Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yehuda, Brody"'
Autor:
Jair Bar, Raya Leibowitz, Niels Reinmuth, Astrid Ammendola, Eyal Jacob, Mor Moskovitz, Adva Levy-Barda, Michal Lotem, Rivka Katsenelson, Abed Agbarya, Mahmoud Abu-Amna, Maya Gottfried, Tatiana Harkovsky, Ido Wolf, Ella Tepper, Gil Loewenthal, Ben Yellin, Yehuda Brody, Nili Dahan, Maya Yanko, Coren Lahav, Michal Harel, Shani Raveh Shoval, Yehonatan Elon, Itamar Sela, Adam P. Dicker, Yuval Shaked
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmune checkpoint inhibitors have made a paradigm shift in the treatment of non-small cell lung cancer (NSCLC). However, clinical response varies widely and robust predictive biomarkers for patient stratification are lacking. Here, we cha
Externí odkaz:
https://doaj.org/article/926af04f4d0440e18244af89ddf7f699
Autor:
Elad Jacoby, Moriya Ben Yakir-Blumkin, Shiri Blumenfeld-Kan, Yehuda Brody, Amilia Meir, Naomi Melamed-Book, Tina Napso, Gat Pozner, Esraa Saadi, Ayelet Shabtay-Orbach, Natalie Yivgi-Ohana, Noa Sher, Amos Toren
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Mitochondria are cellular organelles critical for numerous cellular processes and harboring their own circular mitochondrial DNA (mtDNA). Most mtDNA associated disorders (either deletions, mutations, or depletion) lead to multisystemic disea
Externí odkaz:
https://doaj.org/article/ea28dd8efa07497c88f0f158a175ba5b
Autor:
Megan Shand, Jose Soto, Lee Lichtenstein, David Benjamin, Yossi Farjoun, Yehuda Brody, Yosef Maruvka, Paul C. Blainey, Eric Banks
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-8 (2020)
Megan Shand et al. present Lineage derived Somatic Truth (LinST), a validated data set of somatic mutations from a colon cancer cell line with a known lineage tree structure. They show that LinST can be used to benchmark true-positive and false-posit
Externí odkaz:
https://doaj.org/article/ac5e932b4eb24213a2667a14bb688207
Autor:
Naama Sebbag-Sznajder, Yehuda Brody, Hodaya Hochberg-Laufer, Yaron Shav-Tal, Joseph Sperling, Ruth Sperling
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Splicing and alternative splicing of pre-mRNA are key sources in the formation of diversity in the human proteome. These processes have a central role in the regulation of the gene expression pathway. Yet, how spliceosomes are assembled on a multi-in
Externí odkaz:
https://doaj.org/article/d5c586630ffd41038fe7ba677882f0c0
Autor:
Hodaya Hochberg-Laufer, Noa Neufeld, Yehuda Brody, Shani Nadav-Eliyahu, Rakefet Ben-Yishay, Yaron Shav-Tal
Publikováno v:
PLoS Genetics, Vol 15, Iss 11, p e1008459 (2019)
Gene expression dynamics can be measured in single living cells. Using a detectable transcriptionally active gene in living cells, we previously found that an mRNA undergoing several splicing events was retained at this gene after transcription until
Externí odkaz:
https://doaj.org/article/20f5516af9214947be87cc631baa8d44
Autor:
Ayelet Shabtay-Orbach, Elad Jacoby, Amilia Meir, Amos Toren, Noa Sher, Esraa Saadi, Natalie Yivgi-Ohana, Gat Pozner, Moriya Ben Yakir-Blumkin, Shiri Blumenfeld-Kan, Tina Napso, Naomi Melamed-Book, Yehuda Brody
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Mitochondria are cellular organelles critical for numerous cellular processes and harboring their own circular mitochondrial DNA (mtDNA). Most mtDNA associated disorders (either deletions, mutations, or depletion) lead to multisystemic disease, often
Publikováno v:
BioTechniques, Vol 39, Iss 2, Pp 180-184 (2005)
Externí odkaz:
https://doaj.org/article/a9a77e31b8354078a890f74bcd3288a8
Autor:
Tom Domovich, Meital Gal-Tanamy, Michael Gevor, Assam El-Osta, Tomer Meirson, Yehuda Brody, Ateret Davidovich, Avi Matityahu, Katreena Yamin, Shira Perez, Izhak Haviv, Antony Kaspi, Itay Onn, Salomon M. Stemmer
Publikováno v:
Nucleic Acids Research
Hepatitis C virus (HCV) infection is the leading cause of chronic hepatitis, which often results in liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). HCV possesses an RNA genome and its replication is confined to the cytoplasm. Yet, infec
Autor:
Hodaya Hochberg-Laufer, Yehuda Brody, Yaron Shav-Tal, Naama Sebbag-Sznajder, Ruth Sperling, Joseph Sperling
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics
Frontiers in Genetics
Splicing and alternative splicing of pre-mRNA are key sources in the formation of diversity in the human proteome. These processes have a central role in the regulation of the gene expression pathway. Yet, how spliceosomes are assembled on a multi-in
Autor:
Lee Lichtenstein, Yossi Farjoun, Jose Soto, Paul C. Blainey, David Benjamin, Yehuda Brody, Eric Banks, Megan Shand, Yosef E. Maruvka
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-8 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-8 (2020)
Existing cancer benchmark data sets for human sequencing data use germline variants, synthetic methods, or expensive validations, none of which are satisfactory for providing a large collection of true somatic variation across a whole genome. Here we