Abstract 1642: Calponin-3, acidic (CNN3) mediates EMT-related genes in human colorectal cancer metastasis

Autor: Jea-Gab Park, Soon-Chan Kim, Sang-Geun Jang, Chang-Won Hong, Seung-Yong Jung, Yeh-Ah Kim, Ja-Lok Ku

Publikováno v: Cancer Research. 76:1642-1642

(a) An introductory sentence indicating the purposes of the study Distant metastasis is the major cause of cancer-related death in colorectal cancer (CRC) patients. Although the Calponin family has emerged as a distinguishing feature in epithelial-to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcd9389b501671ca0ae3ed9ccb819e75
https://doi.org/10.1158/1538-7445.am2016-1642

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De novo design of high-affinity binders of bioactive helical peptides.

Autor: Vázquez Torres S; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Biological Physics, Structure and Design, University of Washington, Seattle, WA, USA., Leung PJY; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Venkatesh P; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Biological Physics, Structure and Design, University of Washington, Seattle, WA, USA., Lutz ID; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Bioengineering, University of Washington, Seattle, WA, USA., Hink F; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Huynh HH; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Becker J; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Yeh AH; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Juergens D; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Bennett NR; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Hoofnagle AN; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Huang E; Department of Genome Sciences, University of Washington, Seattle, WA, USA., MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Expòsit M; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA., Lee GR; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Bera AK; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Kang A; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., De La Cruz J; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Levine PM; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Li X; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Lamb M; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Gerben SR; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Murray A; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Heine P; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Korkmaz EN; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Nivala J; School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.; Molecular Engineering and Sciences Institute, University of Washington, Seattle, WA, USA., Stewart L; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Watson JL; Department of Biochemistry, University of Washington, Seattle, WA, USA. jwatson3@uw.edu.; Institute for Protein Design, University of Washington, Seattle, WA, USA. jwatson3@uw.edu., Rogers JM; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. joseph.rogers@sund.ku.dk., Baker D; Department of Biochemistry, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Institute for Protein Design, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA. dabaker@uw.edu.

Publikováno v: Nature [Nature] 2024 Feb; Vol. 626 (7998), pp. 435-442. Date of Electronic Publication: 2023 Dec 18.

HCC EV ECG score: An extracellular vesicle-based protein assay for detection of early-stage hepatocellular carcinoma.

Autor: Sun N; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA.; Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics , University of Chinese Academy of Sciences, Chinese Academy of Sciences , Suzhou , People's Republic of China., Zhang C; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA.; Department of Pathology, Basic Medical College , Southern Medical University , Guangzhou , People's Republic of China., Lee YT; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Tran BV; Department of Surgery, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Wang J; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Kim H; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Lee J; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Zhang RY; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Wang JJ; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA.; Division of Medical Oncology, Department of Medicine , Cedars-Sinai Medical Center , Los Angeles , California , USA., Hu J; Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Zhang Z; Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Alsudaney MS; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA., Hou KC; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Tang H; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Zhang TX; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Liang IY; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Zhou Z; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Chen M; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Yeh AH; Department of Medicine, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Li W; Department of Pathology and Laboratory Medicine, Ronald Reagan Medical Center, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Zhou XJ; Department of Pathology and Laboratory Medicine, Ronald Reagan Medical Center, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Chang HR; Department of Surgery, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Han SB; Department of Medicine, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Sadeghi S; Department of Medicine, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Finn RS; Department of Medicine, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Saab S; Department of Medicine, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Busuttil RW; Department of Surgery, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Noureddin M; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA., Ayoub WS; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA., Kuo A; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA., Sundaram V; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA., Al-Ghaieb B; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA., Palomique J; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA., Kosari K; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA., Kim IK; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA., Todo T; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA., Nissen NN; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA., Tomasi ML; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA., You S; Departments of Surgery and Biomedical Sciences , Cedars-Sinai Medical Center , Los Angeles , California , USA., Posadas EM; Division of Medical Oncology, Department of Medicine , Cedars-Sinai Medical Center , Los Angeles , California , USA., Wu JX; Department of Surgery, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Wadehra M; Department of Pathology and Laboratory Medicine, Ronald Reagan Medical Center, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Sim MS; Department of Medicine, Statistics Core, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Li Y; Department of Pathology and Laboratory Medicine, Ronald Reagan Medical Center, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Wang HL; Department of Pathology and Laboratory Medicine, Ronald Reagan Medical Center, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., French SW; Department of Pathology and Laboratory Medicine, Ronald Reagan Medical Center, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA., Lu SC; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Samuel Oschin Comprehensive Cancer Institute , Cedars-Sinai Medical Center , Los Angeles , California , USA., Wu L; Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA., Pei R; Key Laboratory for Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics , University of Chinese Academy of Sciences, Chinese Academy of Sciences , Suzhou , People's Republic of China., Liang L; Department of Pathology, Nanfang Hospital and Basic Medical College , Southern Medical University , Guangzhou , People's Republic of China.; Guangdong Province Key Laboratory of Molecular Tumor Pathology , Guangzhou , People's Republic of China., Yang JD; Comprehensive Transplant Center , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Karsh Division of Gastroenterology and Hepatology , Cedars-Sinai Medical Center , Los Angeles , California , USA.; Samuel Oschin Comprehensive Cancer Institute , Cedars-Sinai Medical Center , Los Angeles , California , USA., Agopian VG; Department of Surgery, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA.; Jonsson Comprehensive Cancer Center , University of California, Los Angeles , Los Angeles , California , USA., Tseng HR; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA.; Jonsson Comprehensive Cancer Center , University of California, Los Angeles , Los Angeles , California , USA., Zhu Y; California NanoSystems Institute, Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology , University of California, Los Angeles , Los Angeles , California , USA.; Department of Pathology and Laboratory Medicine, Ronald Reagan Medical Center, David Geffen School of Medicine , University of California, Los Angeles , Los Angeles , California , USA.; Jonsson Comprehensive Cancer Center , University of California, Los Angeles , Los Angeles , California , USA.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2023 Mar 01; Vol. 77 (3), pp. 774-788. Date of Electronic Publication: 2023 Feb 17.