Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Yeh-Hsing Lao"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The membrane-fusion-based internalization without lysosomal entrapment is advantageous for intracellular delivery over endocytosis. However, protein corona formed on the membrane-fusogenic liposome surface converts its membrane-fusion perfor
Externí odkaz:
https://doaj.org/article/76aafc06823146b795b3c62c5c47ae9b
Autor:
Yuanyuan Jin, Jiabin Zhang, Yanteng Xu, Ke Yi, Fenfang Li, Huicong Zhou, Haixia Wang, Hon Fai Chan, Yeh-Hsing Lao, Shixian Lv, Yu Tao, Mingqiang Li
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 112-131 (2023)
Reactive oxygen species (ROS)-associated oxidative stress, inflammation storm, and massive hepatocyte necrosis are the typical manifestations of acute liver failure (ALF), therefore specific therapeutic interventions are essential for the devastating
Externí odkaz:
https://doaj.org/article/9d76953081d14a12a517610f55416961
Autor:
Hanyao Huang, Weiyi Pan, Yifan Wang, Hye Sung Kim, Dan Shao, Baoding Huang, Tzu-Chieh Ho, Yeh-Hsing Lao, Chai Hoon Quek, Jiayu Shi, Qianming Chen, Bing Shi, Shengmin Zhang, Lei Zhao, Kam W. Leong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Periodontitis is a common type of inflammatory bone loss, and cell-free DNA (cfDNA) can be a major source that enhances the periodontal tissue destruction. Here, the authors show that a cfDNA-scavenging approach is able to ameliorate periodontitis by
Externí odkaz:
https://doaj.org/article/93703e2f9a7c40a7b3a4f9319e5fd435
Autor:
Huimin Kong, Enguo Ju, Ke Yi, Weiguo Xu, Yeh‐Hsing Lao, Du Cheng, Qi Zhang, Yu Tao, Mingqiang Li, Jianxun Ding
Publikováno v:
Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)
Abstract Liver disease, particularly viral hepatitis and hepatocellular carcinoma (HCC), is a global healthcare burden and leads to more than 2 million deaths per year worldwide. Despite some success in diagnosis and vaccine development, there are st
Externí odkaz:
https://doaj.org/article/37bcfc3ff94b40c28078c55a4e3d79be
Autor:
Hanze Hu, Chao Yang, Fan Zhang, Mingqiang Li, Zhaoxu Tu, Lizhong Mu, Jianati Dawulieti, Yeh‐Hsing Lao, Zixuan Xiao, Huize Yan, Wen Sun, Dan Shao, Kam W. Leong
Publikováno v:
Advanced Science, Vol 8, Iss 15, Pp n/a-n/a (2021)
Abstract Biomimetic strategies are useful for designing potent vaccines. Decorating a nanoparticulate adjuvant with cell membrane fragments as the antigen‐presenting source exemplifies, such as a promising strategy. For translation, a standardizabl
Externí odkaz:
https://doaj.org/article/b4af12d948e04ff2b7e38c368dde701a
Autor:
Rachel L. Mintz, Yeh‐Hsing Lao, Chun‐Wei Chi, Siyu He, Mingqiang Li, Chai Hoon Quek, Dan Shao, Boyuan Chen, Jing Han, Sihong Wang, Kam W. Leong
Publikováno v:
Bioengineering & Translational Medicine, Vol 5, Iss 1, Pp n/a-n/a (2020)
Abstract For patients carrying BRCA1 mutations, at least one‐third develop triple negative breast cancer (TNBC). Not only is TNBC difficult to treat due to the lack of molecular target receptors, but BRCA1 mutations (BRCA1m) also result in chemothe
Externí odkaz:
https://doaj.org/article/8aa2dd66bd4e4311a93ad83ab768f12f
Publikováno v:
Advanced Science, Vol 6, Iss 15, Pp n/a-n/a (2019)
Abstract Inflammation is ubiquitous in the body, triggering desirable immune response to defend against dangerous signals or instigating undesirable damage to cells and tissues to cause disease. Nanomedicine holds exciting potential in modulating inf
Externí odkaz:
https://doaj.org/article/70b3f99507e14085bf833ff246ca83f7
Publikováno v:
Biomaterials Science (2047-4830); 5/7/2024, Vol. 12 Issue 9, p2203-2228, 26p
Autor:
Naoto Yoshinaga, Joyce K. Zhou, Cong Xu, Chai Hoon Quek, Yuefei Zhu, Ding Tang, Lin Yung Hung, Sarah A. Najjar, Chin Ying Angela Shiu, Kara Gross Margolis, Yeh-Hsing Lao, Kam W. Leong
Publikováno v:
Nano Letters. 23:757-764
Autor:
Kam Leong, Yeh-Hsing Lao, Robin Ji, Joyce Zhou, Kathy Snow, Nancy Kwon, Ethan Saville, Siyu He, Shradha Chauhan, Chun-Wei Chi, Malika Datta, Hairong Zhang, Chai Hoon Quek, Sarah Cai, Mingqiang Li, Yaned Gaitan, Lawrence Bechtel, Shih-Ying Wu, Cathleen Lutz, Raju Tomer, Stephen Murray, Alejandro Chavez, Elisa Konofagou
Gene editing in the mammalian brain has been challenging because of the restricted transport imposed by the blood-brain barrier (BBB). Current approaches rely on local injection to bypass the BBB. However, such administration is highly invasive and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29af02a572d5897ea4f72b06cf473300
https://doi.org/10.21203/rs.3.rs-2365576/v1
https://doi.org/10.21203/rs.3.rs-2365576/v1