Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yee Ping Ho"'
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 14:756-761
The different types of cell death occurring in HCT116 colorectal cancer cell after the treatment of cisplatin, carboplatin, oxaliplatin, DMC, Pt(NH3)2(demethylcantharidin:DMC) and Pt(R,R-1,2-diaminocyclohexane: DACH)(DMC) were examined. Pt(NH3)2(DMC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d3d4de272d5e06381505b49299403d
https://doi.org/10.2174/1871520614666140127104057
https://doi.org/10.2174/1871520614666140127104057
Publikováno v:
Phytotherapy Research. 24:1538-1542
Amyloid β peptide (Aβ) induced toxicity is a well-established pathway of neuronal cell death which might play a role in Alzheimer's disease. In this regard, the toxic effect of Aβ on a cultured Aβ-sensitive neuronal cell line was used as a primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3cf572dab676245b7c03efad227266c
https://doi.org/10.1002/ptr.3178
https://doi.org/10.1002/ptr.3178
Publikováno v:
Biochemical and Biophysical Research Communications. 363:235-240
Oxaliplatin is a third generation platinum (Pt) drug with a diaminocyclohexane (DACH) entity, which has recently obtained worldwide approval for the clinical treatment of colon cancer, and apparently operates by a different mechanism of action to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6b6b1b26e64465b6699fe83aa964ec
https://doi.org/10.1016/j.bbrc.2007.08.172
https://doi.org/10.1016/j.bbrc.2007.08.172
Publikováno v:
Journal of Inorganic Biochemistry. 101:909-917
The pharmacokinetics and tissue distribution profiles of a novel series of traditional Chinese medicine-platinum (TCM-Pt) compounds [Pt(C(8)H(8)O(5))(NH(2)R)(2)]: 1 (where R=H), 3 (R=CH(3)) and 5 (R=C(6)H(10)), were studied in Sprague-Dawley rats fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac3ea8b28b927f1e845308147a12bab
https://doi.org/10.1016/j.jinorgbio.2007.02.007
https://doi.org/10.1016/j.jinorgbio.2007.02.007
Publikováno v:
Cancer Letters. 223:227-237
A novel series of TCM-platinum complexes [Pt(C 8 H 8 O 5 )(NH 2 R) 2 ] 1 – 5 , designed from incorporating demethylcantharidin, a modified component from a traditional Chinese medicine (TCM) with a platinum moiety was found to circumvent cisplatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72771179d4b47ec8363b843ced9a44e
https://doi.org/10.1016/j.canlet.2004.10.036
https://doi.org/10.1016/j.canlet.2004.10.036
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:4565-4573
Novel TCM–platinum compounds [Pt(C 8 H 8 O 5 )(NH 2 R) 2 ] 1 – 5 , derived from integrating demethylcantharidin, a modified component from a traditional Chinese medicine (TCM) with a platinum moiety, possess anticancer and protein phosphatase 2A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876a0ff12191aa058ce36721472ae8e4
https://doi.org/10.1016/j.bmc.2004.07.009
https://doi.org/10.1016/j.bmc.2004.07.009
Publikováno v:
Medicinal Research Reviews. 23:633-655
The impact of cisplatin on cancer chemotherapy cannot be denied. Over the past 20 years, much effort has been dedicated to discover new platinum-based anticancer agents that are superior to cisplatin or its analogue, carboplatin. Most structural modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581cba39df96ad9e2bd1d4ba3c11a979
https://doi.org/10.1002/med.10038
https://doi.org/10.1002/med.10038
Publikováno v:
Journal of Chromatography A. 947:319-326
The present paper describes the development of a simple, accurate and reproducible gas chromatographic method for the determination of hydrolyzed demethylcantharidin release from a novel series of traditional Chinese medicine (TCM)–platinum compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c9530dba15c66e56967e5d45a830a2
https://doi.org/10.1016/s0021-9673(01)01611-9
https://doi.org/10.1016/s0021-9673(01)01611-9
Publikováno v:
Journal of Medicinal Chemistry. 44:2065-2068
A combination of demethylcantharidin, a modified component of a traditional Chinese medicine (TCM), with a platinum moiety has produced a series of TCM-based platinum compounds [Pt(C(8)H(8)O(5))(NH(2)R)(2)] 1-5, which demonstrate selective cytotoxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f16f21f053175aed9fc2326f932c1fe
https://doi.org/10.1021/jm000476t
https://doi.org/10.1021/jm000476t
Publikováno v:
Journal of Chromatography A. 873:221-228
The present paper describes the development of a most simple, sensitive, and specific gas chromatographic method to date, for the direct determination of seven major bioactive isosteroidal alkaloids, namely ebeiedine, ebeiedinone, ebeienine, hupeheni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8953177e9cfc45833980f668ed8e4d15
https://doi.org/10.1016/s0021-9673(00)00049-2
https://doi.org/10.1016/s0021-9673(00)00049-2