Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yefang Zou"'
Autor:
Fang Wang, Chun Wang, Jie Wang, Yefang Zou, Xiaoxue Chen, Ting Liu, Yan Li, Yonglong Zhao, Yongjun Li, Bin He
Publikováno v:
Royal Society Open Science, Vol 6, Iss 6 (2019)
HDAC inhibitors have been developed very rapidly in clinical trials and even in approvals for treating several cancers. However, there are few reported HDAC inhibitors designed from Nɛ-acetyl lysine. In the current study, we raised a novel design, w
Externí odkaz:
https://doaj.org/article/f493a2bb0afd4a09b70b28c7cfe57dbb
Publikováno v:
Annals of palliative medicine. 10(9)
BACKGROUND The training of orthopedic nurse specialists is gradually increasing in China, but the effect of the training, namely the specialized nursing work carried out by them upon returning to work after training, is unknown. This study aimed to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b8941add0917a29be43a85070a1d07
https://pubmed.ncbi.nlm.nih.gov/34628874
https://pubmed.ncbi.nlm.nih.gov/34628874
Publikováno v:
Experimental Oncology; Jun2022, Vol. 44 Issue 2, p126-131, 6p
Autor:
Bin He, Jie Wang, Xiaoxue Chen, Yong-Long Zhao, Ai-Min Wang, Zhuoxian Cao, Yan Li, Jingzi Liu, Yefang Zou, Yan-Qin Chen
Publikováno v:
Chemicalpharmaceutical bulletin. 68(7)
Although anthraquinone derivatives possess significant antitumor activity, most of them also displayed those side effects like cardiotoxicity, mainly owing to their inhibition of topoisomerase II of DNA repair mechanisms. Our raised design strategy b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115c334253c0624223c820c146f7b9ca
https://pubmed.ncbi.nlm.nih.gov/32611998
https://pubmed.ncbi.nlm.nih.gov/32611998
Publikováno v:
Bioorganicmedicinal chemistry. 28(6)
A series of sirtuin inhibitor candidates were assembled based on an intermediate ester (1a) our accidently discovered. After screening and evaluation, several SIRT2 selective inhibitors were identified, which can inhibit all the deacetylation, defatt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeb5943ac902a7412c85e39185c5b51
https://pubmed.ncbi.nlm.nih.gov/32061485
https://pubmed.ncbi.nlm.nih.gov/32061485
Autor:
Yongjun Li, Yan Li, Bin He, Xiaoxue Chen, Qingjie Zhao, Yefang Zou, Jingshan Shen, Fang Wang, Wang Chun, Hong Zhu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2375-2378
Sirtuin inhibitors as physiological research tools and therapeutic potentials have caught many attentions in last decades. The mimics of acyl lysine have been approved to be a very efficient strategy for development of mechanism-based sirtuin inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f3853689a0648c422ed41549069e35
https://doi.org/10.1016/j.bmcl.2018.06.030
https://doi.org/10.1016/j.bmcl.2018.06.030
Autor:
Wang, Fang, Wang, Chun, Wang, Jie, Yefang Zou, Xiaoxue Chen, Liu, Ting, Li, Yan, Yonglong Zhao, Yongjun Li, He, Bin
HDAC inhibitors have been developed very rapidly in clinical trials and even in approvals for treating several cancers. However, there are few reported HDAC inhibitors designed from Nε-acetyl lysine. In current study, we raised a novel design, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366c43e39b128a0811daaf348db150e3
Autor:
Chun, Wang, Fang, Wang, Xiaoxue, Chen, Yefang, Zou, Hong, Zhu, Qingjie, Zhao, Jingshan, Shen, Yan, Li, Yongjun, Li, Bin, He
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(14)
Sirtuin inhibitors as physiological research tools and therapeutic potentials have caught many attentions in last decades. The mimics of acyl lysine have been approved to be a very efficient strategy for development of mechanism-based sirtuin inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7586b2718bffa073cf924d76077f393b
https://pubmed.ncbi.nlm.nih.gov/29921476
https://pubmed.ncbi.nlm.nih.gov/29921476