jennifer Gansau, James Crowley, Carla Cunha, Julie B. Engiles, Marion Fusellier, Carol Muehleman, Matthew Pelletier, Steven Presciutti, Jordy Schol, Yoshiki Takeoka, Takashi Yurube, Yejia Zhang, Koichi Masuda, James C. Iatridis
Publikováno v:
JOR Spine, Vol 4, Iss 2, Pp n/a-n/a (2021)
Abstract Background The rabbit lumbar spine is a commonly utilized model for studying intervertebral disc degeneration and for the pre‐clinical evaluation of regenerative therapies. Histopathology is the foundation for which alterations to disc mor
Externí odkaz:
https://doaj.org/article/b3459f50ee684517ac802771d06a3cf6
Autor:
Alon Lai, Jennifer Gansau, Sarah E. Gullbrand, James Crowley, Carla Cunha, Stefan Dudli, Julie B. Engiles, Marion Fusellier, Raquel M. Goncalves, Daisuke Nakashima, Jeffrey Okewunmi, Matthew Pelletier, Steven M. Presciutti, Jordy Schol, Yoshiki Takeoka, Sidong Yang, Takashi Yurube, Yejia Zhang, James C. Iatridis
Publikováno v:
JOR Spine, Vol 4, Iss 2, Pp n/a-n/a (2021)
Abstract Background Rats are a widely accepted preclinical model for evaluating intervertebral disc (IVD) degeneration and regeneration. IVD morphology is commonly assessed using histology, which forms the foundation for quantifying the state of IVD
Externí odkaz:
https://doaj.org/article/701a2b7974e448fda80b7a31a3170428
Autor:
Yulong Wei, Hao Sun, Tao Gui, Lutian Yao, Leilei Zhong, Wei Yu, Su-Jin Heo, Lin Han, Nathaniel A Dyment, Xiaowei Sherry Liu, Yejia Zhang, Eiki Koyama, Fanxin Long, Miltiadis H Zgonis, Robert L Mauck, Jaimo Ahn, Ling Qin
Publikováno v:
eLife, Vol 10 (2021)
Meniscal tears are associated with a high risk of osteoarthritis but currently have no disease-modifying therapies. Using a Gli1 reporter line, we found that Gli1+ cells contribute to the development of meniscus horns from 2 weeks of age. In adult mi
Externí odkaz:
https://doaj.org/article/f623562d2d094d8fa2bb24d452a21fa8