Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yeara Jo"'
Autor:
Lauren K Quezada, Wenhao Jin, Yi Chia Liu, Eleanor S Kim, Zhaoren He, Cynthia S Indralingam, Tiffani Tysl, Lara Labarta-Bajo, Ellen J Wehrens, Yeara Jo, Katelynn R Kazane, Christopher Hattori, Elina I Zuniga, Gene W Yeo, John T Chang
Publikováno v:
PLoS Biology, Vol 21, Iss 1, p e3001983 (2023)
During a microbial infection, responding CD8+ T cells give rise to effector cells that provide acute host defense and memory cells that provide sustained protection. An alternative outcome is exhaustion, a state of T cell dysfunction that occurs in t
Externí odkaz:
https://doaj.org/article/7b4ece8f50d847b580332c8f6b7493f7
Autor:
Djem U Kissiov, Alexander Ethell, Sean Chen, Natalie K Wolf, Chenyu Zhang, Susanna M Dang, Yeara Jo, Katrine N Madsen, Ishan Paranjpe, Angus Y Lee, Bryan Chim, Stefan A Muljo, David H Raulet
Publikováno v:
eLife, Vol 11 (2022)
Mitotically stable random monoallelic gene expression (RME) is documented for a small percentage of autosomal genes. We developed an in vivo genetic model to study the role of enhancers in RME using high-resolution single-cell analysis of natural kil
Externí odkaz:
https://doaj.org/article/9505cd27acaf469ab8f89ecc6921b8c0
Publikováno v:
ACS synthetic biology, vol 11, iss 10
Natural Killer (NK) cells are a major subset of innate immune cells that are essential for host defense against pathogens and cancer. Two main classes of inhibitory NK receptors (NKR), KIR and CD94/NKG2A, play a key role in suppressing NK activity up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0b591b7e02ff3faa57ee4988b83cbe
https://doi.org/10.1021/acssynbio.2c00337
https://doi.org/10.1021/acssynbio.2c00337
Autor:
Djem U. Kissiov, Alexander Ethell, Sean Chen, Natalie K. Wolf, Chenyu Zhang, Susanna M. Dang, Yeara Jo, Katrine N. Madsen, Ishan D. Paranjpe, Angus Y. Lee, Bryan Chim, Stefan A. Muljo, David H. Raulet
Mitotically stable random monoallelic gene expression (RME) is documented for a small percentage of autosomal genes. We developed an in vivo genetic model to study the role of enhancers in RME using high-resolution single-cell analysis of natural kil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe4fd273b954900c9193ef9f401b76e
https://escholarship.org/uc/item/6wj2k8bw
https://escholarship.org/uc/item/6wj2k8bw
Autor:
Djem U Kissiov, Alexander Ethell, Sean Chen, Natalie K Wolf, Chenyu Zhang, Susanna M Dang, Yeara Jo, Katrine N Madsen, Ishan Paranjpe, Angus Y Lee, Bryan Chim, Stefan A Muljo, David H Raulet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13609246c5b1580a08ccec78b586b98a
https://doi.org/10.7554/elife.74204.sa2
https://doi.org/10.7554/elife.74204.sa2
Publikováno v:
Curr Opin Immunol
Plasmacytoid dendritic cells (pDCs) are specialized producers of Type I interferon (IFN-I) that promote anti-viral and anti-tumor immunity. However, chronic infections and cancer inhibit pDC-derived IFN-I. While the mechanisms of this inhibition are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e998ba22c63191fec30f2b76ebee17d8
https://europepmc.org/articles/PMC8526282/
https://europepmc.org/articles/PMC8526282/
Autor:
James A, Harker, Kurt A, Wong, Simone, Dallari, Phuc, Bao, Aleksandr, Dolgoter, Yeara, Jo, Ellen J, Wehrens, Monica, Macal, Elina I, Zuniga
Publikováno v:
Journal of Virology
Chronic viral infections represent a major challenge to the host immune response, and a unique network of immunological elements, including cytokines, are required for their containment. By using a model persistent infection with the natural murine p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::623341657fb10d3302b608dc6fd7eb0d
https://pubmed.ncbi.nlm.nih.gov/29593047
https://pubmed.ncbi.nlm.nih.gov/29593047
Autor:
Simone Dallari, Ellen J. Wehrens, Yeara Jo, Aaron Y. Chang, Shobha Swaminathan, Monica Macal, Jihong Dai, Patricia Fitzgerald-Bocarsly, Elina I. Zuniga
Publikováno v:
Immunity, vol 48, iss 4
Although characterization of Tcell exhaustion has unlocked powerful immunotherapies, the mechanisms sustaining adaptations of short-lived innate cells to chronic inflammatory settings remain unknown. During murine chronic viral infection, we found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea318e458828b4a7fffb074723a7988
https://pubmed.ncbi.nlm.nih.gov/29669251
https://pubmed.ncbi.nlm.nih.gov/29669251
Autor:
Monica Macal, Lee Swanson, Charles Hesser, Elina I. Zuniga, Yeara Jo, Partho Ghosh, Simone Dallari, Maria Eugenia Loureiro
Publikováno v:
Nature Communications
Nature communications, vol 8, iss 1
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature communications, vol 8, iss 1
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Plasmacytoid dendritic cells (pDC) are type I interferon-producing cells with critical functions in a number of human illnesses; however, their molecular regulation is incompletely understood. Here we show the role of Src family kinases (SFK) in mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5747da3dcad86079dd2b36e475692f
https://doi.org/10.1038/ncomms14830
https://doi.org/10.1038/ncomms14830
Publikováno v:
The Journal of Immunology. 202:187.28-187.28
Viruses that cause chronic infections, including Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV), and Hepatitis C virus (HCV), infect more than 500 million people worldwide and represent a major health burden. Chronic viral infections sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b45282ba3a6c3b26e9da388760e42e
https://doi.org/10.4049/jimmunol.202.supp.187.28
https://doi.org/10.4049/jimmunol.202.supp.187.28