Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Yehudit Bergman"'
Autor:
Ihab Ansari, Llorenç Solé-Boldo, Meshi Ridnik, Julian Gutekunst, Oliver Gilliam, Maria Korshko, Timur Liwinski, Birgit Jickeli, Noa Weinberg-Corem, Michal Shoshkes-Carmel, Eli Pikarsky, Eran Elinav, Frank Lyko, Yehudit Bergman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract TET2/3 play a well-known role in epigenetic regulation and mouse development. However, their function in cellular differentiation and tissue homeostasis remains poorly understood. Here we show that ablation of TET2/3 in intestinal epithelial
Externí odkaz:
https://doaj.org/article/cbb5a9ce71a14585b4a2f3a138ff783a
Autor:
Victoria L. Campodónico, Tsigereda Tekle, Yehudit Bergman, Jennifer Lu, Emily Gisriel, Mark Romagnoli, Dimitrios Bourdas, Ann Hanlon, Carmila Manuel, Romney Humphries, Patricia J. Simner, Karen C. Carroll
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Nosocomiicoccus species are infrequently isolated from clinical specimens and their clinical significance has not been evaluated. We retrospectively reviewed five cases in which Nosocomiicoccus ampullae was identified in a single blood cultu
Externí odkaz:
https://doaj.org/article/47e794a188fe46ffa4be2e5f5e7b17a2
Autor:
Rick Conzemius, Yehudit Bergman, Peter Májek, Stephan Beisken, Shawna Lewis, Emily B. Jacobs, Pranita D. Tamma, Patricia J. Simner
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Whole-genome sequencing (WGS) enables the molecular characterization of bacterial pathogens. We compared the accuracy of the Illumina and Oxford Nanopore Technologies (ONT) sequencing platforms for the determination of AMR classes and antimicrobial s
Externí odkaz:
https://doaj.org/article/f83d6a54745843d9b0d3ec3980632196
Autor:
Britny Blumenfeld, Hagit Masika, Marganit Farago, Yishai Yehuda, Lamia Halaseh, Oriya Vardi, Rachel Rapoport, Rena Levin-Klein, Howard Cedar, Yehudit Bergman, Itamar Simon
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Most regions of the mammalian genome replicate both alleles in a synchronous manner, but some loci have been found to replicate asynchronously and the time of replication of each allele is different. Here the authors, by employing clonal mouse cells
Externí odkaz:
https://doaj.org/article/5a44785bc8d24207acd6f75995d67d94
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Developmental programming is carried out by a sequence of molecular choices that epigenetically mark the genome to generate the stable cell types which make up the total organism. A number of important processes, such as genomic imprinting, selection
Externí odkaz:
https://doaj.org/article/77db64bdcf0b41d78b52521cad53f925
Autor:
Jay Vornhagen, Christine M Bassis, Srividya Ramakrishnan, Robert Hein, Sophia Mason, Yehudit Bergman, Nicole Sunshine, Yunfan Fan, Caitlyn L Holmes, Winston Timp, Michael C Schatz, Vincent B Young, Patricia J Simner, Michael A Bachman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009537 (2021)
Klebsiella pneumoniae (Kp) is an important cause of healthcare-associated infections, which increases patient morbidity, mortality, and hospitalization costs. Gut colonization by Kp is consistently associated with subsequent Kp disease, and patients
Externí odkaz:
https://doaj.org/article/fa3d3e515da74a689ac27b6245f842d6
Autor:
Heba H. Mostafa, John A. Fissel, Brian Fanelli, Yehudit Bergman, Victoria Gniazdowski, Manoj Dadlani, Karen C. Carroll, Rita R. Colwell, Patricia J. Simner
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Metagenomic next-generation sequencing (mNGS) offers an agnostic approach for emerging pathogen detection directly from clinical specimens. In contrast to targeted methods, mNGS also provides valuable information on the composition of the mi
Externí odkaz:
https://doaj.org/article/d01779a07c43439b81d8ca2d910f33a3
Autor:
Felix Bormann, Manuel Rodríguez-Paredes, Felix Lasitschka, Dominic Edelmann, Tanja Musch, Axel Benner, Yehudit Bergman, Sebastian M. Dieter, Claudia R. Ball, Hanno Glimm, Heinz G. Linhart, Frank Lyko
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3407-3418 (2018)
Summary: Colorectal adenomas are precursor lesions of colorectal cancers and represent clonal amplifications of single cells from colonic crypts. DNA methylation patterns specify cell-type identity during cellular differentiation and, therefore, prov
Externí odkaz:
https://doaj.org/article/e86c318f3a9a4f9bb5b8774c69ab0e1e
Autor:
Marise R. Heerma van Voss, Kai Kammers, Farhad Vesuna, Justin Brilliant, Yehudit Bergman, Saritha Tantravedi, Xinyan Wu, Robert N. Cole, Andrew Holland, Paul J. van Diest, Venu Raman
Publikováno v:
Translational Oncology, Vol 11, Iss 3, Pp 755-763 (2018)
DDX3 is an RNA helicase with oncogenic properties. The small molecule inhibitor RK-33 is designed to fit into the ATP binding cleft of DDX3 and hereby block its activity. RK-33 has shown potent activity in preclinical cancer models. However, the mech
Externí odkaz:
https://doaj.org/article/918397a6c22c42c89f0d469467e5637f
Autor:
Rena Levin-Klein, Shira Fraenkel, Michal Lichtenstein, Louise S. Matheson, Osnat Bartok, Yuval Nevo, Sebastian Kadener, Anne E. Corcoran, Howard Cedar, Yehudit Bergman
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
B cell development involves sequential rearrangement of the immunoglobulin chains, but fine control over the selection process remains a mystery. Here the authors show that individual alleles in pre-B cells are clonally unique and result from stochas
Externí odkaz:
https://doaj.org/article/a60058be570b46449a317fcb6741376b