Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yean-Ju Hong"'
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101401- (2022)
Summary: Mitochondrial dynamics play critical roles in both tissue homeostasis and somatic cell reprogramming. Here, we provide integrated guidance for assessing mitochondrial function and dynamics while reprogramming human fibroblasts via an integra
Externí odkaz:
https://doaj.org/article/316fdc906e394459bf39c17657e605b9
Autor:
Jae-Hoon Song, Joonhyuk Choi, Yean-Ju Hong, Hyeonwoo La, Tae-Kyung Hong, Kwonho Hong, Jeong-Tae Do
Publikováno v:
Cells, Vol 11, Iss 20, p 3266 (2022)
As a novel cell type from eight-cell-stage embryos, extended pluripotent stem cells (EPSCs) are known for diverse differentiation potency in both extraembryonic and embryonic lineages, suggesting new possibilities as a developmental research model. A
Externí odkaz:
https://doaj.org/article/cf82151e663e497c9f20502b6ff2a505
Autor:
Won Ji Lee, Jeong Eon Lee, Yean Ju Hong, Sang Hoon Yoon, Hyuk Song, Chankyu Park, Kwonho Hong, Youngsok Choi, Jeong Tae Do
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102100- (2020)
Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs), can differentiate into all cell types in the body; therefore, they are used in the study of development and regenerative medicine. Neural lineage differentiation from PSCs is the i
Externí odkaz:
https://doaj.org/article/6da48705567c4ac9bbbb567ba79c26d1
Autor:
Joonhyuk Choi, Bong Jong Seo, Hyeonwoo La, Sang Hoon Yoon, Yean Ju Hong, Ji-Heon Lee, Hyung-Min Chung, Kwonho Hong, Jeong Tae Do
Publikováno v:
Redox Biology, Vol 30, Iss , Pp - (2020)
Pre-implantation mouse blastocyst-derived stem cells, namely embryonic stem cells (ESCs), trophoblast stem cells (TSCs), and extraembryonic endoderm (XEN) cells, have their own characteristics and lineage specificity. So far, several studies have att
Externí odkaz:
https://doaj.org/article/6516ec58d7a843739d025c53c6ae6f3c
Autor:
Jeong Eon Lee, Bong Jong Seo, Min Ji Han, Yean Ju Hong, Kwonho Hong, Hyuk Song, Jeong Woong Lee, Jeong Tae Do
Publikováno v:
Stem Cells International, Vol 2020 (2020)
During embryonic development, cells undergo changes in gene expression, signaling pathway activation/inactivation, metabolism, and intracellular organelle structures, which are mediated by mitochondria. Mitochondria continuously switch their morpholo
Externí odkaz:
https://doaj.org/article/08b215ff185940229f1bdf094d83ca55
Autor:
Yean Ju Hong, Jeong Tae Do
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Recent advances in induced pluripotent stem cell (iPSC) research have turned limitations of prior and current research into possibilities. iPSCs can differentiate into the desired cell types, are easier to obtain than embryonic stem cells (ESCs), and
Externí odkaz:
https://doaj.org/article/b6a24945b52a4791bcc928625ce33ea3
Autor:
Hyun Woo Choi, Jin Young Joo, Yean Ju Hong, Jong Soo Kim, Hyuk Song, Jeong Woong Lee, Guangming Wu, Hans R. Schöler, Jeong Tae Do
Publikováno v:
Stem Cell Reports, Vol 7, Iss 5, Pp 911-926 (2016)
Naive and primed pluripotent stem cells (PSCs) and germ cells express the Oct4 gene. The Oct4 gene contains two cis-regulatory elements, the distal enhancer (DE) and proximal enhancer (PE), which differentially control Oct4 expression in a cell-type-
Externí odkaz:
https://doaj.org/article/7737eb4f31c54634926f9776ef79b1c0
Publikováno v:
International Journal of Stem Cells. 15:95-103
In recent years, brain organoid technologies have been the most innovative advance in neural differentiation research. In line with this, we optimized a method to establish cerebral organoids from feeder-free cultured human pluripotent stem cells. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99520612c7cb9d98599509cc8eb8c3c
https://doi.org/10.15283/ijsc21195
https://doi.org/10.15283/ijsc21195
Autor:
Ji-Hye Seo, Si Won Jang, Young-Joo Jeon, So Young Eun, Yean Ju Hong, Jeong Tae Do, Jung-il Chae, Hyun Woo Choi
Publikováno v:
Journal of microbiology and biotechnology. 32(10)
Induced pluripotent stem cells (iPSCs) can be generated from somatic cells using Oct4, Sox2, Klf4, and c-Myc (OSKM). Small molecules can enhance reprogramming. Licochalcone D (LCD), a flavonoid compound present mainly in the roots of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9915e9c0ec234994b3ebcea664e3a06c
https://pubmed.ncbi.nlm.nih.gov/36575652
https://pubmed.ncbi.nlm.nih.gov/36575652
Autor:
Hyun Woo Choi, Yean Ju Hong, Jong Soo Kim, Hyuk Song, Ssang Gu Cho, Hojae Bae, Changsung Kim, Sung June Byun, Jeong Tae Do
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170735 (2017)
Like embryonic stem cells, induced pluripotent stem cells (iPSCs) can differentiate into all three germ layers in an in vitro system. Here, we developed a new technology for obtaining neural stem cells (NSCs) from iPSCs through chimera formation, in
Externí odkaz:
https://doaj.org/article/e09e85449c0f4b14998c53c41d090533