Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Yehuda Z. Patt"'
Publikováno v:
Liver Cancer. 4:70-83
Background and Aims: Hepatocellular carcinoma (HCC) incidence is expected to rise dramatically over the next decades because of increasing hepatitis C infections and obesity-related comorbidities. However, little information exists regarding the trea
Autor:
Emilio P. Araujo‐Mino, Yehuda Z. Patt, M. Houman Fekrazad, Ben J. Liem, Ashwani Rajput, Cristina Murray‐Krezan, Fa-Chyi Lee, Glenory Heywood, Joshua A. Hanson, Pranshu Bansal
Publikováno v:
The Oncologist
Lessons Learned Colorectal cancers exhibit a high level of cyclooxygenase-2 (COX-2) expression with strong preclinical rationale for improved clinical outcomes with COX-2 inhibition. Celecoxib is a COX-2 inhibitor and we have shown that it can be saf
Autor:
Houman Mohammad Fekrazad, Pranshu Bansal, Yehuda Z. Patt, Cristhiam M. Rojas-Hernandez, Fa-Chyi Lee
Publikováno v:
The Oncologist
Lessons Learned There continues to be a lack of systemic options for advanced hepatocellular carcinoma (HCC); sorafenib and, very recently, regorafenib are the only approved options. There exists a potential to combine sorafenib with chemotherapeutic
Autor:
Jeffrey S. Morris, Sahin Lacin, Prasun K. Jalal, Robert A. Wolff, Ahmed Omar Kaseb, Reham Abdel-Wahab, Harrys A. Torres, Saira Khaderi, John A. Goss, Ernest T. Hawk, Yasmin Abaza, Ahmed S Shalaby, Yehuda Z. Patt, Hesham M. Hassabo, Renato Lenzi, Christopher I. Amos, Alexandria T. Phan, Manal Hassan, David J. Tweardy, Asif Rashid, Donghui Li, Milind Javle, Gehan Botrus, Ju Seog Lee
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 15(11)
Background & Aims Environmental factors have been identified that affect risk of hepatocellular carcinoma (HCC), but little is known about the effects of sex hormones on liver cancer development or outcome. The authors investigated whether menopause
Autor:
Yehuda Z. Patt, Kim A. Steinberg, Edward J. Bedrick, Waheed Murad, Ruofei Du, Sang Joon Lee, Fa-Chyi Lee, Pranshu Bansal, Ari D. Baron, Mohammed H. Fekrazad, Yanis Boumber
Publikováno v:
Cancer Medicine
Hepatocellular Carcinoma (HCC) incidence is increasing in the USA. Gemcitabine (G) and oxaliplatin (O) are active in HCC and biliary duct cancer (BDC). Erlotinib (E) is an EGFR tyrosine kinase inhibitor (TKI) with known activity against both. We soug
Autor:
Yehuda Z. Patt, Thomas A. Aloia, James L. Abbruzzese, Jean Nicolas Vauthey, Hesham M. Hassabo, Manal M. Hassan, Richard D. Lozano, Junichi Shindoh, Robert E. Roses, Ahmed Kaseb, Steven A. Curley, Giuseppe Zimmitti
Publikováno v:
Cancer. 119:3334-3342
BACKGROUND The purpose of this study was to evaluate the factors associated with response rate, resectability, and survival after cisplatin/interferon α-2b/doxorubicin/5-fluorouracil (PIAF) combination therapy in patients with initially unresectable
Autor:
Carol J. Etzel, Asif Rashid, James L. Abbruzzese, Curtis J. Wray, Ernest T. Hawk, Jean Nicolas Vauthey, Hashem B. El-Serag, Mohamed A. Shama, Harmeet Kaur, Yehuda Z. Patt, Donghui Li, Hesham M. Hassabo, Margaret R. Spitz, Ping Chang, Mei Liu, Manal M. Hassan, Basmah S. Hassan, Ahmed O. Kaseb, Khalid Soliman, Evelyne M. Loyer, Katherine S. Hale
Publikováno v:
Molecular Carcinogenesis. 52:139-147
Nonalcoholic fatty liver disease (NAFLD) is an emerging epidemic with high prevalence in Western countries. Genome-wide association studies had reported that a variation in the patatin-like phospholipase domain containing 3 (PNPLA3) gene is associate
Autor:
Alexandria T. Phan, Robert A. Wolff, Yasmin Abaza, Ahmed Omar Kaseb, Ibrahim Halil Sahin, Jeffrey S. Morris, Yehuda Z. Patt, Ahmed S Shalaby, Manal Hassan, Donghui Li, Kanwal Pratap Singh Raghav, Ernest T. Hawk, Reham Abdel-Wahab
Publikováno v:
Journal of Epidemiological Research. 3
Background: Hepatocellular carcinoma (HCC) has many well-known predisposing factors including viral hepatitis, alcoholconsumption, metabolic syndrome, and cigarette smoking. However, about 30%-40% of patients have no identifiable risk factor, indicat
Autor:
Sylvia Hu, Thomas Cartwright, Herbert Hurwitz, Edward McKenna, Ambrose Kwok, Yehuda Z. Patt, Edith P. Mitchell
Publikováno v:
The Oncologist. 17:937-946
Background. Capecitabine administered for 7 days biweekly with oxaliplatin (XELOX) biweekly has been reported to have activity and safety profiles similar to those of standard capecitabine given for 14 days triweekly. Multiple studies have shown that
Autor:
Mark M. Zalupski, Robert T. Dorr, Yehuda Z. Patt, Evan M. Hersh, Paul Conkling, Peg Davis, Michelle L. Boytim, Manuel Modiano, Steven J. Cohen
Publikováno v:
Cancer Chemotherapy and Pharmacology. 66:287-294
Imexon is an aziridine-derived iminopyrrolidone which has synergy with gemcitabine in pancreatic cancer cell lines. Gemcitabine is a standard therapy for pancreatic cancer. We performed a phase I trial of imexon and gemcitabine to evaluate safety, do