Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yee Peng, Phoon"'
Autor:
Lukas W Pfannenstiel, Brian R Gastman, Jennifer S Ko, Marc S Ernstoff, Pauline Funchain, Yee Peng Phoon, Jared E Lopes, Heather C Losey, Claudia Marcela Diaz-Montero, Ye F Tian, Raymond Winquist, Jan Joseph Melenhorst
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Despite recent advances in immunotherapy, a substantial population of late-stage melanoma patients still fail to achieve sustained clinical benefit. Lack of translational preclinical models continues to be a major challenge in the field of
Externí odkaz:
https://doaj.org/article/be91f26ce0d14a72a9d770e7782a5e38
Autor:
Cheryl M. Cameron, Brian Richardson, Jackelyn B. Golden, Yee Peng Phoon, Banumathi Tamilselvan, Lukas Pfannenstiel, Samjhana Thapaliya, Gustavo Roversi, Xing-Huang Gao, Leah L. Zagore, Mark J. Cameron, Brian R. Gastman
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSignificant heterogeneity exists within the tumor-infiltrating CD8 T cell population, and exhausted T cells harbor a subpopulation that may be replicating and may retain signatures of activation, with potential functional consequences in
Externí odkaz:
https://doaj.org/article/0285e9b7126643dd88e5200cf082cbaf
Autor:
Dechen Fu, Luke Pfannenstiel, Abeba Demelash, Yee Peng Phoon, Cameron Mayell, Claudia Cabrera, Caini Liu, Junjie Zhao, Josephine Dermawan, Deepa Patil, Jennifer DeVecchio, Matthew Kalady, Andrew J. Souers, Darren C. Phillips, Xiaoxia Li, Brian Gastman
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-11 (2022)
Abstract Colorectal cancer (CRC) is one of the most common and deadliest forms of cancer. Myeloid Cell Leukemia 1 (MCL1), a pro-survival member of the Bcl-2 protein family is associated with chemo-resistance in CRC. The ability of MCL1 to inhibit apo
Externí odkaz:
https://doaj.org/article/01cae53eba704978aeba5dc6a974721f
Autor:
Cheryl M. Cameron, Brian Richardson, Jackelyn B. Golden, Yee Peng Phoon, Banumathi Tamilselvan, Lukas Pfannenstiel, Samjhana Thapaliya, Gustavo Roversi, Xing-Huang Gao, Leah L. Zagore, Mark J. Cameron, Brian R. Gastman
Significant heterogeneity exists within the tumor infiltrating CD8 T cell population, and exhausted T cells harbor a subpopulation that may be replicating and retain signatures of activation, with potential functional consequences in tumor progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a838f91bde676d23a88a8920f8062e
https://doi.org/10.1101/2023.04.02.23288048
https://doi.org/10.1101/2023.04.02.23288048
Autor:
Mogens H. Claesson, Mai-Britt Zocca, Wen Hsin Koo, Simon Ong, Kian Fong Foo, Siew Wan Hee, Sze Huey Tan, Yatanar Soe, Yee Peng Phoon, Kelly Teo, Li Sun, Pia Kvistborg, Whay Kuang Chia, Who-Whong Wang, Han Chong Toh
Supplementary Data from Clinical Benefit of Allogeneic Melanoma Cell Lysate–Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a128b0560ab3af157da1a7ac342aa74
https://doi.org/10.1158/1078-0432.22440432
https://doi.org/10.1158/1078-0432.22440432
Autor:
Mogens H. Claesson, Mai-Britt Zocca, Wen Hsin Koo, Simon Ong, Kian Fong Foo, Siew Wan Hee, Sze Huey Tan, Yatanar Soe, Yee Peng Phoon, Kelly Teo, Li Sun, Pia Kvistborg, Whay Kuang Chia, Who-Whong Wang, Han Chong Toh
Purpose: We evaluated the clinical benefit of an allogeneic melanoma cell lysate (MCL)–pulsed autologous dendritic cell (DC) vaccine in advanced colorectal cancer patients expressing at least one of six MAGE-A antigens overexpressed by the cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0053dc32781966b8265ef9c77bd5e5
https://doi.org/10.1158/1078-0432.c.6517761
https://doi.org/10.1158/1078-0432.c.6517761
Autor:
Eike-Benjamin Braune, Yat Long Tsoi, Yee Peng Phoon, Sebastian Landor, Helena Silva Cascales, Daniel Ramsköld, Qiaolin Deng, Arne Lindqvist, Xiaojun Lian, Cecilia Sahlgren, Shao-Bo Jin, Urban Lendahl
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 643-651 (2016)
Notch signaling is an important regulator of stem cell differentiation. All canonical Notch signaling is transmitted through the DNA-binding protein CSL, and hyperactivated Notch signaling is associated with tumor development; thus it may be anticipa
Externí odkaz:
https://doaj.org/article/27589c4550a849429ff87dd9d4307da5
Autor:
Yee Peng Phoon, Kang Kai, Alexandra Wolfarth, Sara Ferrando-Martinez, Byung Ha Lee, Brian Gastman
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
Clinics in Plastic Surgery. 48:561-576
Despite the ability of immune-based interventions to dramatically increase the survival of patients with melanoma, a significant subset fail to benefit from this treatment, underscoring the need for accurate means to identify the patient population l
Autor:
Yee Peng Phoon, Jared E. Lopes, Lukas W. Pfannenstiel, C. Marcela Diaz-Montero, Ye F. Tian, Marc S. Ernstoff, Pauline Funchain, XiaoXia Li, Heather C. Losey, Raymond J. Winquist, Brian R. Gastman
Publikováno v:
Cancer Research. 83:1818-1818
Introduction: The development and FDA approval of drugs targeting the PD-1/PD-L1 axis has greatly shifted the paradigm of immunotherapy and has improved the clinical outcome for patients diagnosed with advanced melanoma. Despite the recent advancemen