Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yee Mon Thu"'
Autor:
Yee Mon Thu
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
Sumoylation, a process in which SUMO (small ubiquitin like modifier) is conjugated to target proteins, emerges as a post-translational modification that mediates protein−protein interactions, protein complex assembly, and localization of target pro
Externí odkaz:
https://doaj.org/article/e595a963d8a5423483a6638e263a94cb
Autor:
Yee Mon Thu, Susan Kaye Van Riper, LeeAnn Higgins, Tianji Zhang, Jordan Robert Becker, Todd William Markowski, Hai Dang Nguyen, Timothy Jon Griffin, Anja Katrin Bielinsky
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1254-1265 (2016)
Loss of minichromosome maintenance protein 10 (Mcm10) causes replication stress. We uncovered that S. cerevisiae mcm10-1 mutants rely on the E3 SUMO ligase Mms21 and the SUMO-targeted ubiquitin ligase complex Slx5/8 for survival. Using quantitative m
Externí odkaz:
https://doaj.org/article/1108d29655574124884429b3b822a107
Autor:
Hai Dang Nguyen, Jordan Becker, Yee Mon Thu, Michael Costanzo, Elizabeth N Koch, Stephanie Smith, Kyungjae Myung, Chad L Myers, Charles Boone, Anja-Katrin Bielinsky
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66379 (2013)
Deficiency in DNA ligase I, encoded by CDC9 in budding yeast, leads to the accumulation of unligated Okazaki fragments and triggers PCNA ubiquitination at a non-canonical lysine residue. This signal is crucial to activate the S phase checkpoint, whic
Externí odkaz:
https://doaj.org/article/d9ebedc3127d48b08e380a9f2aab0eae
Publikováno v:
Integrative and Comparative Biology
Incorporating active research opportunities into undergraduate curricula is one of the most cited elements demonstrated to improve inclusive excellence and retention in all STEM fields. Allegheny College has a long and nationally-recognized tradition
Autor:
Emily E. Jones, Yee Mon Thu
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36
Autor:
Yee Mon Thu
Publikováno v:
Genetics
Recent work by Kentaro Ohkuni and colleagues exemplifies how a series of molecular mechanisms contribute to a cellular outcome—equal distribution of chromosomes. Failure to maintain structural and numerical integrity of chromosomes is one contribut
Autor:
Julie Cepec, Yee Mon Thu
Publikováno v:
The FASEB Journal. 35
Autor:
Oliver Bonham-Carter, Yee Mon Thu
Publikováno v:
Advances in Intelligent Systems and Computing ISBN: 9783030731021
Interaction between genes is one driving force that can influence a biological outcome. In a genetic disease such as cancer, understanding genetic interactions may help us elucidate mechanisms sustaining cancer growth. A computational approach is one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9e1a34cc3441e37f2b3227ea1707c5
https://doi.org/10.1007/978-3-030-73103-8_5
https://doi.org/10.1007/978-3-030-73103-8_5
Autor:
Timothy K. Starr, Taylor Croissant, David Gallo, Anja Katrin Bielinsky, Wendy Leung, Yee Mon Thu, Grant W. Brown, Hai Dang Nguyen, Jordan R. Becker
Publikováno v:
Nucleic Acids Research
Overexpression of the flap endonuclease FEN1 has been observed in a variety of cancer types and is a marker for poor prognosis. To better understand the cellular consequences of FEN1 overexpression we utilized a model of its Saccharomyces cerevisiae