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pro vyhledávání: '"Yee Wa Lim"'
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7151 (2020)
RNA-binding proteins (RBPs) are a class of proteins known for their diverse roles in RNA biogenesis, from regulating transcriptional processes in the nucleus to facilitating translation in the cytoplasm. With higher demand for RNA metabolism in the n
Externí odkaz:
https://doaj.org/article/9a6ac1832b4f4e18940e49d4f13256dc
Autor:
Mihwa Lee, Mitchell T Ringuet, Victor Anggono, Jie Huang, Rahul Badhan, Andrew E. Whitten, Yee Wa Lim, Sofia Caria
Publikováno v:
Nucleic Acids Research
SFPQ is a ubiquitous nuclear RNA-binding protein implicated in many aspects of RNA biogenesis. Importantly, nuclear depletion and cytoplasmic accumulation of SFPQ has been linked to neuropathological conditions such as Alzheimer's disease (AD) and am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe1954550bdcd0cd2b6b3a17b94083e
http://europepmc.org/articles/PMC7102971
http://europepmc.org/articles/PMC7102971
Autor:
Mihwa Lee, Yee Wa Lim
Publikováno v:
Protein Expression and Purification. 171:105626
Splicing factor proline- and glutamine-rich (SFPQ) is an RNA-binding protein, playing significant roles in gene regulation and subnuclear body formation. Our recent serendipitous discovery showed that SFPQ binds zinc directly and forms an infinite po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f8892dd94735234127161c408d2978
https://doi.org/10.1016/j.pep.2020.105626
https://doi.org/10.1016/j.pep.2020.105626