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The Bisindole Alkaloids Angustilongines M and A from Alstonia penangiana Induce Mitochondrial Apoptosis and G0/G1 Cell Cycle Arrest in HT-29 Cells through Promotion of Tubulin Polymerization.

Autor: Tan CH; Institute of Biological Sciences, University of Malaya, 50603 Kuala Lumpur, Malaysia., Yeap JS; Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia., Lim SH; Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia., Low YY; Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia., Sim KS; Institute of Biological Sciences, University of Malaya, 50603 Kuala Lumpur, Malaysia., Kam TS; Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Publikováno v: Journal of natural products [J Nat Prod] 2021 May 28; Vol. 84 (5), pp. 1524-1533. Date of Electronic Publication: 2021 Apr 19.

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Akademický článek

Macroline, talpinine, and sarpagine alkaloids from Alstonia penangiana. An NMR-based method for differentiating between A. penangiana and A. macrophylla.

Autor: Yeap JS; Department of Chemistry, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia., Tan CH; Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia., Yong KT; Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia., Lim KH; School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500, Semenyih, Selangor, Malaysia., Lim SH; Department of Chemistry, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia., Low YY; Department of Chemistry, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: yylow@um.edu.my., Kam TS; Department of Chemistry, Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: tskam@um.edu.my.

Publikováno v: Phytochemistry [Phytochemistry] 2020 Aug; Vol. 176, pp. 112391. Date of Electronic Publication: 2020 May 06.

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Akademický článek

Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana .

Autor: Yeap JS; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Saad HM; Institute of Biological Sciences, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Tan CH; Institute of Biological Sciences, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Sim KS; Institute of Biological Sciences, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Lim SH; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Low YY; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Kam TS; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia.

Publikováno v: Journal of natural products [J Nat Prod] 2019 Nov 22; Vol. 82 (11), pp. 3121-3132. Date of Electronic Publication: 2019 Oct 23.

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Akademický článek

Lycopodium Alkaloids: Lycoplatyrine A, an Unusual Lycodine-Piperidine Adduct from Lycopodium platyrhizoma and the Absolute Configurations of Lycoplanine D and Lycogladine H.

Autor: Yeap JS; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Lim KH; School of Pharmacy , University of Nottingham Malaysia Campus , Jalan Broga , 43500 Semenyih , Selangor , Malaysia., Yong KT; Institute of Biological Sciences, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Lim SH; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Kam TS; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia., Low YY; Department of Chemistry, Faculty of Science , University of Malaya , 50603 Kuala Lumpur , Malaysia.

Publikováno v: Journal of natural products [J Nat Prod] 2019 Feb 22; Vol. 82 (2), pp. 324-329. Date of Electronic Publication: 2019 Jan 30.

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Akademický článek

Ajmaline, Oxindole, and Cytotoxic Macroline-Akuammiline Bisindole Alkaloids from Alstonia penangiana.

Autor: Yeap JS, Navanesan S, Sim KS, Yong KT, Gurusamy S; School of Chemical and Life Sciences , Nanyang Polytechnic , 180 Ang Mo Kio Avenue 8 , Singapore 569830 , Singapore., Lim SH, Low YY, Kam TS

Publikováno v: Journal of natural products [J Nat Prod] 2018 May 25; Vol. 81 (5), pp. 1266-1277. Date of Electronic Publication: 2018 May 10.

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