Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia

Autor: Ng, Patricia Miang Lon, Ngoh, Eve Zi Xian, Tan, Hwee Ching, Lee, Chia Yin, Minhat, Rabiatul Adawiyah, Soh, Mun Kuen, Teo, Frannie Jiuyi, Yeap, Yvonne Yee Chin, Seah, Shirley Gek Kheng, Chan, Conrad En Zuo, Hanson, Brendon John, Wang, Cheng-I, Asarnow, Daniel, Wang, Bei, Lee, Wen-Hsin, Hu, Yuanyu, Huang, Ching-Wen, Faust, Bryan, Ng, Patricia, Ngoh, Eve, Bohn, Markus, Bulkley, David, Pizzorno, Andrés, Ary, Beatrice, Tan, Hwee, Lee, Chia, Minhat, Rabiatul, Terrier, Olivier, Soh, Mun, Teo, Frannie, Yeap, Yvonne, Seah, Shirley, Chan, Conrad, Connelly, Emily, Young, Nicholas, Maurer-Stroh, Sebastian, Renia, Laurent, Hanson, Brendon, Rosa-Calatrava, Manuel, Manglik, Aashish, Cheng, Yifan, Craik, Charles, Wang, Null

Publikováno v: Cells
Cells, 2021, ⟨10.1016/j.cell.2021.04.033⟩
Cell
Cell, vol 184, iss 12
Cells, MDPI, 2021, ⟨10.1016/j.cell.2021.04.033⟩
Cell, Elsevier, 2021, 184 (12), pp.3192-3204.e16. ⟨10.1016/j.cell.2021.04.033⟩

Infection by SARS-CoV-2 is initiated by binding of viral Spike protein to host receptor angiotensin-converting enzyme 2 (ACE2), followed by fusion of viral and host membranes. While antibodies that block this interaction are in emergency use as early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5a715cabddd4d6e479ee53a1805366
https://pubmed.ncbi.nlm.nih.gov/33974910