Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.

Autor: Chapuy B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., McKeown MR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Lin CY; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Monti S; Section of Computational Biomedicine, Boston University School of Medicine, Boston, MA 02118, USA., Roemer MG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Qi J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Rahl PB; Whitehead Institute of Genome Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Sun HH; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA., Yeda KT; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Doench JG; Broad Institute, Cambridge, MA 02142, USA., Reichert E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Kung AL; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA., Young RA; Whitehead Institute of Genome Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Shipp MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. Electronic address: margaret_shipp@dfci.harvard.edu., Bradner JE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. Electronic address: james_bradner@dfci.harvard.edu.

Publikováno v: Cancer cell [Cancer Cell] 2013 Dec 09; Vol. 24 (6), pp. 777-90.