Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yee Fang Hum"'
Autor:
Yee Fang Hum, Sue Jinks-Robertson
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007302 (2018)
Mitotic recombination can result in loss of heterozygosity and chromosomal rearrangements that shape genome structure and initiate human disease. Engineered double-strand breaks (DSBs) are a potent initiator of recombination, but whether spontaneous
Externí odkaz:
https://doaj.org/article/6c1a1665732d49fca363ca5dd83a4fc5
Autor:
Sue Jinks-Robertson, Yee Fang Hum
Publikováno v:
Nucleic Acids Research
The post-replicative mismatch repair (MMR) system has anti-recombination activity that limits interactions between diverged sequences by recognizing mismatches in strand-exchange intermediates. In contrast to their equivalent roles during replication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035574a7f81305b29f90d5ebd2096a18
https://doi.org/10.1093/nar/gkz126
https://doi.org/10.1093/nar/gkz126
Publikováno v:
Methods Mol Biol
Homologous Recombination ISBN: 9781071606438
Homologous Recombination ISBN: 9781071606438
Mitotic double-strand breaks (DSBs) are repaired by recombination with a homologous donor duplex. This process involves the exchange of single DNA strands between the broken molecule and the repair template, giving rise to regions of heteroduplex DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbfd0ee68ba6c5ecd315b8e44d5a411
https://pubmed.ncbi.nlm.nih.gov/32840801
https://pubmed.ncbi.nlm.nih.gov/32840801
Autor:
Sue Jinks-Robertson, Yee Fang Hum
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007302 (2018)
PLoS Genetics
PLoS Genetics
Mitotic recombination can result in loss of heterozygosity and chromosomal rearrangements that shape genome structure and initiate human disease. Engineered double-strand breaks (DSBs) are a potent initiator of recombination, but whether spontaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6d658931b8aa42bf00229eb7c56b09
http://europepmc.org/articles/PMC5886692?pdf=render
http://europepmc.org/articles/PMC5886692?pdf=render
Autor:
Dazhen Liu, Yee Fang Hum, Jerome Irianto, Roger A. Greenberg, Kuangzheng Zhu, Ruben C. Boot, Leeza M. Santiago Millan, Dan Deviri, Dennis E. Discher, Brandon Niese, Charlotte R. Pfeifer, Yuntao Xia, Victor M. Morales Garcia
Publikováno v:
Biophysical Journal. 116:414a-415a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e0754726a3c1f931478fcbd868d1451
https://doi.org/10.1016/j.bpj.2018.11.2235
https://doi.org/10.1016/j.bpj.2018.11.2235
Summary Heteroduplex DNA (hetDNA) is a key molecular intermediate during the repair of mitotic double-strand breaks by homologous recombination, but its relationship to 5′ end resection and/or 3′ end extension is poorly understood. In the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9375c70bed498cf01101e87f6c0013a3
https://europepmc.org/articles/PMC5584606/
https://europepmc.org/articles/PMC5584606/
Autor:
Yee Fang Hum, Sue Jinks-Robertson
Mitotic recombination between homologous chromosomes leads to the uncovering of recessive alleles through loss of heterozygosity. In the current study, a defined double-strand break was used to initiate reciprocal loss of heterozygosity between diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efe6a8f70989937f591b207680d83fe
https://doi.org/10.1101/132167
https://doi.org/10.1101/132167
Autor:
Yee Fang Hum1, Jinks-Robertson, Sue1 sue.robertson@duke.edu
Publikováno v:
Genetics. Sep2017, Vol. 207 Issue 1, p115-128. 14p.