Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Yehui Shi"'
Autor:
Jian Zhang, Yiqun Du, Yanchun Meng, Xiaojun Liu, Yuxin Mu, Yunpeng Liu, Yehui Shi, Jufeng Wang, Aimin Zang, Shanzhi Gu, Tianshu Liu, Huan Zhou, Hongqian Guo, Silong Xiang, Xialu Zhang, Suqiong Wu, Huanhuan Qi, Mengke Li, Xichun Hu
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract DP303c is a HER2-targeted ADC with a cleavable linker-MMAE payload. Previous in vitro studies demonstrated that DP303c showed similar or better antitumor activity than T-DM1 in xenograft models. This was a multicenter, dose escalation and do
Externí odkaz:
https://doaj.org/article/e373209687f84f2f8062a4819767885a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
PurposeTriple-negative breast cancer (TNBC) is a highly challenging subtype due to a unique tumor microenvironment. Several evidence (IMpassion130 trial and KEYNOTE-355 trial) supported the therapeutic effect of the immune checkpoint inhibitor in TNB
Externí odkaz:
https://doaj.org/article/901f6abc1a054eb88802dcefa94eb9fc
Autor:
Qiao Li, Dan Lv, Xiaoying Sun, Mengyuan Wang, Li Cai, Feng Liu, Chenghui Li, Jiuda Zhao, Jing Sun, Yehui Shi, Fei Ma
Publikováno v:
Cancer Innovation, Vol 3, Iss 5, Pp n/a-n/a (2024)
Abstract Background We explored the efficacy and safety of inetetamab combined with sirolimus and chemotherapy for the treatment of human epidermal factor receptor 2 (HER2)‐positive metastatic breast cancer patients with abnormal activation of the
Externí odkaz:
https://doaj.org/article/6cff81cea58240268e3dd6e588e6951c
Autor:
Jiani Wang, Zhongsheng Tong, Yinuo Tan, Yehui Shi, Yun Wu, Qing Zhou, Xiaoyan Xing, Xiaomei Chen, Fuming Qiu, Fei Ma
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101707- (2024)
Summary: This phase 1a study assesses ESG401 in patients with heavily pretreated locally advanced or metastatic solid tumors, focusing on metastatic breast cancer. Forty patients are enrolled: three experience dose-limiting toxicities, establishing t
Externí odkaz:
https://doaj.org/article/736f4c38ba8e4e2ca5a20e6083c652d7
Publikováno v:
BioResources, Vol 19, Iss 3, Pp 4250-4263 (2024)
The disposal of agricultural waste ash is a great ecological challenge. This study analyzed the basic properties of corn straw ash and soybean straw ash, encompassing the identification of key oxides, the assessment of particle size distribution, and
Externí odkaz:
https://doaj.org/article/e8464cca9b634b1baf311810c5c3468e
Publikováno v:
Cancer Innovation, Vol 2, Iss 5, Pp 376-390 (2023)
Abstract Background Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype; most cases are triple‐negative breast cancers (TNBCs) and are poorly responsive to conventional systemic therapy. Few potential diagnostic and prognostic marker
Externí odkaz:
https://doaj.org/article/98519e4c2703438095e258e497e3c8f8
Autor:
Yinjuan Li, Lu Qi, Yu Wang, Yan Li, Chunpu Lei, Yingjuan Zhang, Xiaoqiang Cheng, Ju Liu, HaiHong Bai, Xia Zhao, Shuzhen Lv, Bingjun Xiong, Juan Liu, Yehui Shi, Huan Zhou, Hongtao Li, Lihong Liu, Hongchuan Jiang, Weiwei Ouyang, Xiaowen Li, Yanping Li, Xinghe Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeTo compare the pharmacokinetic (PK) bioequivalence (BE) and safety of a generic pegylated liposomal doxorubicin (PLD) formulation with the reference product Caelyx®.MethodsA multicenter, single-dose, open-label, randomized, two-way crossover
Externí odkaz:
https://doaj.org/article/abc1188608a64dcab0fff64f1c96af41
Autor:
Yubei Huang, Zhongsheng Tong, Kexin Chen, Ying Wang, Peifang Liu, Lin Gu, Juntian Liu, Jinpu Yu, Fengju Song, Wenhua Zhao, Yehui Shi, Hui Li, Huaiyuan Xiao, Xishan Hao
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 4, Pp 825-835 (2019)
Breast cancer is the most common malignant tumor in Chinese women. Early screening is the best way to improve the rates of early diagnosis and survival of breast cancer patients. The peak onset age for breast cancer in Chinese women is considerably y
Externí odkaz:
https://doaj.org/article/9c35e9346a38467bb13ad822fbbd345c
Autor:
Xu Wang MM, Yehui Shi MD, Yongsheng Jia MD, Weipeng Zhao MD, Li Zhang MD, Guiying Bai MM, Yulin Ren MM, Yong-Zi Chen PhD, Zhongsheng Tong MM
Publikováno v:
Technology in Cancer Research & Treatment, Vol 20 (2021)
Objective : This study aimed to investigate the tolerance and pharmacokinetic characteristics of recombinant human endostatin (rh-endostatin) administered as single-dose or multiple-dose infusions in patients with advanced solid tumors. Methods : Thi
Externí odkaz:
https://doaj.org/article/05d6a54ddabb4ee9a0628d134572ce97
Autor:
Zhichao Liao, Feng Li, Chao Zhang, Lei Zhu, Yehui Shi, Gang Zhao, Xu Bai, Shafat Hassan, Xinyue Liu, Ting Li, Peipei Xing, Jun Zhao, Jin Zhang, Ruwei Xing, Sheng Teng, Yun Yang, Kexin Chen, Jilong Yang
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 3, Pp 1-11 (2019)
Cancer: Starving sarcomas into submission A drug that inhibits blood vessel growth offers a potentially promising treatment for a class of tumors with a poor prognosis. Sarcomas form in bone and connective tissue, and patients with advanced disease h
Externí odkaz:
https://doaj.org/article/47373e8785a54132934e2a266ec18ce4